Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis
about
FGFR1 is essential for prostate cancer progression and metastasisSulfatase 1 is an inhibitor of ductal morphogenesis with sexually dimorphic expression in the urogenital sinusMolecular signatures of the primitive prostate stem cell niche reveal novel mesenchymal-epithelial signaling pathwaysCellular signaling by fibroblast growth factors (FGFs) and their receptors (FGFRs) in male reproduction.Molecular signaling pathways that regulate prostate gland development.Role of FGFR2-signaling in the pathogenesis of acne.Enhanced paracrine FGF10 expression promotes formation of multifocal prostate adenocarcinoma and an increase in epithelial androgen receptorMolecular genetics of prostate cancer: new prospects for old challengesMolecular pathways and targets in prostate cancerβ-catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma.FGFR2 in the dental epithelium is essential for development and maintenance of the maxillary cervical loop, a stem cell niche in mouse incisorsGenetic regulation of prostate development.PI3K/mTOR signaling regulates prostatic branching morphogenesisBisphenol-A induces expression of HOXC6, an estrogen-regulated homeobox-containing gene associated with breast cancer.Aberrant expression of Cks1 and Cks2 contributes to prostate tumorigenesis by promoting proliferation and inhibiting programmed cell death.Neuron-derived FGF9 is essential for scaffold formation of Bergmann radial fibers and migration of granule neurons in the cerebellum.Overexpression of FGF9 in prostate epithelial cells augments reactive stroma formation and promotes prostate cancer progression.Prostate Sphere-forming Stem Cells Are Derived from the P63-expressing Basal Compartment.Type 2 Fibroblast Growth Factor Receptor Signaling Preserves Stemness and Prevents Differentiation of Prostate Stem Cells from the Basal Compartment.HOXC6 is deregulated in human head and neck squamous cell carcinoma and modulates Bcl-2 expressionWnt signaling though beta-catenin is required for prostate lineage specificationFGF coordinates air sac development by activation of the EGF ligand Vein through the transcription factor PntP2Initiation of prostate cancer in mice by Tp53R270H: evidence for an alternative molecular progression.Recent advances in prostate development and links to prostatic diseasesLoss of epithelial oestrogen receptor α inhibits oestrogen-stimulated prostate proliferation and squamous metaplasia via in vivo tissue selective knockout modelsDistinct expression patterns of Sulf1 and Hs6st1 spatially regulate heparan sulfate sulfation during prostate developmentGenetic mosaic analysis reveals FGF receptor 2 function in terminal end buds during mammary gland branching morphogenesis.Combined KIT and FGFR2b signaling regulates epithelial progenitor expansion during organogenesis.2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits fibroblast growth factor 10-induced prostatic bud formation in mouse urogenital sinusLgr4 is a key regulator of prostate development and prostate stem cell differentiation.Self-renewal and multilineage differentiation of mouse dental epithelial stem cells.FGF signalling in prostate development, tissue homoeostasis and tumorigenesis.Small-molecule protein tyrosine kinase inhibitors for the treatment of metastatic prostate cancer.Dissecting Major Signaling Pathways throughout the Development of Prostate Cancer.Targeting fibroblast growth factor pathways in prostate cancer.Disruption of prostate epithelial differentiation pathways and prostate cancer development.The molecular and cellular basis of Apert syndrome.Transcriptional regulation of MDR-1 by HOXC6 in multidrug-resistant cells.Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization.Morphoregulatory pathways in prostate ductal development.
P2860
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P2860
Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis
description
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im Januar 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/02/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/02/01)
@nl
наукова стаття, опублікована в лютому 2007
@uk
مقالة علمية (نشرت في فبراير 2007)
@ar
name
Fibroblast growth factor recep ...... y for adult tissue homeostasis
@ast
Fibroblast growth factor recep ...... y for adult tissue homeostasis
@en
Fibroblast growth factor recep ...... y for adult tissue homeostasis
@nl
type
label
Fibroblast growth factor recep ...... y for adult tissue homeostasis
@ast
Fibroblast growth factor recep ...... y for adult tissue homeostasis
@en
Fibroblast growth factor recep ...... y for adult tissue homeostasis
@nl
prefLabel
Fibroblast growth factor recep ...... y for adult tissue homeostasis
@ast
Fibroblast growth factor recep ...... y for adult tissue homeostasis
@en
Fibroblast growth factor recep ...... y for adult tissue homeostasis
@nl
P2093
P356
P1433
P1476
Fibroblast growth factor recep ...... y for adult tissue homeostasis
@en
P2093
Chunhong Lin
Guoqin Liu
Jim W Xuan
Kerstin McKeehan
Norman Greenberg
Wallace L McKeehan
Ya-Ping Hu
Yongshun Lin
P304
P356
10.1242/DEV.02765
P407
P577
2007-01-10T00:00:00Z