Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4
about
Human immunodeficiency virus type 1 Nef and p56lck protein-tyrosine kinase interact with a common element in CD4 cytoplasmic tailHigh-fidelity gene targeting in embryonic stem cells by using sequence replacement vectorsViral immune evasion due to persistence of activated T cells without effector functionIdentification of a novel surface protein on activated CD4+ T cells that induces contact-dependent B cell differentiation (help)Distinct expression and function of the novel mouse chemokine monocyte chemotactic protein-5 in lung allergic inflammationReconstitution of the subclass-specific expression of CD4 in thymocytes and peripheral T cells of transgenic mice: identification of a human CD4 enhancerENV-specific cytotoxic T lymphocyte responses in HIV seronegative health care workers occupationally exposed to HIV-contaminated body fluidsImplications of Epigenetic Variability within a Cell Population for "Cell Type" ClassificationPriming of CD8(+) T Cell Responses to Liver Stage Malaria Parasite AntigensTranscriptional control of CD4 and CD8 coreceptor expression during T cell developmentSubcapsular sinus macrophage fragmentation and CD169+ bleb acquisition by closely associated IL-17-committed innate-like lymphocytesYellow fever virus encephalitis: properties of the brain-associated T-cell response during virus clearance in normal and gamma interferon-deficient mice and requirement for CD4+ lymphocytesA Journey in Science: "Not Lost in Translation"Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease.Immune enhancement of skin carcinogenesis by CD4+ T cells.Redirecting human CD4+ T lymphocytes to the MHC class I-restricted melanoma antigen MAGE-A1 by TCR alphabeta gene transfer requires CD8alpha.Anti-HIV agents targeting the interaction of gp120 with the cellular CD4 receptor.Modulation of CD4(+) T cell-dependent specific cytotoxic CD8(+) T cells differentiation and proliferation by the timing of increase in the pathogen load.CD4+ T cell-derived IL-2 signals during early priming advances primary CD8+ T cell responses.Immune effectors required for hepatitis B virus clearanceSpontaneous remyelination following extensive demyelination is associated with improved neurological function in a viral model of multiple sclerosis.Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaquesCD4(+) and CD8(+) T cells make discrete contributions to demyelination and neurologic disease in a viral model of multiple sclerosisCD40 ligand-mediated interactions are involved in the generation of memory CD8(+) cytotoxic T lymphocytes (CTL) but are not required for the maintenance of CTL memory following virus infection.A central role for CD4(+) T cells and RANTES in virus-induced central nervous system inflammation and demyelinationGamma interferon production is critical for protective immunity to infection with blood-stage Plasmodium berghei XAT but neither NO production nor NK cell activation is critical.Grafting mouse brains: from neurocarcinogenesis to neurodegeneration.Roles of major histocompatibility complex class II in inducing protective immune responses to influenza vaccinationThe CD4 molecule on CD8+ T lymphocytes directly enhances the immune response to viral and cellular antigensNK cells help to induce CD8(+)-T-cell immunity against Toxoplasma gondii in the absence of CD4(+) T cells.Absence of cross-presenting cells in the salivary gland and viral immune evasion confine cytomegalovirus immune control to effector CD4 T cells.Bystander activation and anti-tumor effects of CD8+ T cells following Interleukin-2 based immunotherapy is independent of CD4+ T cell help.Altered T cell activation and development in transgenic mice expressing the HIV-1 nef geneCD4 cell surface downregulation in HIV-1 Nef transgenic mice is a consequence of intracellular sequestration.Deficient humoral responses underlie susceptibility to Toxoplasma gondii in CD4-deficient miceDevelopment of a lipopeptide-based therapeutic vaccine to treat chronic HBV infection. I. Induction of a primary cytotoxic T lymphocyte response in humans.Influenza virus-infected dendritic cells stimulate strong proliferative and cytolytic responses from human CD8+ T cells.Modulation of TCRβ surface expression during TCR revision.Impaired survival of T helper cells in the absence of CD4.Appearance of immature/transitional B cells in HIV-infected individuals with advanced disease: correlation with increased IL-7.
P2860
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P2860
Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4
description
1991 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 1991
@ast
scientific journal article
@en
vedecký článok (publikovaný 1991/09/12)
@sk
vědecký článek publikovaný v roce 1991
@cs
wetenschappelijk artikel (gepubliceerd op 1991/09/12)
@nl
наукова стаття, опублікована у вересні 1991
@uk
научни чланак (објављен 1991/09/12)
@sr
name
Normal development and functio ...... l activity in mice lacking CD4
@ast
Normal development and functio ...... l activity in mice lacking CD4
@en
Normal development and functio ...... l activity in mice lacking CD4
@nl
type
label
Normal development and functio ...... l activity in mice lacking CD4
@ast
Normal development and functio ...... l activity in mice lacking CD4
@en
Normal development and functio ...... l activity in mice lacking CD4
@nl
prefLabel
Normal development and functio ...... l activity in mice lacking CD4
@ast
Normal development and functio ...... l activity in mice lacking CD4
@en
Normal development and functio ...... l activity in mice lacking CD4
@nl
P2093
P356
P1433
P1476
Normal development and functio ...... l activity in mice lacking CD4
@en
P2093
Narendran A
Rahemtulla A
Sambhara SR
Schilham MW
Zinkernagel RM
P2888
P304
P356
10.1038/353180A0
P407
P577
1991-09-01T00:00:00Z
P6179
1037128186