Polg2 is essential for mammalian embryogenesis and is required for mtDNA maintenance
about
High-resolution profiles of gene expression and DNA methylation highlight mitochondrial modifications during early embryonic development.DNA polymerases in the mitochondria: A critical review of the evidence.NAG-1/GDF-15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism.Defects of mitochondrial DNA replication.Impaired cardiac energy metabolism in embryos lacking adrenergic stimulation.Mitochondrial Diseases Part II: Mouse models of OXPHOS deficiencies caused by defects in regulatory factors and other components required for mitochondrial function.Cumulative mtDNA damage and mutations contribute to the progressive loss of RGCs in a rat model of glaucomaPOLG2 disease variants: analyses reveal a dominant negative heterodimer, altered mitochondrial localization and impaired respiratory capacity.Complementation between polymerase- and exonuclease-deficient mitochondrial DNA polymerase mutants in genomically engineered flies.POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA.Human mitochondrial DNA replication machinery and disease.Inherited mitochondrial genomic instability and chemical exposures.Role of the mitochondrial DNA replication machinery in mitochondrial DNA mutagenesis, aging and age-related diseases.Dynamic comparisons of high-resolution expression profiles highlighting mitochondria-related genes between in vivo and in vitro fertilized early mouse embryos.POLG2 deficiency causes adult-onset syndromic sensory neuropathy, ataxia and parkinsonism.Whole exome sequencing identifies a homozygous POLG2 missense variant in an infant with fulminant hepatic failure and mitochondrial DNA depletion.Off-Target Effects of Drugs that Disrupt Human Mitochondrial DNA Maintenance.DNA polymerase β: A missing link of the base excision repair machinery in mammalian mitochondria.Mitochondrial dysfunction and ovarian aging.Characterization of the human homozygous R182W POLG2 mutation in mitochondrial DNA depletion syndromeMitochondrial DNA replication in mammalian cells: overview of the pathway
P2860
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P2860
Polg2 is essential for mammalian embryogenesis and is required for mtDNA maintenance
description
2013 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2013
@ast
im März 2013 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2013/03/01)
@sk
vědecký článek publikovaný v roce 2013
@cs
wetenschappelijk artikel (gepubliceerd op 2013/03/01)
@nl
наукова стаття, опублікована в березні 2013
@uk
مقالة علمية (نشرت في مارس 2013)
@ar
name
Polg2 is essential for mammalian embryogenesis and is required for mtDNA maintenance
@ast
Polg2 is essential for mammalian embryogenesis and is required for mtDNA maintenance
@en
Polg2 is essential for mammalian embryogenesis and is required for mtDNA maintenance
@nl
type
label
Polg2 is essential for mammalian embryogenesis and is required for mtDNA maintenance
@ast
Polg2 is essential for mammalian embryogenesis and is required for mtDNA maintenance
@en
Polg2 is essential for mammalian embryogenesis and is required for mtDNA maintenance
@nl
prefLabel
Polg2 is essential for mammalian embryogenesis and is required for mtDNA maintenance
@ast
Polg2 is essential for mammalian embryogenesis and is required for mtDNA maintenance
@en
Polg2 is essential for mammalian embryogenesis and is required for mtDNA maintenance
@nl
P2093
P2860
P3181
P356
P1476
Polg2 is essential for mammalian embryogenesis and is required for mtDNA maintenance
@en
P2093
Arun R Pandiri
Greg S Travlos
Julie F Foley
Margaret M Humble
Matthew J Young
P2860
P304
P3181
P356
10.1093/HMG/DDS506
P577
2012-11-29T00:00:00Z