Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice
about
The human cytomegalovirus UL11 protein interacts with the receptor tyrosine phosphatase CD45, resulting in functional paralysis of T cellsThe LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesionsLck-dependent tyrosyl phosphorylation of the phosphotyrosine phosphatase SH-PTP1 in murine T cellsIdentification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST.Aggregation of IgE receptors in rat basophilic leukemia 2H3 cells induces tyrosine phosphorylation of the cytosolic protein-tyrosine phosphatase HePTPCD45-associated protein is not essential for the regulation of antigen receptor-mediated signal transductionInterleukin-6, CD45 and the src-kinases in myeloma cell proliferation77 C/G mutation in the tyrosine phosphatase CD45 gene and autoimmune hepatitis: evidence for a genetic linkIdentification of the sites of interaction between lymphocyte phosphatase-associated phosphoprotein (LPAP) and CD45Protein tyrosine phosphatases and the immune responseImpaired development of V gamma 3 dendritic epidermal T cells in p56lck protein tyrosine kinase-deficient and CD45 protein tyrosine phosphatase-deficient miceSignaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphataseExpression of the p56(Lck) Y505F mutation in CD45-deficient mice rescues thymocyte developmentHematopoietic protein tyrosine phosphatase suppresses extracellular stimulus-regulated kinase activationCD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturationThe motheaten mutation rescues B cell signaling and development in CD45-deficient miceSmooth-muscle contraction without smooth-muscle myosinPhosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptorAltered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient miceDevelopment of T-leukaemias in CD45 tyrosine phosphatase-deficient mutant lck miceThe SHB adapter protein is required for normal maturation of mesoderm during in vitro differentiation of embryonic stem cellsSevere combined immunodeficiencies (SCID)Anti-CD45RO suppresses human immunodeficiency virus type 1 replication in microglia: role of Hck tyrosine kinase and implications for AIDS dementia.The tyrosine phosphatase SHP-1 influences thymocyte selection by setting TCR signaling thresholds.SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levelsPSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcR gamma to induce slow leukocyte rolling.A supramolecular basis for CD45 tyrosine phosphatase regulation in sustained T cell activationPhosphorylation of CD45 by casein kinase 2. Modulation of activity and mutational analysis.PU.1 is a lineage-specific regulator of tyrosine phosphatase CD45.Recirculating and marginal zone B cell populations can be established and maintained independently of primary and secondary follicles.Leishmania major intracellular survival is not altered in SHP-1 deficient mev or CD45-/- mice.T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl-transferase gene by site-directed recombinationNovel tools to dissect the dynamic regulation of TCR signaling by the kinase Csk and the phosphatase CD45Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient miceCD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic developmentB cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals.Proliferation of immature myeloma cells by interleukin-6 is associated with CD45 expression in human multiple myeloma.Isolation and characterization of intestinal epithelial cells from normal and SIV-infected rhesus macaquesA major susceptibility locus for systemic lupus erythemathosus maps to chromosome 1q31Deficiency in expression of the signaling protein Sin/Efs leads to T-lymphocyte activation and mucosal inflammation.
P2860
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P2860
Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice
description
1993 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1993
@ast
im Juli 1993 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1993/07/16)
@sk
vědecký článek publikovaný v roce 1993
@cs
wetenschappelijk artikel (gepubliceerd op 1993/07/16)
@nl
наукова стаття, опублікована в липні 1993
@uk
مقالة علمية (نشرت في 16-7-1993)
@ar
name
Normal B lymphocyte developmen ...... ine phosphatase-deficient mice
@ast
Normal B lymphocyte developmen ...... ine phosphatase-deficient mice
@en
Normal B lymphocyte developmen ...... ine phosphatase-deficient mice
@nl
type
label
Normal B lymphocyte developmen ...... ine phosphatase-deficient mice
@ast
Normal B lymphocyte developmen ...... ine phosphatase-deficient mice
@en
Normal B lymphocyte developmen ...... ine phosphatase-deficient mice
@nl
prefLabel
Normal B lymphocyte developmen ...... ine phosphatase-deficient mice
@ast
Normal B lymphocyte developmen ...... ine phosphatase-deficient mice
@en
Normal B lymphocyte developmen ...... ine phosphatase-deficient mice
@nl
P2093
P50
P3181
P1433
P1476
Normal B lymphocyte developmen ...... ine phosphatase-deficient mice
@en
P2093
A. Wakeham
K. Kishihara
M. L. Thomas
P. S. Ohashi
T. M. Kündig
V. A. Wallace
P304
P3181
P356
10.1016/0092-8674(93)90302-7
P407
P577
1993-07-16T00:00:00Z