Concomitant loss of proapoptotic BH3-only Bcl-2 antagonists Bik and Bim arrests spermatogenesis
about
TMEM203 Is a Novel Regulator of Intracellular Calcium Homeostasis and Is Required for SpermatogenesisPuma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis inductionRegulation of Bim in Health and DiseaseOverexpression of peroxisomal testis-specific 1 protein induces germ cell apoptosis and leads to infertility in male micePuma and Trail/Dr5 pathways control radiation-induced apoptosis in distinct populations of testicular progenitorsMaternal exposure to polycyclic aromatic hydrocarbons diminishes murine ovarian reserve via induction of HarakiriIdentification of a candidate alternative promoter region of the human Bcl2L11 (Bim) geneMale germ cell apoptosis: regulation and biology.BIK, the founding member of the BH3-only family proteins: mechanisms of cell death and role in cancer and pathogenic processes.Individual and overlapping roles of BH3-only proteins Bim and Bad in apoptosis of lymphocytes and platelets and in suppression of thymic lymphoma developmentPro-apoptotic BIM is an essential initiator of physiological endothelial cell death independent of regulation by FOXO3.The essential role of evasion from cell death in cancer.Regulation of memory B-cell survival by the BH3-only protein Puma.Star-PAP control of BIK expression and apoptosis is regulated by nuclear PIPKIα and PKCδ signaling.Bim and Bmf in tissue homeostasis and malignant disease.NBK/BIK antagonizes MCL-1 and BCL-XL and activates BAK-mediated apoptosis in response to protein synthesis inhibition.Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis.Two miRNA clusters, Mir-17-92 (Mirc1) and Mir-106b-25 (Mirc3), are involved in the regulation of spermatogonial differentiation in mice.Bcl-2 family member Bcl-G is not a proapoptotic protein.Proapoptotic BH3-only protein Bim is essential for developmentally programmed death of germinal center-derived memory B cells and antibody-forming cellsThe BH3-only proteins Bim and Puma cooperate to impose deletional tolerance of organ-specific antigens.BH3-only proteins in cell death initiation, malignant disease and anticancer therapy.BCR-signaling-induced cell death demonstrates dependency on multiple BH3-only proteins in a murine model of B-cell lymphoma.Loss of the BH3-only protein Bmf impairs B cell homeostasis and accelerates gamma irradiation-induced thymic lymphoma development.Follistatin-like 3 (FSTL3) mediated silencing of transforming growth factor β (TGFβ) signaling is essential for testicular aging and regulating testis sizeLoss of BH3-only protein Bim inhibits apoptosis of hemopoietic cells in the fetal liver and male germ cells but not neuronal cells in bcl-x-deficient miceWhat do we know about the mechanisms of elimination of autoreactive T and B cells and what challenges remain.Two-step oligoclonal development of male germ cells.Integrative epigenomic analysis reveals unique epigenetic signatures involved in unipotency of mouse female germline stem cellsTargeted Disruption of miR-17-92 Impairs Mouse Spermatogenesis by Activating mTOR Signaling Pathway.Sertoli cell Dicer is essential for spermatogenesis in mice.Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasisEnhanced stability of Mcl1, a prosurvival Bcl2 relative, blunts stress-induced apoptosis, causes male sterility, and promotes tumorigenesis.Targeting the BCL-2 family in malignancies of germinal centre origin.Deregulated cell death and lymphocyte homeostasis cause premature lethality in mice lacking the BH3-only proteins Bim and Bmf.In vivo contributions of BH3-only proteins to neuronal death following seizures, ischemia, and traumatic brain injury.Bim: guardian of tissue homeostasis and critical regulator of the immune system, tumorigenesis and bone biology.Deciphering the rules of programmed cell death to improve therapy of cancer and other diseasesThe emerging role of matrix metalloproteases of the ADAM family in male germ cell apoptosis.Small noncoding RNAs and male infertility.
P2860
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P2860
Concomitant loss of proapoptotic BH3-only Bcl-2 antagonists Bik and Bim arrests spermatogenesis
description
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im November 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/11/16)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/11/16)
@nl
наукова стаття, опублікована в листопаді 2005
@uk
مقالة علمية (نشرت في 16-11-2005)
@ar
name
Concomitant loss of proapoptot ...... nd Bim arrests spermatogenesis
@ast
Concomitant loss of proapoptot ...... nd Bim arrests spermatogenesis
@en
Concomitant loss of proapoptot ...... nd Bim arrests spermatogenesis
@nl
type
label
Concomitant loss of proapoptot ...... nd Bim arrests spermatogenesis
@ast
Concomitant loss of proapoptot ...... nd Bim arrests spermatogenesis
@en
Concomitant loss of proapoptot ...... nd Bim arrests spermatogenesis
@nl
prefLabel
Concomitant loss of proapoptot ...... nd Bim arrests spermatogenesis
@ast
Concomitant loss of proapoptot ...... nd Bim arrests spermatogenesis
@en
Concomitant loss of proapoptot ...... nd Bim arrests spermatogenesis
@nl
P2093
P2860
P50
P921
P3181
P356
P1433
P1476
Concomitant loss of proapoptot ...... nd Bim arrests spermatogenesis
@en
P2093
Harris Perlman
Leigh Coultas
Sarah Meachem
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7600857
P407
P577
2005-11-03T00:00:00Z