NAG-1/GDF-15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism.
about
GDF-15 as a Target and Biomarker for Diabetes and Cardiovascular Diseases: A Translational ProspectiveNAG-1/GDF15 accumulates in the nucleus and modulates transcriptional regulation of the Smad pathwayExpression of Human NSAID Activated Gene 1 in Mice Leads to Altered Mammary Gland Differentiation and Impaired LactationhNAG-1 increases lifespan by regulating energy metabolism and insulin/IGF-1/mTOR signalingIL-15Rα is a determinant of muscle fuel utilization, and its loss protects against obesity.Cardiac-Secreted Factors as Peripheral Metabolic Regulators and Potential Disease Biomarkers.Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.Hitting the Bull's-Eye in Metastatic Cancers-NSAIDs Elevate ROS in Mitochondria, Inducing Malignant Cell Death.The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL.Moonlighting proteins in cancer.Anorexia-cachexia and obesity treatment may be two sides of the same coin: role of the TGF-b superfamily cytokine MIC-1/GDF15.Secreted growth differentiation factor 15 as a potential biomarker for mitochondrial dysfunctions in aging and age-related disorders.Pharmacologic activation of estrogen receptor β increases mitochondrial function, energy expenditure, and brown adipose tissue.Muscle mitochondrial stress adaptation operates independently of endogenous FGF21 action.Over-production of growth differentiation factor 15 (GDF15) promotes human rhinovirus infection and virus-induced inflammation in the lung.Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys.Treatment with the TGF-b superfamily cytokine MIC-1/GDF15 reduces the adiposity and corrects the metabolic dysfunction of mice with diet-induced obesity.Exercise increases circulating GDF15 in humans.Fasting exacerbates hepatic growth differentiation factor 15 to promote fatty acid β-oxidation and ketogenesis via activating XBP1 signaling in liver.Growth differentiation factor 15 contributes to marrow adipocyte remodeling in response to the growth of leukemic cells.Reduced oxidative capacity in macrophages results in systemic insulin resistance.Moonlighting Activity of Secreted Inflammation-Regulatory Proteins.Dual Effects of Metformin on Adipogenic Differentiation of 3T3-L1 Preadipocyte in AMPK-Dependent and Independent Manners.GDF15 deficiency promotes high fat diet-induced obesity in mice
P2860
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P2860
NAG-1/GDF-15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism.
description
2014 nî lūn-bûn
@nan
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
NAG-1/GDF-15 prevents obesity ...... ysis and oxidative metabolism.
@ast
NAG-1/GDF-15 prevents obesity ...... ysis and oxidative metabolism.
@en
NAG-1/GDF-15 prevents obesity ...... ysis and oxidative metabolism.
@nl
type
label
NAG-1/GDF-15 prevents obesity ...... ysis and oxidative metabolism.
@ast
NAG-1/GDF-15 prevents obesity ...... ysis and oxidative metabolism.
@en
NAG-1/GDF-15 prevents obesity ...... ysis and oxidative metabolism.
@nl
prefLabel
NAG-1/GDF-15 prevents obesity ...... ysis and oxidative metabolism.
@ast
NAG-1/GDF-15 prevents obesity ...... ysis and oxidative metabolism.
@en
NAG-1/GDF-15 prevents obesity ...... ysis and oxidative metabolism.
@nl
P2093
P2860
P356
P1476
NAG-1/GDF-15 prevents obesity ...... ysis and oxidative metabolism.
@en
P2093
K Chrysovergis
P2860
P2888
P304
P356
10.1038/IJO.2014.27
P407
P577
2014-02-17T00:00:00Z
P5875
P6179
1053190827