The transcription factors GATA4 and dHAND physically interact to synergistically activate cardiac gene expression through a p300-dependent mechanism
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Hairy-related transcription factors inhibit GATA-dependent cardiac gene expression through a signal-responsive mechanismThe Kruppel-like transcription factor KLF13 is a novel regulator of heart developmentMEF2-dependent recruitment of the HAND1 transcription factor results in synergistic activation of target promotersDifferential regulation of Hand1 homodimer and Hand1-E12 heterodimer activity by the cofactor FHL2Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growthConditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell developmentExtracellular signal-regulated kinase 2 interacts with and is negatively regulated by the LIM-only protein FHL2 in cardiomyocytesGATA- and Smad1-dependent enhancers in the Smad7 gene differentially interpret bone morphogenetic protein concentrationsOf mice and men: molecular genetics of congenital heart diseaseThe interaction between dHAND and Arix at the dopamine beta-hydroxylase promoter region is independent of direct dHAND binding to DNATranscription factor Ets1 regulates expression of thioredoxin-interacting protein and inhibits insulin secretion in pancreatic β-cellsHand2 determines the noradrenergic phenotype in the mouse sympathetic nervous systemGATA-4 is a nuclear mediator of mechanical stretch-activated hypertrophic programCurcumin prevents and reverses murine cardiac hypertrophyThe transcriptional coactivator p300 plays a critical role in the hypertrophic and protective pathways induced by phenylephrine in cardiac cells but is specific to the hypertrophic effect of urocortinRegulation of cardiomyocyte hypertrophy in diabetes at the transcriptional levelCooperative interaction between the basic helix-loop-helix transcription factor dHAND and myocyte enhancer factor 2C regulates myocardial gene expressionThe basic helix-loop-helix factor Hand 2 regulates autonomic nervous system developmentPIAS1 is a GATA4 SUMO ligase that regulates GATA4-dependent intestinal promoters independent of SUMO ligase activity and GATA4 sumoylation.Integration of CREB and bHLH transcriptional signaling pathways through direct heterodimerization of the proteins: role in muscle and testis development.Chromatin remodeling pathways in smooth muscle cell differentiation, and evidence for an integral role for p300.Inhibition of cardiomyocyte hypertrophy by protein arginine methyltransferase 5Hand2 ensures an appropriate environment for cardiac fusion by limiting Fibronectin functionGATA-4, GATA-5, and GATA-6 activate the rat liver fatty acid binding protein gene in concert with HNF-1alpha.Epigenetic regulation of cardiac myocyte differentiation.Dynamic GATA4 enhancers shape the chromatin landscape central to heart development and disease.Caffeine exposure alters cardiac gene expression in embryonic cardiomyocytes.A threshold of GATA4 and GATA6 expression is required for cardiovascular developmentMyoR modulates cardiac conduction by repressing Gata4.Art27 interacts with GATA4, FOG2 and NKX2.5 and is a novel co-repressor of cardiac genesManduca sexta moricin promoter elements can increase promoter activities of Drosophila melanogaster antimicrobial peptide genes.Forward Programming of Cardiac Stem Cells by Homogeneous Transduction with MYOCD plus TBX5cAMP induces hypertrophy and alters DNA methylation in HL-1 cardiomyocytes.Vascular smooth muscle cell phenotypic plasticity: focus on chromatin remodelling.Testosterone negatively regulates right ventricular load stress responses in mice.Role of the GATA family of transcription factors in endocrine development, function, and diseaseGATA4 is a direct transcriptional activator of cyclin D2 and Cdk4 and is required for cardiomyocyte proliferation in anterior heart field-derived myocardium.Up-Regulation of miRNA-21 Expression Promotes Migration and Proliferation of Sca-1+ Cardiac Stem Cells in Mice.A twist of insight - the role of Twist-family bHLH factors in development.GATA factors promote ER integrity and β-cell survival and contribute to type 1 diabetes risk.
P2860
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P248
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P2860
The transcription factors GATA4 and dHAND physically interact to synergistically activate cardiac gene expression through a p300-dependent mechanism
description
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2002
@ast
im Juli 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/07/05)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/07/05)
@nl
наукова стаття, опублікована в липні 2002
@uk
name
The transcription factors GATA ...... ugh a p300-dependent mechanism
@ast
The transcription factors GATA ...... ugh a p300-dependent mechanism
@en
The transcription factors GATA ...... ugh a p300-dependent mechanism
@nl
type
label
The transcription factors GATA ...... ugh a p300-dependent mechanism
@ast
The transcription factors GATA ...... ugh a p300-dependent mechanism
@en
The transcription factors GATA ...... ugh a p300-dependent mechanism
@nl
prefLabel
The transcription factors GATA ...... ugh a p300-dependent mechanism
@ast
The transcription factors GATA ...... ugh a p300-dependent mechanism
@en
The transcription factors GATA ...... ugh a p300-dependent mechanism
@nl
P2860
P3181
P356
P1476
The transcription factors GATA ...... ugh a p300-dependent mechanism
@en
P2093
Bruce E Markham
Peter Cserjesi
P2860
P304
24390-24398
P3181
P356
10.1074/JBC.M202490200
P407
P577
2002-05-06T00:00:00Z