Regulating insulin signaling and beta-cell function through IRS proteins. - Wikidata - awgldk - TriplyDB

Regulating insulin signaling and beta-cell function through IRS proteins.

Regulating insulin signaling and beta-cell function through IRS proteins.

http://www.wikidata.org/entity/Q36602630

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Identification of a WD40 repeat-containing isoform of PHIP as a novel regulator of beta-cell growth and survival Brain Insulin Resistance at the Crossroads of Metabolic and Cognitive Disorders in Humans Insulin receptor signaling in normal and insulin-resistant states The full-length isoform of the mouse pleckstrin homology domain-interacting protein (PHIP) is required for postnatal growth Chronic 17beta-estradiol treatment improves skeletal muscle insulin signaling pathway components in insulin resistance associated with aging Rescue of obesity-induced infertility in female mice due to a pituitary-specific knockout of the insulin receptor.Insulin receptor substrate 2 (IRS2)-deficient mice show sensorineural hearing loss that is delayed by concomitant protein tyrosine phosphatase 1B (PTP1B) loss of function Insulin resistance in non-obese subjects is associated with activation of the JNK pathway and impaired insulin signaling in skeletal muscle.Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance Hyperleptinemia is required for the development of leptin resistance.Inhibition of PTP1B restores IRS1-mediated hepatic insulin signaling in IRS2-deficient mice.Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain.Glycogen synthase kinase-3β is associated with the prognosis of hepatocellular carcinoma and may mediate the influence of type 2 diabetes mellitus on hepatocellular carcinoma.BH3-only molecule Bim mediates β-cell death in IRS2 deficiency.Conditional ablation of Gsk-3β in islet beta cells results in expanded mass and resistance to fat feeding-induced diabetes in mice Progression from high insulin resistance to type 2 diabetes does not entail additional visceral adipose tissue inflammation.Influence of energy balance on the somatotrophic axis and matrix metalloproteinase expression in the endometrium of the postpartum dairy cow.Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor.Novel insights into the function of β-cell M3 muscarinic acetylcholine receptors: therapeutic implications.Improved insulin sensitivity by calorie restriction is associated with reduction of ERK and p70S6K activities in the liver of obese Zucker rats Cyclin-dependent kinase 5 promotes pancreatic β-cell survival via Fak-Akt signaling pathways.Insulin receptor substrate 2 expression and involvement in neuronal insulin resistance in diabetic neuropathy Resequencing of IRS2 reveals rare variants for obesity but not fasting glucose homeostasis in Hispanic children Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via Ca2+-dependent calcineurin/NFAT signaling in primary pancreatic islet β-cells.Reproductive tissues maintain insulin sensitivity in diet-induced obesity.ROS constitute a convergence nexus in the development of IGF1 resistance and impaired wound healing in a rat model of type 2 diabetes.Metabolic stress signaling mediated by mixed-lineage kinases.Effects of E2HSA, a Long-Acting Glucagon Like Peptide-1 Receptor Agonist, on Glycemic Control and Beta Cell Function in Spontaneous Diabetic db/db Mice Activation of G proteins by GIV-GEF is a pivot point for insulin resistance and sensitivity.Regulation of Glucokinase by Intracellular Calcium Levels in Pancreatic β Cells IGF2: epigenetic regulation and role in development and disease.Insulin stimulates primary beta-cell proliferation via Raf-1 kinase.Critical metabolic roles of β-cell M3 muscarinic acetylcholine receptors Brain-Wide Insulin Resistance, Tau Phosphorylation Changes, and Hippocampal Neprilysin and Amyloid-β Alterations in a Monkey Model of Type 1 Diabetes.Trimeprazine increases IRS2 in human islets and promotes pancreatic β cell growth and function in mice Insulin-like growth factor I receptor signaling is required for exercise-induced cardiac hypertrophy.Direct autocrine action of insulin on β-cells: does it make physiological sense?Insulin receptor substrate-2 regulates aerobic glycolysis in mouse mammary tumor cells via glucose transporter 1.Role of microRNAs in diabetes.Stage debut for the elusive Drosophila insulin-like growth factor binding protein.

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Regulating insulin signaling and beta-cell function through IRS proteins.

http://www.wikidata.org/entity/Q36602630

description

2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年论文

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2006年论文

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2006年论文

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name

Regulating insulin signaling and beta-cell function through IRS proteins.

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Regulating insulin signaling and beta-cell function through IRS proteins.

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Regulating insulin signaling and beta-cell function through IRS proteins.

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Regulating insulin signaling and beta-cell function through IRS proteins.

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Regulating insulin signaling and beta-cell function through IRS proteins.

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Canadian Journal of Physiology and Pharmacology

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Regulating insulin signaling and beta-cell function through IRS proteins.

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Morris F White

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P2860

CAP defines a second signalling pathway required for insulin-stimulated glucose transport

Insulin stimulates PKCzeta -mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins

Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10

Modulation of human insulin receptor substrate-1 tyrosine phosphorylation by protein kinase Cdelta

Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence

SH2-Balpha is an insulin-receptor adapter protein and substrate that interacts with the activation loop of the insulin-receptor kinase

Disruption of IRS-2 causes type 2 diabetes in mice

Increased insulin sensitivity in mice lacking p85beta subunit of phosphoinositide 3-kinase

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