Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum
about
Mutations in the cilia gene ARL13B lead to the classical form of Joubert syndromeProspects for Improving Brain Function in Individuals with Down SyndromeInteraction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signallingA small-molecule smoothened agonist prevents glucocorticoid-induced neonatal cerebellar injuryThe transcription factor Zfp423/OAZ is required for cerebellar development and CNS midline patterning.Congenital hypoplasia of the cerebellum: developmental causes and behavioral consequencesThe Engrailed homeobox genes determine the different foliation patterns in the vermis and hemispheres of the mammalian cerebellum.Timing neurogenesis and differentiation: insights from quantitative clonal analyses of cerebellar granule cellsZfp423 is required for normal cerebellar development.Rab and Arf proteins in genetic diseasesSonic hedgehog signaling in the development of the mouse hypothalamusRole of Nuclear Receptors in Central Nervous System Development and Associated Diseasesβ-Catenin is critical for cerebellar foliation and laminationTrps1 and its target gene Sox9 regulate epithelial proliferation in the developing hair follicle and are associated with hypertrichosisAltered cerebellar development in nuclear receptor TAK1/ TR4 null mice is associated with deficits in GLAST(+) glia, alterations in social behavior, motor learning, startle reactivity, and microgliaCerebellar cortical lamination and foliation require cyclin A2Mouse model reveals the role of RERE in cerebellar foliation and the migration and maturation of Purkinje cellsLIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellumTransposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum developmentTalpid3-binding centrosomal protein Cep120 is required for centriole duplication and proliferation of cerebellar granule neuron progenitorsThe Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse developmentA robust and high-throughput Cre reporting and characterization system for the whole mouse brainAbnormalities in brain structure and behavior in GSK-3alpha mutant micePrimary cilia are required for cerebellar development and Shh-dependent expansion of progenitor pool.Cerebellar zonal patterning relies on Purkinje cell neurotransmission.FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellumThe p53 inhibitor MDM2 facilitates Sonic Hedgehog-mediated tumorigenesis and influences cerebellar foliationTransventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development.Preterm delivery disrupts the developmental program of the cerebellum.Wnt signaling inhibits adrenal steroidogenesis by cell-autonomous and non-cell-autonomous mechanisms.PEX13 deficiency in mouse brain as a model of Zellweger syndrome: abnormal cerebellum formation, reactive gliosis and oxidative stress.Cellular commitment in the developing cerebellumInflammation and Gli2 suppress gastrin gene expression in a murine model of antral hyperplasiaMultiple developmental programs are altered by loss of Zic1 and Zic4 to cause Dandy-Walker malformation cerebellar pathogenesis.A role for Zic1 and Zic2 in Myf5 regulation and somite myogenesis.Glucocorticoid treatment of MCMV infected newborn mice attenuates CNS inflammation and limits deficits in cerebellar development.Lhx6 and Lhx8 coordinately induce neuronal expression of Shh that controls the generation of interneuron progenitors.Growth and differentiation factor 10 (Gdf10) is involved in Bergmann glial cell development under Shh regulation.Thyroid hormone regulates the expression of the sonic hedgehog signaling pathway in the embryonic and adult Mammalian brain.A Sonic hedgehog (Shh) response deficit in trisomic cells may be a common denominator for multiple features of Down syndrome
P2860
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P2860
Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum
description
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Juni 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/06/15)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/06/15)
@nl
наукова стаття, опублікована в червні 2004
@uk
مقالة علمية (نشرت في 15-6-2004)
@ar
name
Sonic hedgehog signaling is re ...... erning of the mouse cerebellum
@ast
Sonic hedgehog signaling is re ...... erning of the mouse cerebellum
@en
Sonic hedgehog signaling is re ...... erning of the mouse cerebellum
@nl
type
label
Sonic hedgehog signaling is re ...... erning of the mouse cerebellum
@ast
Sonic hedgehog signaling is re ...... erning of the mouse cerebellum
@en
Sonic hedgehog signaling is re ...... erning of the mouse cerebellum
@nl
prefLabel
Sonic hedgehog signaling is re ...... erning of the mouse cerebellum
@ast
Sonic hedgehog signaling is re ...... erning of the mouse cerebellum
@en
Sonic hedgehog signaling is re ...... erning of the mouse cerebellum
@nl
P2093
P3181
P1476
Sonic hedgehog signaling is re ...... erning of the mouse cerebellum
@en
P2093
Amel Gritli-Linde
Andreas Kottmann
Andrew P. McMahon
Paula M. Lewis
Richard Smeyne
P304
P3181
P356
10.1016/J.YDBIO.2004.03.007
P407
P577
2004-06-15T00:00:00Z