Calpain-dependent cleavage of cain/cabin1 activates calcineurin to mediate calcium-triggered cell death.
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Calcium dysregulation links ALS defective proteins and motor neuron selective vulnerabilityProteolysis of the human DNA polymerase delta smallest subunit p12 by μ-calpain in calcium-triggered apoptotic HeLa cellsGenetic and pharmacological inhibition of calcineurin corrects the BDNF transport defect in Huntington's disease.Mechanisms of noise-induced hearing loss indicate multiple methods of prevention.Critical role of calpain-mediated cleavage of calcineurin in excitotoxic neurodegeneration.Systems analysis of circadian time-dependent neuronal epidermal growth factor receptor signaling.HPC2 and ubinuclein define a novel family of histone chaperones conserved throughout eukaryotes.Postsynaptic density-95 (PSD-95) and calcineurin control the sensitivity of N-methyl-D-aspartate receptors to calpain cleavage in cortical neurons.Conserved BK channel-protein interactions reveal signals relevant to cell death and survival.Meeting of the minds: metalloneurochemistryThe calpain/calpastatin system has opposing roles in growth and metastatic dissemination of melanoma.MFN2 couples glutamate excitotoxicity and mitochondrial dysfunction in motor neurons.The role of serine/threonine protein phosphatases in exocytosisPP2B-mediated dephosphorylation of c-Jun C terminus regulates phorbol ester-induced c-Jun/Sp1 interaction in A431 cells.Proteolytic mechanisms in necrotic cell death and neurodegeneration.Switch to glutamate receptor 2-lacking AMPA receptors increases neuronal excitability in hypothalamus and sympathetic drive in hypertension.A truncated fragment of Src protein kinase generated by calpain-mediated cleavage is a mediator of neuronal death in excitotoxicityCalpain-mediated signaling mechanisms in neuronal injury and neurodegenerationEstrogen attenuates glutamate-induced cell death by inhibiting Ca2+ influx through L-type voltage-gated Ca2+ channels.Calcium, mitochondria and apoptosis studied by fluorescence measurements.Paclitaxel induces apoptosis in breast cancer cells through different calcium--regulating mechanisms depending on external calcium conditions.Cell death mechanisms and their implications in toxicology.The calpain system and cancer.Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function.The role of glutamate in neuronal ischemic injury: the role of spark in fire.β cell ER stress and the implications for immunogenicity in type 1 diabetes.Delayed, oral pharmacological inhibition of calpains attenuates adverse post-infarction remodelling.EBV-encoded LMP-1 sensitizes nasopharyngeal carcinoma cells to genotoxic drugs by down-regulating Cabin1 expression.AM404 and VDM 11 non-specifically inhibit C6 glioma cell proliferation at concentrations used to block the cellular accumulation of the endocannabinoid anandamide.Cathepsin K knockout protects against cardiac dysfunction in diabetic mice.Environmental Factors Contribute to β Cell Endoplasmic Reticulum Stress and Neo-Antigen Formation in Type 1 Diabetes.Mitochondrial respiration is sensitive to cytoarchitectural breakdown.Gene expression analysis suggests that 1,25-dihydroxyvitamin D3 reverses experimental autoimmune encephalomyelitis by stimulating inflammatory cell apoptosis.Regulation of N-methyl-D-aspartate receptors by calpain in cortical neurons.Low-dose FK506 blocks collar-induced atherosclerotic plaque development and stabilizes plaques in ApoE-/- mice.Generation of constitutively active calcineurin by calpain contributes to delayed neuronal death following mouse brain ischemia.TNFα induces Ca2+ influx to accelerate extrinsic apoptosis in hepatocellular carcinoma cells.Effect of the knockdown of Cabin1 on p53 in glomerular podocyte.Ca2+ activation of cytosolic calpain induces the transition from apoptosis to necrosis in neutrophils with externalized phosphatidylserine.
P2860
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P2860
Calpain-dependent cleavage of cain/cabin1 activates calcineurin to mediate calcium-triggered cell death.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Calpain-dependent cleavage of ...... e calcium-triggered cell death
@nl
Calpain-dependent cleavage of ...... calcium-triggered cell death.
@ast
Calpain-dependent cleavage of ...... calcium-triggered cell death.
@en
type
label
Calpain-dependent cleavage of ...... e calcium-triggered cell death
@nl
Calpain-dependent cleavage of ...... calcium-triggered cell death.
@ast
Calpain-dependent cleavage of ...... calcium-triggered cell death.
@en
prefLabel
Calpain-dependent cleavage of ...... e calcium-triggered cell death
@nl
Calpain-dependent cleavage of ...... calcium-triggered cell death.
@ast
Calpain-dependent cleavage of ...... calcium-triggered cell death.
@en
P2093
P2860
P356
P1476
Calpain-dependent cleavage of ...... calcium-triggered cell death.
@en
P2093
Arun Bandyopadhyay
Byung Ju Kim
Chunghee Cho
Do Han Kim
Dong-Gyu Jo
Dong-Hyung Cho
Gil-Sun Hong
Ki-Woo Kim
Michael Lai
P2860
P304
P356
10.1073/PNAS.152336999
P407
P577
2002-07-11T00:00:00Z