Down-regulation of ZnT8 expression in INS-1 rat pancreatic beta cells reduces insulin content and glucose-inducible insulin secretion
about
Different role of zinc transporter 8 between type 1 diabetes mellitus and type 2 diabetes mellitusZinc and diabetes mellitus: understanding molecular mechanisms and clinical implicationsZinc transporter 8 (ZnT8) and β cell functionZinc and zinc transporter regulation in pancreatic islets and the potential role of zinc in islet transplantationZinc transporters and zinc signaling: new insights into their role in type 2 diabetesAcute cytokine-mediated downregulation of the zinc transporter ZnT8 alters pancreatic beta-cell function.The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearanceTotal zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis.TSQ (6-methoxy-8-p-toluenesulfonamido-quinoline), a common fluorescent sensor for cellular zinc, images zinc proteins.Increased DNA methylation of the SLC30A8 gene promoter is associated with type 2 diabetes in a Malay populationZinc transporter expression in zebrafish (Danio rerio) during development.The physiological role of drug transporters.Effect of zinc supplementation on insulin secretion: interaction between zinc and SLC30A8 genotype in Old Order Amish.Islet autoantigens: structure, function, localization, and regulation.Zinc transporters, mechanisms of action and therapeutic utility: implications for type 2 diabetes mellitus.Imaging trace element distributions in single organelles and subcellular featuresIn situ dimerization of multiple wild type and mutant zinc transporters in live cells using bimolecular fluorescence complementation.Zinc, pancreatic islet cell function and diabetes: new insights into an old story.Dorothy Hodgkin Lecture 2014. Understanding genes identified by genome-wide association studies for type 2 diabetes.Characterization of the human SLC30A8 promoter and intronic enhancerThe zinc transporter ZNT3 co-localizes with insulin in INS-1E pancreatic beta cells and influences cell survival, insulin secretion capacity, and ZNT8 expression.Epigenetic modification of nucleic acids: from basic studies to medical applications.A low-risk ZnT-8 allele (W325) for post-transplantation diabetes mellitus is protective against cyclosporin A-induced impairment of insulin secretion.Urinary nickel and prolactin in workers exposed to urban stressors.Tumor necrosis factor α-induced protein-3 protects zinc transporter 8 against proinflammatory cytokine-induced downregulation.Coupling of Insulin Secretion and Display of a Granule-resident Zinc Transporter ZnT8 on the Surface of Pancreatic Beta Cells.Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion.Implications of impaired zinc homeostasis in diabetic cardiomyopathy and nephropathy.Deciphering Tacrolimus-Induced Toxicity in Pancreatic β Cells.Disturbance of zinc and glucose homeostasis by methyl tert-butyl ether (MTBE); evidence for type 2 diabetes.Prediction of HLA class I-restricted T-cell epitopes of islet autoantigen combined with binding and dissociation assays.Zinc transporter type 8 autoantibodies (ZnT8A): prevalence and phenotypic associations in latent autoimmune diabetes patients and patients with adult onset type 1 diabetesAssociation Between SLC30A8 rs13266634 Polymorphism and Risk of T2DM and IGR in Chinese Population: A Systematic Review and Meta-Analysis
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P2860
Down-regulation of ZnT8 expression in INS-1 rat pancreatic beta cells reduces insulin content and glucose-inducible insulin secretion
description
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique PLoS ONE
@fr
artículu científicu espublizáu en 2009
@ast
im Mai 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/05/25)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/05/25)
@nl
наукова стаття, опублікована в травні 2009
@uk
name
Down-regulation of ZnT8 expres ...... se-inducible insulin secretion
@ast
Down-regulation of ZnT8 expres ...... se-inducible insulin secretion
@en
Down-regulation of ZnT8 expres ...... se-inducible insulin secretion
@nl
type
label
Down-regulation of ZnT8 expres ...... se-inducible insulin secretion
@ast
Down-regulation of ZnT8 expres ...... se-inducible insulin secretion
@en
Down-regulation of ZnT8 expres ...... se-inducible insulin secretion
@nl
prefLabel
Down-regulation of ZnT8 expres ...... se-inducible insulin secretion
@ast
Down-regulation of ZnT8 expres ...... se-inducible insulin secretion
@en
Down-regulation of ZnT8 expres ...... se-inducible insulin secretion
@nl
P2093
P2860
P1433
P1476
Down-regulation of ZnT8 expres ...... se-inducible insulin secretion
@en
P2093
Charles K. Meshul
David M. Cohen
Emily B. Pratt
Lisa B. Dirling
Show-Ling Shyng
P2860
P356
10.1371/JOURNAL.PONE.0005679
P407
P577
2009-05-25T00:00:00Z