Arrest in primitive erythroid cell development caused by promoter-specific disruption of the GATA-1 gene
about
Potentiation of GATA-2 activity through interactions with the promyelocytic leukemia protein (PML) and the t(15;17)-generated PML-retinoic acid receptor alpha oncoproteinEssential and instructive roles of GATA factors in eosinophil developmentKnockdown of ZNF268, which is transcriptionally downregulated by GATA-1, promotes proliferation of K562 cellsExpression and potential role of GATA factors in trophoblast developmentTranscription factor GATA-1 and Down syndrome leukemogenesisRescue of the embryonic lethal hematopoietic defect reveals a critical role for GATA-2 in urogenital developmentZic2 regulates the kinetics of neurulationDefective development of secretory neurones in the hypothalamus of Arnt2-knockout miceGenome-wide ENU mutagenesis in combination with high density SNP analysis and exome sequencing provides rapid identification of novel mouse models of developmental diseaseEndothelial Cell-Selective Adhesion Molecule Expression in Hematopoietic Stem/Progenitor Cells Is Essential for Erythropoiesis Recovery after Bone Marrow InjuryLoss of the Gata1 gene IE exon leads to variant transcript expression and the production of a GATA1 protein lacking the N-terminal domainTranscription factor GATA1 is dispensable for mast cell differentiation in adult micePathological interactions between hematopoietic stem cells and their niche revealed by mouse models of primary myelofibrosis.GATA1 function, a paradigm for transcription factors in hematopoiesisMafA is a key regulator of glucose-stimulated insulin secretion.Dynamic regulation of Gata1 expression during the maturation of conventional dendritic cells.Localization of distant urogenital system-, central nervous system-, and endocardium-specific transcriptional regulatory elements in the GATA-3 locus.Genetic analysis of hierarchical regulation for Gata1 and NF-E2 p45 gene expression in megakaryopoiesisSENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis.One enhancer mediates mafK transcriptional activation in both hematopoietic and cardiac muscle cells.GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene.A GATA box in the GATA-1 gene hematopoietic enhancer is a critical element in the network of GATA factors and sites that regulate this gene.Lineage-specific combinatorial action of enhancers regulates mouse erythroid Gata1 expressionIn vivo requirements for GATA-1 functional domains during primitive and definitive erythropoiesis.GATA1-mediated megakaryocyte differentiation and growth control can be uncoupled and mapped to different domains in GATA1Combinatorial Gata2 and Sca1 expression defines hematopoietic stem cells in the bone marrow niche.The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in miceDifferential sensitivities of transcription factor target genes underlie cell type-specific gene expression profiles.GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodelingSpecific contribution of the erythropoietin gene 3' enhancer to hepatic erythropoiesis after late embryonic stages.The Human GATA1 Gene Retains a 5' Insulator That Maintains Chromosomal Architecture and GATA1 Expression Levels in Splenic ErythroblastsThe hypomorphic Gata1low mutation alters the proliferation/differentiation potential of the common megakaryocytic-erythroid progenitor.Effect of transcription-factor concentrations on leukemic stem cells.Early block to erythromegakaryocytic development conferred by loss of transcription factor GATA-1.Developmental regulation of yolk sac hematopoiesis by Kruppel-like factor 6N- and C-terminal transactivation domains of GATA1 protein coordinate hematopoietic programRole of GATA-1 in normal and neoplastic hemopoiesis.GATA-1 utilizes Ikaros and polycomb repressive complex 2 to suppress Hes1 and to promote erythropoiesisLSD1/KDM1A promotes hematopoietic commitment of hemangioblasts through downregulation of Etv2.Molecular mechanism of allergy-related gene regulation and hematopoietic cell development by transcription factors.
P2860
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P2860
Arrest in primitive erythroid cell development caused by promoter-specific disruption of the GATA-1 gene
description
1997 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1997
@ast
im Mai 1997 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1997/05/09)
@sk
vědecký článek publikovaný v roce 1997
@cs
wetenschappelijk artikel (gepubliceerd op 1997/05/09)
@nl
наукова стаття, опублікована в травні 1997
@uk
name
Arrest in primitive erythroid ...... disruption of the GATA-1 gene
@ast
Arrest in primitive erythroid ...... disruption of the GATA-1 gene
@en
Arrest in primitive erythroid ...... disruption of the GATA-1 gene
@nl
type
label
Arrest in primitive erythroid ...... disruption of the GATA-1 gene
@ast
Arrest in primitive erythroid ...... disruption of the GATA-1 gene
@en
Arrest in primitive erythroid ...... disruption of the GATA-1 gene
@nl
prefLabel
Arrest in primitive erythroid ...... disruption of the GATA-1 gene
@ast
Arrest in primitive erythroid ...... disruption of the GATA-1 gene
@en
Arrest in primitive erythroid ...... disruption of the GATA-1 gene
@nl
P2093
P2860
P3181
P356
P1476
Arrest in primitive erythroid ...... disruption of the GATA-1 gene
@en
P2093
H. Motohashi
K. Onodera
M. Yamamoto
N. Hayashi
S. Takahashi
Y. Nabesima
P2860
P304
12611–12615
P3181
P356
10.1074/JBC.272.19.12611
P407
P577
1997-05-09T00:00:00Z