Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development
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Genetics of human neural tube defectsMyristoylated Naked2 antagonizes Wnt-beta-catenin activity by degrading Dishevelled-1 at the plasma membraneMutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathwaysPlanar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytesReview series: The cell biology of hearingWnt/ß-catenin signalling and the dynamics of fate decisions in early mouse embryos and embryonic stem (ES) cellsA balance of form and function: planar polarity and development of the vestibular maculaePlanar cell polarity signaling pathway in congenital heart diseasesMolecular mechanisms of inner ear developmentComparison of phenotypes between different vangl2 mutants demonstrates dominant effects of the Looptail mutation during hair cell developmentNodal dependent differential localisation of dishevelled-2 demarcates regions of differing cell behaviour in the visceral endodermIQGAP1 functions as a modulator of dishevelled nuclear localization in Wnt signalingPlanar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary ciliaDishevelled stabilization by the ciliopathy protein Rpgrip1l is essential for planar cell polarityPax2 contributes to inner ear patterning and optic nerve trajectorySec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closureThe novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear.Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processesIdentification of neuroglobin-interacting proteins using yeast two-hybrid screeningPosterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streakLoss of Dact1 disrupts planar cell polarity signaling by altering dishevelled activity and leads to posterior malformation in miceRole of chromatin remodeling gene Cecr2 in neurulation and inner ear developmentThe small GTPase Rac1 regulates auditory hair cell morphogenesis.Making sense of Wnt signaling-linking hair cell regeneration to development.Genetics of auditory mechano-electrical transduction.PTK7 is essential for polarized cell motility and convergent extension during mouse gastrulation.Linking genes underlying deafness to hair-bundle development and function.Planar cell polarity enables posterior localization of nodal cilia and left-right axis determination during mouse and Xenopus embryogenesis.Testin interacts with vangl2 genetically to regulate inner ear sensory cell orientation and the normal development of the female reproductive tract in mice.Regulation of convergence and extension movements during vertebrate gastrulation by the Wnt/PCP pathway.Neural tube defects: recent advances, unsolved questions, and controversies.Dishevelled Paralogs in Vertebrate Development: Redundant or Distinct?Dishevelled-KSRP complex regulates Wnt signaling through post-transcriptional stabilization of beta-catenin mRNA.Gipc1 has a dual role in Vangl2 trafficking and hair bundle integrity in the inner ear.Regulation of cell fate and patterning in the developing mammalian cochlea.Loss of Dishevelleds disrupts planar polarity in ependymal motile cilia and results in hydrocephalus.Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer.Null and hypomorph Prickle1 alleles in mice phenocopy human Robinow syndrome and disrupt signaling downstream of Wnt5aDeletion of Porcn in mice leads to multiple developmental defects and models human focal dermal hypoplasia (Goltz syndrome)Hey1 and Hey2 control the spatial and temporal pattern of mammalian auditory hair cell differentiation downstream of Hedgehog signaling
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P248
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P2860
Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development
description
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im November 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/11/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/11/01)
@nl
наукова стаття, опублікована в листопаді 2008
@uk
مقالة علمية (نشرت في نوفمبر 2008)
@ar
name
Murine dishevelled 3 functions ...... a, and neural tube development
@ast
Murine dishevelled 3 functions ...... a, and neural tube development
@en
Murine dishevelled 3 functions ...... a, and neural tube development
@nl
type
label
Murine dishevelled 3 functions ...... a, and neural tube development
@ast
Murine dishevelled 3 functions ...... a, and neural tube development
@en
Murine dishevelled 3 functions ...... a, and neural tube development
@nl
prefLabel
Murine dishevelled 3 functions ...... a, and neural tube development
@ast
Murine dishevelled 3 functions ...... a, and neural tube development
@en
Murine dishevelled 3 functions ...... a, and neural tube development
@nl
P2093
P2860
P921
P3181
P1433
P1476
Murine dishevelled 3 functions ...... a, and neural tube development
@en
P2093
Daniel J. Sussman
Jianbo Wang
Nardos Lijam
Natalie Kardos
Natasha S. Hamblet
S. Leah Etheridge
Saugata Ray
Shuangding Li
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1000259
P577
2008-11-01T00:00:00Z