FUS Interacts with HSP60 to Promote Mitochondrial Damage - Wikidata - awgldk - TriplyDB

FUS Interacts with HSP60 to Promote Mitochondrial Damage

FUS Interacts with HSP60 to Promote Mitochondrial Damage

http://www.wikidata.org/entity/Q28547727

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Dysregulated axonal RNA translation in amyotrophic lateral sclerosis Mutant TDP-43 does not impair mitochondrial bioenergetics in vitro and in vivo Abnormalities of Mitochondrial Dynamics in Neurodegenerative Diseases.TDP-43 or FUS-induced misfolded human wild-type SOD1 can propagate intercellularly in a prion-like fashion MiR-130a regulates neurite outgrowth and dendritic spine density by targeting MeCP2 A new method for quantifying mitochondrial axonal transport.Could Sirtuin Activities Modify ALS Onset and Progression?PINK1 and Parkin are genetic modifiers for FUS-induced neurodegeneration.Energy Homeostasis and Abnormal RNA Metabolism in Amyotrophic Lateral Sclerosis ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations.Mitochondrial quality control in amyotrophic lateral sclerosis: towards a common pathway?Cellular Chaperones As Therapeutic Targets in ALS to Restore Protein Homeostasis and Improve Cellular Function Roles of sigma-1 receptors on mitochondrial functions relevant to neurodegenerative diseases.FUS toxicity is rescued by the modulation of lncRNA hsrω expression in Drosophila melanogaster.Mitochondrial abnormalities and disruption of the neuromuscular junction precede the clinical phenotype and motor neuron loss in hFUSWT transgenic mice.mPOS is a novel mitochondrial trigger of cell death - implications for neurodegeneration.Amyotrophic lateral sclerosis-associated mutant SOD1 inhibits anterograde axonal transport of mitochondria by reducing Miro1 levels.Molecular determinants of cytochrome C oxidase IV mRNA axonal trafficking.Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation.Oncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2 activation during pancreatic cancer cell growth.Lymphoblastoid cell lines as a model to understand amyotrophic lateral sclerosis disease mechanisms.Amyotrophic Lateral Sclerosis associated FUS mutation shortens mitochondria and induces neurotoxicity Chaperonin 60 sustains osteoblast autophagy and counteracts glucocorticoid aggravation of osteoporosis by chaperoning RPTOR

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P2860

FUS Interacts with HSP60 to Promote Mitochondrial Damage

http://www.wikidata.org/entity/Q28547727

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2015 nî lūn-bûn

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2015 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

@zh-hans

2015年学术文章

@zh-my

2015年学术文章

@zh-sg

2015年學術文章

@yue

name

FUS Interacts with HSP60 to Promote Mitochondrial Damage

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FUS Interacts with HSP60 to Promote Mitochondrial Damage

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FUS Interacts with HSP60 to Promote Mitochondrial Damage

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type

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FUS Interacts with HSP60 to Promote Mitochondrial Damage

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FUS Interacts with HSP60 to Promote Mitochondrial Damage

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FUS Interacts with HSP60 to Promote Mitochondrial Damage

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prefLabel

FUS Interacts with HSP60 to Promote Mitochondrial Damage

@ast

FUS Interacts with HSP60 to Promote Mitochondrial Damage

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FUS Interacts with HSP60 to Promote Mitochondrial Damage

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JOURNAL.PGEN.1005357

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FUS Interacts with HSP60 to Promote Mitochondrial Damage

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Eileen H Bigio

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Haipeng Cheng

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Jane Y Wu

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Jianghong Liu

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Kazuo Fushimi

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Li Zhu

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Marsel Mesulam

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Mengxue Yang

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Qi Xu

http://www.w3.org/2001/XMLSchema#string

Shufeng Sun

http://www.w3.org/2001/XMLSchema#string

P2860

Cytosolic accumulation of HSP60 during apoptosis with or without apparent mitochondrial release: evidence that its pro-apoptotic or pro-survival functions involve differential interactions with caspase-3

Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma

Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70

Hsp60 accelerates the maturation of pro-caspase-3 by upstream activator proteases during apoptosis.

Hereditary spastic paraplegia SPG13 is associated with a mutation in the gene encoding the mitochondrial chaperonin Hsp60

Abundant FUS-immunoreactive pathology in neuronal intermediate filament inclusion disease

ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import

A new subtype of frontotemporal lobar degeneration with FUS pathology

Directional guidance of neuronal migration in the olfactory system by the protein Slit

FUS and TARDBP but not SOD1 interact in genetic models of amyotrophic lateral sclerosis

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9

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2015-09-03T00:00:00Z

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