Hand2 determines the noradrenergic phenotype in the mouse sympathetic nervous system
about
Downregulation of Dlx5 and Dlx6 expression by Hand2 is essential for initiation of tongue morphogenesisNfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failureTargeted deletion of Hand2 in cardiac neural crest-derived cells influences cardiac gene expression and outflow tract developmentBMP signaling regulates sympathetic nervous system development through Smad4-dependent and -independent pathwaysTranscription factor AP-2β regulates the neurotransmitter phenotype and maturation of chromaffin cellsHand2 is required in the epithelium for palatogenesis in miceA Tlx2-Cre mouse line uncovers essential roles for hand1 in extraembryonic and lateral mesoderm.Analysis of the Hand1 cell lineage reveals novel contributions to cardiovascular, neural crest, extra-embryonic, and lateral mesoderm derivativesCytokines inhibit norepinephrine transporter expression by decreasing Hand2Twist1 controls a cell-specification switch governing cell fate decisions within the cardiac neural crestThe transcription factor Hmx1 and growth factor receptor activities control sympathetic neurons diversification.Ascl1 as a novel player in the Ptf1a transcriptional network for GABAergic cell specification in the retina.Expression level of Hand2 affects specification of enteric neurons and gastrointestinal function in mice.Targeted deletion of Hand2 in enteric neural precursor cells affects its functions in neurogenesis, neurotransmitter specification and gangliogenesis, causing functional aganglionosis.A Phox2- and Hand2-dependent Hand1 cis-regulatory element reveals a unique gene dosage requirement for Hand2 during sympathetic neurogenesis.Target-dependent inhibition of sympathetic neuron growth via modulation of a BMP signaling pathwayRegulation of the noradrenaline neurotransmitter phenotype by the transcription factor AP-2betaConditional deletion of Hand2 reveals critical functions in neurogenesis and cell type-specific gene expression for development of neural crest-derived noradrenergic sympathetic ganglion neuronsTranscriptomic analyses of Hand2 transgenic embryos.Transcription factor GATA-3 regulates the transcriptional activity of dopamine beta-hydroxylase by interacting with Sp1 and AP4A twist of insight - the role of Twist-family bHLH factors in development.The bHLH transcription factor Hand2 is essential for the maintenance of noradrenergic properties in differentiated sympathetic neurons.Autonomic cardiac innervation: development and adult plasticity.Hand factors as regulators of cardiac morphogenesis and implications for congenital heart defectsTranscriptional control of differentiation and neurogenesis in autonomic ganglia.Ontogeny of cardiac sympathetic innervation and its implications for cardiac disease.Signaling molecules and transcription factors involved in the development of the sympathetic nervous system, with special emphasis on the superior cervical ganglion.Segregation of neuronal and neuroendocrine differentiation in the sympathoadrenal lineage.Zebrafish as a systems toxicology model for developmental neurotoxicity testing.The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells.Loss of Hand2 in a population of Periostin lineage cells results in pronounced bradycardia and neonatal deathMouse models of Hirschsprung disease and other developmental disorders of the enteric nervous system: Old and new players.Advances in understanding functional variations in the Hirschsprung disease spectrum (variant Hirschsprung disease).HAND transcription factors are required for neonatal sympathetic neuron survival.Preaxial polydactyly: interactions among ETV, TWIST1 and HAND2 control anterior-posterior patterning of the limb.Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA.Distinct roles of hand2 in developing and adult autonomic neurons.Significant transcriptional changes in 15q duplication but not Angelman syndrome deletion stem cell-derived neurons.Part and Parcel of the Cardiac Autonomic Nerve System: Unravelling Its Cellular Building Blocks during Development.From proliferation to target innervation: signaling molecules that direct sympathetic nervous system development.
P2860
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P2860
Hand2 determines the noradrenergic phenotype in the mouse sympathetic nervous system
description
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im Juli 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/07/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/07/01)
@nl
наукова стаття, опублікована в липні 2007
@uk
مقالة علمية (نشرت في يوليو 2007)
@ar
name
Hand2 determines the noradrenergic phenotype in the mouse sympathetic nervous system
@ast
Hand2 determines the noradrenergic phenotype in the mouse sympathetic nervous system
@en
Hand2 determines the noradrenergic phenotype in the mouse sympathetic nervous system
@nl
type
label
Hand2 determines the noradrenergic phenotype in the mouse sympathetic nervous system
@ast
Hand2 determines the noradrenergic phenotype in the mouse sympathetic nervous system
@en
Hand2 determines the noradrenergic phenotype in the mouse sympathetic nervous system
@nl
prefLabel
Hand2 determines the noradrenergic phenotype in the mouse sympathetic nervous system
@ast
Hand2 determines the noradrenergic phenotype in the mouse sympathetic nervous system
@en
Hand2 determines the noradrenergic phenotype in the mouse sympathetic nervous system
@nl
P2093
P2860
P3181
P1476
Hand2 determines the noradrenergic phenotype in the mouse sympathetic nervous system
@en
P2093
Fabien D'Autréaux
Michael D. Gershon
Peter Cserjesi
Yuka Morikawa
P2860
P304
P3181
P356
10.1016/J.YDBIO.2007.04.027
P407
P577
2007-07-01T00:00:00Z