Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development
about
Regulation of immune cell development through soluble inositol-1,3,4,5-tetrakisphosphateIdentification of mitogen-activated protein kinase docking sites in enzymes that metabolize phosphatidylinositols and inositol phosphates.A new calmodulin-binding motif for inositol 1,4,5-trisphosphate 3-kinase regulationInositol 1,4,5-trisphosphate 3-kinases: functions and regulationsThe regulation and function of inositol 1,4,5-trisphosphate 3-kinasesInositol (1,4,5) trisphosphate 3 kinase B controls positive selection of T cells and modulates Erk activityInositol trisphosphate 3-kinase B (InsP3KB) as a physiological modulator of myelopoiesisIP3 3-kinase opposes NGF driven neurite outgrowthInositol 1,3,4,5-tetrakisphosphate controls proapoptotic Bim gene expression and survival in B cells.Normal thyroid structure and function in rhophilin 2-deficient mice.Lipid signaling in T-cell development and functionThe TAF5L gene on chromosome 1q42 is associated with type 1 diabetes in Russian affected patients.Calmodulin and PI(3,4,5)P₃ cooperatively bind to the Itk pleckstrin homology domain to promote efficient calcium signaling and IL-17A production.In silico modeling of Itk activation kinetics in thymocytes suggests competing positive and negative IP4 mediated feedbacks increase robustness.Itk: the rheostat of the T cell response.IP3 3-kinase B controls hematopoietic stem cell homeostasis and prevents lethal hematopoietic failure in miceRoles for inositol polyphosphate kinases in the regulation of nuclear processes and developmental biologyInhibition of the Inositol Kinase Itpkb Augments Calcium Signaling in Lymphocytes and Reveals a Novel Strategy to Treat Autoimmune DiseasePhosphoinositide and inositol phosphate analysis in lymphocyte activationAlterations in an inositol phosphate code through synergistic activation of a G protein and inositol phosphate kinasesComparison of predicted and actual consequences of missense mutations.Commitment issues: linking positive selection signals and lineage diversification in the thymus.Inositol tetrakisphosphate limits NK cell effector functions by controlling PI3K signalingNon-canonical antagonism of PI3K by the kinase Itpkb delays thymocyte β-selection and renders it Notch-dependent.Molecular genetics of Kawasaki disease.Defining signal transduction by inositol phosphates.Role of inositol poly-phosphatases and their targets in T cell biology.Molecular control of PtdIns(3,4,5)P3 signaling in neutrophils.Lipid and Protein Co-Regulation of PI3K Effectors Akt and Itk in Lymphocytes.Inositol trisphosphate 3-kinase B is increased in human Alzheimer brain and exacerbates mouse Alzheimer pathology.Long non-coding RNAs control hematopoietic stem cell function.Inositol-Triphosphate 3-Kinase C Mediates Inflammasome Activation and Treatment Response in Kawasaki Disease.Inositol 1,3,4,5-tetrakisphosphate negatively regulates phosphatidylinositol-3,4,5- trisphosphate signaling in neutrophils.A role for rat inositol polyphosphate kinases rIPK2 and rIPK1 in inositol pentakisphosphate and inositol hexakisphosphate production in rat-1 cells.A molecular basis for inositol polyphosphate synthesis in Drosophila melanogaster.Regulation of NGF-driven neurite outgrowth by Ins(1,4,5)P3 kinase is specifically associated with the two isoenzymes Itpka and Itpkb in a model of PC12 cells.Human inositol 1,4,5-trisphosphate 3-kinase isoform B (IP3KB) is a nucleocytoplasmic shuttling protein specifically enriched at cortical actin filaments and at invaginations of the nuclear envelope.Differential regulation of immune responses and macrophage/neuron interactions in the dorsal root ganglion in young and adult rats following nerve injury.Antiproliferative plant and synthetic polyphenolics are specific inhibitors of vertebrate inositol-1,4,5-trisphosphate 3-kinases and inositol polyphosphate multikinase.Interaction of the catalytic domain of inositol 1,4,5-trisphosphate 3-kinase A with inositol phosphate analogues.
