Safety, pharmacokinetic, and efficacy studies of oral DB868 in a first stage vervet monkey model of human African trypanosomiasis
about
Chemotherapy of second stage human African trypanosomiasis: comparison between the parenteral diamidine DB829 and its oral prodrug DB868 in vervet monkeysSynthesis, antimicrobial, and antiproliferative activities of substituted phenylfuranylnicotinamidines.Pharmacokinetics, Trypanosoma brucei gambiense efficacy, and time of drug action of DB829, a preclinical candidate for treatment of second-stage human African trypanosomiasisDrug discovery and human African trypanosomiasis: a disease less neglected?Independence from Kinetoplast DNA maintenance and expression is associated with multidrug resistance in Trypanosoma brucei in vitro.Effect of age and sex on bone markers in Chlorocebus aethiops raised in captivity.CYP1A1 and CYP1B1-mediated biotransformation of the antitrypanosomal methamidoxime prodrug DB844 forms novel metabolites through intramolecular rearrangement.Novel lead compounds in pre-clinical development against African sleeping sickness
P2860
Q28543200-752768BD-CB30-4ED8-B1E5-F775B46AF303Q36697144-1DFD6B8E-B5FF-4FD5-8E20-F572B05BE86FQ37263574-FFFDEBFD-E0D9-41F4-8DAC-DC9B16BAD1C4Q38154344-C7918BC9-E077-40AC-B3B3-9530EF78707CQ38848911-6978BC64-9C94-4FD3-B504-A377B63F3948Q40336275-95E7F112-9B79-4346-A518-4759B6AD20A5Q42054617-AF3575D7-309E-4EDE-8DA0-66B0A2429753Q58842335-4A8D8814-0BB3-4EA1-B33E-903DCF88C0EA
P2860
Safety, pharmacokinetic, and efficacy studies of oral DB868 in a first stage vervet monkey model of human African trypanosomiasis
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Safety, pharmacokinetic, and e ...... human African trypanosomiasis
@ast
Safety, pharmacokinetic, and e ...... human African trypanosomiasis
@en
Safety, pharmacokinetic, and e ...... human African trypanosomiasis
@nl
type
label
Safety, pharmacokinetic, and e ...... human African trypanosomiasis
@ast
Safety, pharmacokinetic, and e ...... human African trypanosomiasis
@en
Safety, pharmacokinetic, and e ...... human African trypanosomiasis
@nl
prefLabel
Safety, pharmacokinetic, and e ...... human African trypanosomiasis
@ast
Safety, pharmacokinetic, and e ...... human African trypanosomiasis
@en
Safety, pharmacokinetic, and e ...... human African trypanosomiasis
@nl
P2093
P2860
P921
P1476
Safety, pharmacokinetic, and e ...... human African trypanosomiasis
@en
P2093
Arlene S Bridges
David W Boykin
Grace A Murilla
James Edwin Hall
James N Mutuku
John K Thuita
Kristina K Wolf
Mary F Paine
Michael Zhuo Wang
P2860
P356
10.1371/JOURNAL.PNTD.0002230
P407
P577
2013-01-01T00:00:00Z