The Kindlins: subcellular localization and expression during murine development
about
Kindlin-2 is required for myocyte elongation and is essential for myogenesisKindlin-2 regulates podocyte adhesion and fibronectin matrix deposition through interactions with phosphoinositides and integrinsA point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humansLeukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation.Platelet proteome analysis reveals integrin-dependent aggregation defects in patients with myelodysplastic syndromes.The integrin co-activator Kindlin-3 is expressed and functional in a non-hematopoietic cell, the endothelial cell.Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effectsKindlin-3-mediated integrin adhesion is dispensable for quiescent but essential for activated hematopoietic stem cells.Metalloproteinase MT1-MMP islets act as memory devices for podosome reemergenceKindlin-1 regulates integrin dynamics and adhesion turnoverThe Structure of the N-Terminus of Kindlin-1: A Domain Important for αIIbβ3 Integrin ActivationStructural and Functional Characterization of the Kindlin-1 Pleckstrin Homology DomainKindlin-3 is required for beta2 integrin-mediated leukocyte adhesion to endothelial cellsKindlin-2 controls bidirectional signaling of integrinsKindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferationDiverse functions of kindlin/fermitin proteins during embryonic development in Xenopus laevis.Kindlin-1 Is required for RhoGTPase-mediated lamellipodia formation in keratinocytesThe integrin coactivator kindlin-2 plays a critical role in angiogenesis in mice and zebrafishKindlin-3 regulates integrin activation and adhesion reinforcement of effector T cells.Loss of Kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction.Significance of talin in cancer progression and metastasis.Direct interaction of kindlin-3 with integrin αIIbβ3 in platelets is required for supporting arterial thrombosis in mice.Differences in binding to the ILK complex determines kindlin isoform adhesion localization and integrin activationSpatial coordination of kindlin-2 with talin head domain in interaction with integrin β cytoplasmic tailsA mouse model of generalized non-Herlitz junctional epidermolysis bullosa.Kindlin 2 regulates myogenic related factor myogenin via a canonical Wnt signaling in myogenic differentiation.Podosomes and Invadopodia: Related structures with Common Protein Components that May Promote Breast Cancer Cellular Invasion.Integrins are the necessary links to hypertrophic growth in cardiomyocytesKindlin-2 expression in arsenite- and cadmium-transformed bladder cancer cell lines and in archival specimens of human bladder cancer.Emergence and subsequent functional specialization of kindlins during evolution of cell adhesiveness.Molecular identification of collagen 17a1 as a major genetic modifier of laminin gamma 2 mutation-induced junctional epidermolysis bullosa in mice.Site-specific phosphorylation of kindlin-3 protein regulates its capacity to control cellular responses mediated by integrin αIIbβ3.Peripheral blood mononuclear cell proteome changes in patients with myelodysplastic syndromeDeconstructing the skin: cytoarchitectural determinants of epidermal morphogenesisA conserved lipid-binding loop in the kindlin FERM F1 domain is required for kindlin-mediated αIIbβ3 integrin coactivation.NMR Characterization and Membrane Interactions of the Loop Region of Kindlin-3 F1 Subdomain.Cooperative Stimulation of Megakaryocytic Differentiation by Gfi1b Gene Targets Kindlin3 and Talin1IL-1β enhances cell adhesion to degraded fibronectin.Integrin associated proteins differentially regulate neutrophil polarity and directed migration in 2D and 3DKindlin-3 interacts with the ribosome and regulates c-Myc expression required for proliferation of chronic myeloid leukemia cells
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P2860
The Kindlins: subcellular localization and expression during murine development
description
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im Oktober 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/10/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/10/01)
@nl
наукова стаття, опублікована в жовтні 2006
@uk
مقالة علمية (نشرت في أكتوبر 2006)
@ar
name
The Kindlins: subcellular localization and expression during murine development
@ast
The Kindlins: subcellular localization and expression during murine development
@en
The Kindlins: subcellular localization and expression during murine development
@nl
type
label
The Kindlins: subcellular localization and expression during murine development
@ast
The Kindlins: subcellular localization and expression during murine development
@en
The Kindlins: subcellular localization and expression during murine development
@nl
prefLabel
The Kindlins: subcellular localization and expression during murine development
@ast
The Kindlins: subcellular localization and expression during murine development
@en
The Kindlins: subcellular localization and expression during murine development
@nl
P2093
P921
P3181
P1476
The Kindlins: subcellular localization and expression during murine development
@en
P2093
Hao-Ven Wang
Markus Moser
Stefan Linder
P304
P3181
P356
10.1016/J.YEXCR.2006.06.030
P407
P577
2006-10-01T00:00:00Z