The p53 inhibitor MDM2 facilitates Sonic Hedgehog-mediated tumorigenesis and influences cerebellar foliation
about
Targeting the Hedgehog Pathway in Pediatric MedulloblastomaThe C terminus of p53 regulates gene expression by multiple mechanisms in a target- and tissue-specific manner in vivop63 Sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signalingHDM2 promotes WIP1-mediated medulloblastoma growth.Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomasCerebellum Development and Tumorigenesis: A p53-Centric Perspective.Differential timing of granule cell production during cerebellum development underlies generation of the foliation patternEvasion of cell senescence in SHH medulloblastoma.Inhibition of the CyclinD1 promoter in response to sonic hedgehog signaling pathway transduction is mediated by Gli1The clinicopathological significance and relationship of Gli1, MDM2 and p53 expression in resectable pancreatic cancer.PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress.Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation.Intracranial undifferentiated malign neuroglial tumor in Smith-Lemli-Opitz syndrome: A theory of a possible predisposing factor for primary brain tumors via a case report.p53 in the CNS: Perspectives on Development, Stem Cells, and Cancer.Mutations in Lyar and p53 are synergistically lethal in female mice.Genipin suppresses colorectal cancer cells by inhibiting the Sonic Hedgehog pathway.Sonic hedgehog from pharyngeal arch 1 epithelium is necessary for early mandibular arch cell survival and later cartilage condensation differentiation.
P2860
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P2860
The p53 inhibitor MDM2 facilitates Sonic Hedgehog-mediated tumorigenesis and influences cerebellar foliation
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The p53 inhibitor MDM2 facilit ...... nfluences cerebellar foliation
@ast
The p53 inhibitor MDM2 facilit ...... nfluences cerebellar foliation
@en
type
label
The p53 inhibitor MDM2 facilit ...... nfluences cerebellar foliation
@ast
The p53 inhibitor MDM2 facilit ...... nfluences cerebellar foliation
@en
prefLabel
The p53 inhibitor MDM2 facilit ...... nfluences cerebellar foliation
@ast
The p53 inhibitor MDM2 facilit ...... nfluences cerebellar foliation
@en
P2093
P2860
P1433
P1476
The p53 inhibitor MDM2 facilit ...... nfluences cerebellar foliation
@en
P2093
Jennifer Matta
Mary Ellen Perry
Natalie Taylor
Reem Malek
Susan M Mendrysa
P2860
P304
P356
10.1371/JOURNAL.PONE.0017884
P407
P577
2011-03-18T00:00:00Z