Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway
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The phosphorylation of CapZ-interacting protein (CapZIP) by stress-activated protein kinases triggers its dissociation from CapZActivation loop phosphorylation of ERK3/ERK4 by group I p21-activated kinases (PAKs) defines a novel PAK-ERK3/4-MAPK-activated protein kinase 5 signaling pathwayActivation and function of the MAPKs and their substrates, the MAPK-activated protein kinasesThe extracellular signal-regulated kinase 3 (mitogen-activated protein kinase 6 [MAPK6])-MAPK-activated protein kinase 5 signaling complex regulates septin function and dendrite morphologyComparative Analysis of Two Gene-Targeting Approaches Challenges the Tumor-Suppressive Role of the Protein Kinase MK5/PRAKThe diterpenoid alkaloid noroxoaconitine is a Mapkap kinase 5 (MK5/PRAK) inhibitorCharacterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5Physiological roles of mitogen-activated-protein-kinase-activated p38-regulated/activated protein kinaseERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5.A Pilot Study for Discovering Candidate Genes of Chromosome 18q21 in Methamphetamine Abusers: Case-control Association Study.Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cellsERK3 is required for metaphase-anaphase transition in mouse oocyte meiosisThe catalytic activity of the mitogen-activated protein kinase extracellular signal-regulated kinase 3 is required to sustain CD4+ CD8+ thymocyte survival.Absence of a human DnaJ protein hTid-1S correlates with aberrant actin cytoskeleton organization in lesional psoriatic skin.Up-regulated microRNA499a by hepatitis B virus induced hepatocellular carcinogenesis via targeting MAPK6Targeted inactivation of Mapk4 in mice reveals specific nonredundant functions of Erk3/Erk4 subfamily mitogen-activated protein kinases.PRAK interacts with DJ-1 and prevents oxidative stress-induced cell death.Identification of the atypical MAPK Erk3 as a novel substrate for p21-activated kinase (Pak) activityCross-Phosphorylation and Interaction between Src/FAK and MAPKAP5/PRAK in Early Focal Adhesions Controls Cell MotilityIGF2BP1 promotes cell migration by regulating MK5 and PTEN signalingERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion.MAP kinase pathways: the first twenty years.Identification and proteomic analysis of distinct UBE3A/E6AP protein complexes.p38gamma mitogen-activated protein kinase integrates signaling crosstalk between Ras and estrogen receptor to increase breast cancer invasionThe novel RAGE interactor PRAK is associated with autophagy signaling in Alzheimer's disease pathogenesisCharacterization of hsp27 kinases activated by elevated aortic pressure in heart.ERK3 regulates TDP2-mediated DNA damage response and chemoresistance in lung cancer cells.A novel role for atypical MAPK kinase ERK3 in regulating breast cancer cell morphology and migrationDocking of PRAK/MK5 to the atypical MAPKs ERK3 and ERK4 defines a novel MAPK interaction motif.Loss of Erk3 function in mice leads to intrauterine growth restriction, pulmonary immaturity, and neonatal lethality.Regulation of atypical MAP kinases ERK3 and ERK4 by the phosphatase DUSP2.Comparative molecular dynamics simulations of mitogen-activated protein kinase-activated protein kinase 5.Cross-talk between protein kinase A and the MAPK-activated protein kinases RSK1 and MK5.Tumour promoting and suppressing roles of the atypical MAP kinase signalling pathway ERK3/4-MK5MAP Kinase Cascades in Antigen Receptor Signaling and Physiology.Deubiquitinating Enzyme USP20 Regulates Extracellular Signal-Regulated Kinase 3 Stability and Biological Activity.MK5 activates Rag transcription via Foxo1 in developing B cells.Characterization of the expression and regulation of MK5 in the murine ventricular myocardium.The transcriptional regulation and cell-specific expression of the MAPK-activated protein kinase MK5.A novel function of p38-regulated/activated kinase in endothelial cell migration and tumor angiogenesis.
P2860
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P2860
Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway
description
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Dezember 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/12/08)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/12/08)
@nl
наукова стаття, опублікована в грудні 2004
@uk
مقالة علمية (نشرت في 8-12-2004)
@ar
name
Activation of MK5/PRAK by the ...... el signal transduction pathway
@ast
Activation of MK5/PRAK by the ...... el signal transduction pathway
@en
Activation of MK5/PRAK by the ...... el signal transduction pathway
@nl
type
label
Activation of MK5/PRAK by the ...... el signal transduction pathway
@ast
Activation of MK5/PRAK by the ...... el signal transduction pathway
@en
Activation of MK5/PRAK by the ...... el signal transduction pathway
@nl
prefLabel
Activation of MK5/PRAK by the ...... el signal transduction pathway
@ast
Activation of MK5/PRAK by the ...... el signal transduction pathway
@en
Activation of MK5/PRAK by the ...... el signal transduction pathway
@nl
P2093
P2860
P356
P1433
P1476
Activation of MK5/PRAK by the ...... el signal transduction pathway
@en
P2093
Benjamin Turgeon
Bjarne Johansen
Chris G Armstrong
Espen Michaelsen
Nick A Morrice
Sylvain Meloche
Theresa Mikalsen
P2860
P304
P356
10.1038/SJ.EMBOJ.7600489
P407
P577
2004-12-02T00:00:00Z