P2860
Q24631587-2219D72C-2B3D-44A8-AA3E-B75254A4307AQ25255706-FE491F13-0BFE-4E03-BB4F-AD77BE7FC2BFQ27694737-B87A1B9D-1694-467C-AE6B-004D0C545296Q28237535-B99FD31F-9AD3-4A96-934F-94F3E0200F96Q28253119-74D672FB-98B0-449E-B13E-4FAD8799A02EQ28512312-2D6BB57F-B99D-49FB-B3E7-80C407B6A5ECQ28586246-59C7E229-824F-4F59-AFEB-F88404A5D97EQ28731851-58526090-DC8F-4E8E-933B-A7BA650D70FDQ30479990-58CB2B78-08F1-4223-9F57-D186DAE857F5Q31153741-9A4E6664-D295-45FF-B36D-2E92DA10A910Q34241131-0BD14C9F-2923-44CF-B194-F0F51CAF299FQ34457076-294B4CA1-0AD5-42C8-BAFC-8062C5A59702Q34724853-916D16BA-D116-4D74-9F66-7C130E047453Q34997154-2D8D0974-DE67-456A-932B-36CD916C8841Q35049534-9138F243-AD11-4DFE-AA55-9EC5A3D7B666Q35560031-6279A3A5-4962-4D00-B2B7-1F52F5077A4DQ35671913-7D96EDF8-FBF9-49EA-B0E0-F50595D2B602Q35677341-3A682C3B-7D3E-4D62-A45D-E82468125DC3Q35846615-DE993F87-976D-4811-AA28-1CC04AE35CEFQ36013418-07DB7AA9-79EA-4FFC-8E95-80BD5E828A8EQ36079003-ABBC55F6-D0A5-44B1-A408-961CA8B30B16Q36382781-E36988F8-6D15-42AF-8A12-23C15D4EF5F7Q36529486-05519E0B-CE2D-4812-9EA0-E15690E8980FQ36610031-C1748BB8-BB3E-4ABE-80D7-7C8968A73BACQ37384666-94059DB8-339C-420C-AC9E-DDB3BF025CFCQ37989042-13B6FC81-00A0-432F-9742-F546D07B2A49Q38143834-9EB4AB2B-CE9A-451A-A7EB-0943D8119B63Q38313393-935E4E0E-729E-46E7-B9BE-502D29060A0DQ38395493-9BAAB70A-462D-4539-88BD-E599BF01B77CQ39036400-6E601D1A-8EC4-4E70-AF3C-44E5F68C3955Q39356241-18CF5711-5267-4061-A13D-989F73BF85E3Q40086687-B458F1F9-340B-4C60-8488-5928B06CEF7DQ40325777-3FE7ED56-7913-47BC-AA25-F9927B682862Q40495561-FBC1EF6D-0CA5-43E0-A067-D45E5C972539Q40523601-733C6087-3E95-4787-BC80-A25C8C548E0DQ41041969-539FC17A-CB69-4364-BCD1-21287C9DE894Q41814062-138F3952-97F7-495A-86BE-AA4EB6E170E0Q42945808-F52EF577-07C8-4B01-BB89-94AF0FBF8E20Q45230466-E80ACF7D-B853-4624-812B-2A57B6D56EDDQ46583505-2C80C06F-600C-47B7-9C3E-23BA6B979E1A
P2860
Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development
description
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im November 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/11/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/11/01)
@nl
наукова стаття, опублікована в листопаді 2003
@uk
مقالة علمية (نشرت في نوفمبر 2003)
@ar
name
Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development
@ast
Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development
@en
Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development
@nl
type
label
Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development
@ast
Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development
@en
Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development
@nl
prefLabel
Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development
@ast
Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development
@en
Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development
@nl
P2093
P2860
P921
P356
P1433
P1476
Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development
@en
P2093
Bernard Pajak
Christophe Erneux
Emmanuelle Adam
Françoise Bex
Oberdan Leo
Romana Hascakova-Bartova
Stéphane Schurmans
Valérie Dewaste
Valérie Pouillon
P2860
P304
P356
10.1038/NI980
P407
P577
2003-11-01T00:00:00Z