The p97/VCP ATPase is critical in muscle atrophy and the accelerated degradation of muscle proteins
about
Cardiac-Restricted Expression of VCP/TER94 RNAi or Disease Alleles Perturbs Drosophila Heart Structure and Impairs Function.Histone deacetylase 6 is a FoxO transcription factor-dependent effector in skeletal muscle atrophy.Proteotoxic crisis, the ubiquitin-proteasome system, and cancer therapy.VCP-dependent muscle degeneration is linked to defects in a dynamic tubular lysosomal network in vivo.Inadequate fine-tuning of protein synthesis and failure of amino acid homeostasis following inhibition of the ATPase VCP/p97Blocking Cancer Growth with Less POMP or Proteasomes.Mutant copper-zinc superoxide dismutase (SOD1) induces protein secretion pathway alterations and exosome release in astrocytes: implications for disease spreading and motor neuron pathology in amyotrophic lateral sclerosisMechanisms of skeletal muscle aging: insights from Drosophila and mammalian modelsTrim32 reduces PI3K-Akt-FoxO signaling in muscle atrophy by promoting plakoglobin-PI3K dissociation.Protein breakdown in muscle wasting: role of autophagy-lysosome and ubiquitin-proteasomeMechanisms of muscle growth and atrophy in mammals and Drosophila.Mechanisms modulating skeletal muscle phenotype.TRAF6 inhibition rescues dexamethasone-induced muscle atrophy.Activation of the SDF1/CXCR4 pathway retards muscle atrophy during cancer cachexia.Valosin-containing protein (VCP)-Adaptor Interactions are Exceptionally Dynamic and Subject to Differential Modulation by a VCP Inhibitor.Functional phosphatome requirement for protein homeostasis, networked mitochondria, and sarcomere structure in C. elegans muscle.MicroRNA deep sequencing in two adult stem cell populations identifies miR-501 as a novel regulator of myosin heavy chain during muscle regeneration.Myofibril breakdown during atrophy is a delayed response requiring the transcription factor PAX4 and desmin depolymerization.Losing pieces without disintegrating: Contractile protein loss during muscle atrophy.Control of proteasomal proteolysis by mTORChaperoning myosin assembly in muscle formation and aging.UFD-2 is an adaptor-assisted E3 ligase targeting unfolded proteins.Group I Paks support muscle regeneration and counteract cancer-associated muscle atrophy.Micro-computed tomography for non-invasive evaluation of muscle atrophy in mouse models of disease.
P2860
Q27303589-92D30CB6-60F3-4965-A262-361DB64EF566Q35080304-DA901C9C-785D-4287-9716-0875DDF4629EQ35408665-0BDEEDC5-2520-4ACE-B83E-F8B853019FB4Q36071401-18C2DFAF-34D1-4F27-9B05-6E25A31BA821Q36485185-21AF1845-9E26-4DC5-9EDE-E4E5C593AE83Q36675932-2A2B45A9-6153-4431-B3F4-2EC49C8817DEQ36890607-57835866-16F6-49C8-A976-C6596B209488Q37287412-B1596CA3-D699-416A-8042-5B1A2EE01B82Q37614832-7834003E-86BD-4E7A-BC82-48CD2BBD5B3CQ38105829-37510714-A0C5-4EAE-8758-CB4781742AC2Q38137908-378A665C-DA66-4C93-B52A-B9A06CF18C93Q38165143-4822D65E-9883-4363-A9E9-612454881B26Q38982057-F66A5FDC-2DFA-4CF5-B290-F654B1E82326Q39745261-F864E218-D45A-488E-89D9-FC89928B7B99Q41028234-9B82DD71-326D-4AC5-A348-78A90AD1442CQ41485482-F23D3FC1-62A7-48D9-BB82-E99F8025EFE4Q41828703-58F306F7-9BCE-4369-BA64-B63E5A1DF110Q41943570-5B300875-D939-4254-A262-24A3B6A695BEQ42318146-E5011213-F945-4F9F-ABF4-D9211D40612FQ42588447-B79EE8B9-F800-4A8C-880A-4C83FB6F5494Q42770507-56D4AFB9-12DC-460C-9A72-A6EC29ACA6B7Q48113345-00F58BC4-95BA-4A43-B988-6BA5440A89F6Q54978691-7FE38FB6-FCC0-4853-859F-AE56F5D520ABQ55423762-BABC09F8-43AD-4624-BE94-65FAB834E7B6
P2860
The p97/VCP ATPase is critical in muscle atrophy and the accelerated degradation of muscle proteins
description
2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2012
@ast
im August 2012 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2012/08/01)
@sk
vědecký článek publikovaný v roce 2012
@cs
wetenschappelijk artikel (gepubliceerd op 2012/08/01)
@nl
наукова стаття, опублікована в серпні 2012
@uk
مقالة علمية (نشرت في أغسطس 2012)
@ar
name
The p97/VCP ATPase is critical ...... degradation of muscle proteins
@ast
The p97/VCP ATPase is critical ...... degradation of muscle proteins
@en
The p97/VCP ATPase is critical ...... degradation of muscle proteins
@nl
type
label
The p97/VCP ATPase is critical ...... degradation of muscle proteins
@ast
The p97/VCP ATPase is critical ...... degradation of muscle proteins
@en
The p97/VCP ATPase is critical ...... degradation of muscle proteins
@nl
prefLabel
The p97/VCP ATPase is critical ...... degradation of muscle proteins
@ast
The p97/VCP ATPase is critical ...... degradation of muscle proteins
@en
The p97/VCP ATPase is critical ...... degradation of muscle proteins
@nl
P2860
P3181
P356
P1433
P1476
The p97/VCP ATPase is critical ...... degradation of muscle proteins
@en
P2093
Alfred L. Goldberg
Rosanna Piccirillo
P2860
P304
P3181
P356
10.1038/EMBOJ.2012.178
P407
P577
2012-08-01T00:00:00Z