p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours
about
The p53 family member genes are involved in the Notch signal pathwayThe ubiquitin-protein ligase Itch regulates p73 stabilityRegulation of p73 by Hck through kinase-dependent and independent mechanismsThe F-box protein FBXO45 promotes the proteasome-dependent degradation of p73A C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism.Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domainsBrn-3a/POU4F1 interacts with and differentially affects p73-mediated transcriptionInduction of p57(KIP2) expression by p73beta.The C terminus of p53 family proteins is a cell fate determinantDNA damage in oocytes induces a switch of the quality control factor TAp63α from dimer to tetramerSplitting p63Functional association between Wwox tumor suppressor protein and p73, a p53 homologThe first 30 years of p53: growing ever more complexThe transcriptional repressor ZEB regulates p73 expression at the crossroad between proliferation and differentiationTP73 allelic expression in human brain and allele frequencies in Alzheimer's disease(-)-Gossypol acts directly on the mitochondria to overcome Bcl-2- and Bcl-X(L)-mediated apoptosis resistance.Oncogenic Intra-p53 Family Member Interactions in Human Cancersp73: a Positive or Negative Regulator of Angiogenesis, or Both?DNA repair and aging: the impact of the p53 familyNovel Implications of DNA Damage Response in Drug Resistance of Malignant Cancers Obtained from the Functional Interaction between p53 Family and RUNX2Imprinted Zac1 in neural stem cellsMouse models for human otitis mediaStructural evolution of C-terminal domains in the p53 familyStructural evolution of p53, p63, and p73: Implication for heterotetramer formationStructural Basis for ASPP2 Recognition by the Tumor Suppressor p73Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence codeCaught in the cross fire: p53 in inflammation.Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerizationEmerging Non-Canonical Functions and Regulation by p53: p53 and StemnessThe Regulation of Tumor Suppressor p63 by the Ubiquitin-Proteasome SystemA ribonucleotide reductase gene is a transcriptional target of p53 and p73Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motifP63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndromeBTG2(TIS21/PC3) induces neuronal differentiation and prevents apoptosis of terminally differentiated PC12 cellsp19ras brings a new twist to the regulation of p73 by Mdm2The p53 circuit boardE1A activates transcription of p73 and Noxa to induce apoptosisTwo molecularly distinct intracellular pathways to oligodendrocyte differentiation: role of a p53 family protein.TP53INP1 is a novel p73 target gene that induces cell cycle arrest and cell death by modulating p73 transcriptional activityAbnormal development of NG2+PDGFR-α+ neural progenitor cells leads to neonatal hydrocephalus in a ciliopathy mouse model
P2860
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P2860
p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours
description
2000 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 2000
@ast
scientific journal article
@en
vedecký článok (publikovaný 2000/03/02)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/03/02)
@nl
наукова стаття, опублікована в березні 2000
@uk
مقالة علمية (نشرت في 2-3-2000)
@ar
name
p73-deficient mice have neurol ...... s but lack spontaneous tumours
@ast
p73-deficient mice have neurol ...... s but lack spontaneous tumours
@en
p73-deficient mice have neurol ...... s but lack spontaneous tumours
@nl
type
label
p73-deficient mice have neurol ...... s but lack spontaneous tumours
@ast
p73-deficient mice have neurol ...... s but lack spontaneous tumours
@en
p73-deficient mice have neurol ...... s but lack spontaneous tumours
@nl
prefLabel
p73-deficient mice have neurol ...... s but lack spontaneous tumours
@ast
p73-deficient mice have neurol ...... s but lack spontaneous tumours
@en
p73-deficient mice have neurol ...... s but lack spontaneous tumours
@nl
P2093
P3181
P356
P1433
P1476
p73-deficient mice have neurol ...... s but lack spontaneous tumours
@en
P2093
M. Oosterwegel
P2888
P304
P3181
P356
10.1038/35003607
P407
P577
2000-03-02T00:00:00Z
P5875
P6179
1009322829