Structural evolution of C-terminal domains in the p53 family
about
The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73DNA damage in oocytes induces a switch of the quality control factor TAp63α from dimer to tetramerStructural evolution of p53, p63, and p73: Implication for heterotetramer formationMechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerizationTracing the evolution of the p53 tetramerization domainPhylogeny and function of the invertebrate p53 superfamilyRunning on empty: how p53 controls INS/IGF signaling and affects life spanTranscriptional profiling in C. elegans suggests DNA damage dependent apoptosis as an ancient function of the p53 family.Conservation of DNA-binding specificity and oligomerisation properties within the p53 family.A planarian p53 homolog regulates proliferation and self-renewal in adult stem cell lineagesThe origins and evolution of the p53 family of genes.p63 and p73, the ancestors of p53.Tracing the protectors path from the germ line to the genome.Analysis of the p53/CEP-1 regulated non-coding transcriptome in C. elegans by an NSR-seq strategy.p73 in Cancer.Evolution of p53 transactivation specificity through the lens of a yeast-based functional assaySpecial AT-rich binding protein-2 (SATB2) differentially affects disease-causing p63 mutant proteins.p53 basic C terminus regulates p53 functions through DNA binding modulation of subset of target genesEvaluating Drosophila p53 as a model system for studying cancer mutationsStructural investigations of the p53/p73 homologs from the tunicate species Ciona intestinalis reveal the sequence requirements for the formation of a tetramerization domain.The function of Drosophila p53 isoforms in apoptosis.Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level.Therapeutic prospects for p73 and p63: rising from the shadow of p53.Analysis of the oligomeric state and transactivation potential of TAp73α.Setdb1, a novel interactor of ΔNp63, is involved in breast tumorigenesisp53/CEP-1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress.Sirtuin/Sir2 phylogeny, evolutionary considerations and structural conservation.The tumor suppressor p53: from structures to drug discovery.Immunohistochemical evaluation of oral epithelial dysplasia using cyclin-D1, p27 and p63 expression as predictors of malignant transformation.How the TP53 family proteins TP63 and TP73 contribute to tumorigenesis: regulators and effectors.Maintaining epithelial stemness with p63.Structural Evolution and Dynamics of the p53 Proteins.Modification of Drosophila p53 by SUMO modulates its transactivation and pro-apoptotic functions.Dual roles of Drosophila p53 in cell death and cell differentiation.Brdm2 - an aberrant hypomorphic p63 allele.Molecular dynamics of the full-length p53 monomer.Daughters of the Enamel Organ: Development, Fate, and Function of the Stratum Intermedium, Stellate Reticulum, and Outer Enamel Epithelium.The SCF FSN-1 ubiquitin ligase controls germline apoptosis through CEP-1/p53 in C. elegans.The emergence of protein complexes: quaternary structure, dynamics and allostery. Colworth Medal Lecture.Control mechanisms in germ cells mediated by p53 family proteins.
P2860
Q24311644-75FB2B97-5FF6-49D7-8880-63ADDDBE9F06Q24600818-B304E1FF-4DDB-4895-956C-D8CF0804DB32Q27657730-B52DD4D5-B7B7-43C1-8BFD-E310CC52B04CQ27728187-D8E00F0B-4062-4A49-9EB7-7075B4109222Q28656003-A301F268-C147-46BE-9ABF-756C970A75D4Q28751278-FFB1842B-7538-41FB-B93E-99CE0EAD52E1Q30446473-57A8D9A2-B17D-496E-806C-00CB67748B5EQ33351781-06BBFEFE-4E6E-4B9F-94C1-2BDD22056B95Q33520529-960CB2C0-716C-4915-8838-0BB1CD2A82B2Q33561621-3B5EDEFB-93EB-4703-B62E-9148C6580072Q33849403-82725B31-CA48-4E02-9D2C-614738EF1EFFQ34080237-71CEDEF2-79F3-4A58-B976-7F7DFA0C7C29Q34100529-27124882-102F-4837-9515-C76E44567691Q34268888-C1A47CD8-2806-4507-8B1E-F6F7066B10F6Q35103143-F7744BDB-3887-4FD2-9D4B-79D576D4B8EAQ35558858-DA0138F9-559E-4638-B019-2B6585BECE5FQ35562528-4AF71433-7EA3-4ABD-AC6C-E9CF22D5626EQ36052576-24D83A6D-8F40-4D45-A477-FEC072D8C3B7Q36492803-4D61C49C-750D-451C-B8A6-CB7ABED3B653Q36749526-FAA06A03-D5AE-47A0-8EAE-D86A446345F2Q36751520-19E9F544-2B61-416B-AC86-99F06DA21413Q36925989-DA624180-D63F-4AA5-A280-230762D10F85Q36979908-4D721470-1FDE-4706-8653-8AA4080562CAQ36994773-8A71E10E-61A3-4D86-8D3F-D577D65EAE16Q37301684-10A2C4A1-F6B4-478C-96D1-5C733F131CF6Q37315159-2CDB2C9D-E75B-41EF-A223-DF99A7EF7340Q37638325-102785A4-6DA4-4FE1-9BF8-3C3C492694C2Q37762069-1A06A9AA-8E63-4230-B493-57D4BF58531FQ38148142-3C962B3A-C0D4-401D-8424-466D8AC8065CQ38184518-28B6C1D6-A9F7-4FB6-9C4B-EC60DC41E2D7Q38556654-D5345B7F-A7D7-4B69-8C80-B3041D4ED45CQ38811603-9B743BEE-04F3-409D-9B03-321CBB378932Q40423291-13024812-04D6-4A46-B212-FC055101C912Q41608122-51FFF1A3-EB3E-4C9D-B234-43AFCC4F3113Q41813087-7A3E638A-0332-4DDD-86C1-3898C140096AQ42103308-E575993D-B168-48EA-A12B-776D9F73C3C1Q42378863-8F93BD60-5C67-4847-8564-98497B140A61Q46702418-B7285658-70E3-4F54-A8FF-A54B0285D984Q47576146-103984F5-2A28-448F-9E52-F6F85B3CC733Q47671672-2F71A5F9-DD09-45B1-B917-7B7EA90770F8
P2860
Structural evolution of C-terminal domains in the p53 family
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Structural evolution of C-terminal domains in the p53 family
@ast
Structural evolution of C-terminal domains in the p53 family
@en
Structural evolution of C-terminal domains in the p53 family
@nl
type
label
Structural evolution of C-terminal domains in the p53 family
@ast
Structural evolution of C-terminal domains in the p53 family
@en
Structural evolution of C-terminal domains in the p53 family
@nl
prefLabel
Structural evolution of C-terminal domains in the p53 family
@ast
Structural evolution of C-terminal domains in the p53 family
@en
Structural evolution of C-terminal domains in the p53 family
@nl
P2093
P2860
P3181
P356
P1433
P1476
Structural evolution of C-terminal domains in the p53 family
@en
P2093
Horng Der Ou
Vitali Vogel
Werner Mäntele
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7601764
P407
P577
2007-07-25T00:00:00Z