Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth
about
Cbl-mediated degradation of Lyn and Fyn induced by constitutive fibroblast growth factor receptor-2 activation supports osteoblast differentiationIntracellular retention, degradation, and signaling of glycosylation-deficient FGFR2 and craniosynostosis syndrome-associated FGFR2C278Fβ-catenin regulates mesenchymal progenitor cell differentiation during hepatogenesisGrowth of the normal skull vault and its alteration in craniosynostosis: insights from human genetics and experimental studiesFibroblast growth factor signaling in skeletal development and diseaseA pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturationAnisotropic stress orients remodelling of mammalian limb bud ectoderm.Genetic insights into the mechanisms of Fgf signalingUtilizing past and present mouse systems to engineer more relevant pancreatic cancer modelsFGF signaling expands embryonic cortical surface area by regulating Notch-dependent neurogenesisTestis development requires the repression of Wnt4 by Fgf signalingGenetic tools for identifying and manipulating fibroblasts in the mouseLung epithelial branching program antagonizes alveolar differentiationFgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuitsAn FGF-WNT gene regulatory network controls lung mesenchyme developmentFibroblast growth factor receptor signaling is essential for lens fiber cell differentiationFormation and differentiation of multiple mesenchymal lineages during lung development is regulated by beta-catenin signalingWnt/beta-catenin signaling is sufficient and necessary for synovial joint formationGain-of-function mutation in FGFR3 in mice leads to decreased bone mass by affecting both osteoblastogenesis and osteoclastogenesisOsteocyte-specific deletion of Fgfr1 suppresses FGF23Expression of osterix Is Regulated by FGF and Wnt/β-Catenin Signalling during Osteoblast DifferentiationMesodermal deletion of transforming growth factor-beta receptor II disrupts lung epithelial morphogenesis: cross-talk between TGF-beta and Sonic hedgehog pathwaysEarly onset of craniosynostosis in an Apert mouse model reveals critical features of this pathologyFGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glandsConcerted action of Msx1 and Msx2 in regulating cranial neural crest cell differentiation during frontal bone developmentEarly thyroid development requires a Tbx1-Fgf8 pathwayTissue-specific requirements of beta-catenin in external genitalia developmentFrs2α enhances fibroblast growth factor-mediated survival and differentiation in lens developmentOsteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodelingFGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopodSpatial-temporal targeting of lung-specific mesenchyme by a Tbx4 enhancerDelineating a conserved genetic cassette promoting outgrowth of body appendagesGpr177 regulates pulmonary vasculature developmentCochlear progenitor number is controlled through mesenchymal FGF receptor signalingInactivation of fibroblast growth factor receptor signaling in myelinating glial cells results in significant loss of adult spiral ganglion neurons accompanied by age-related hearing impairment.A perfusion-independent role of blood vessels in determining branching stereotypy of lung airwaysFGF10/FGFR2b signaling is essential for cardiac fibroblast development and growth of the myocardium.FGF ligands of the postnatal mammary stroma regulate distinct aspects of epithelial morphogenesis.Mosaic analysis of cell rearrangements during ureteric bud branching in dissociated/reaggregated kidney cultures and in vivo.The transition from radial glial to intermediate progenitor cell is inhibited by FGF signaling during corticogenesis.
P2860
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P2860
Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth
description
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im Juli 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/07/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/07/01)
@nl
наукова стаття, опублікована в липні 2003
@uk
مقالة علمية (نشرت في يوليو 2003)
@ar
name
Conditional inactivation of FG ...... blast function and bone growth
@ast
Conditional inactivation of FG ...... blast function and bone growth
@en
Conditional inactivation of FG ...... blast function and bone growth
@nl
type
label
Conditional inactivation of FG ...... blast function and bone growth
@ast
Conditional inactivation of FG ...... blast function and bone growth
@en
Conditional inactivation of FG ...... blast function and bone growth
@nl
prefLabel
Conditional inactivation of FG ...... blast function and bone growth
@ast
Conditional inactivation of FG ...... blast function and bone growth
@en
Conditional inactivation of FG ...... blast function and bone growth
@nl
P2093
P3181
P356
P1433
P1476
Conditional inactivation of FG ...... blast function and bone growth
@en
P2093
David M. Ornitz
Drazen Sosic
Dwight A. Towler
Eric N. Olson
Jiansu Shao
Jingsong Xu
Zhonghao Liu
P304
P3181
P356
10.1242/DEV.00491
P407
P577
2003-07-01T00:00:00Z