Acute cytokine-mediated downregulation of the zinc transporter ZnT8 alters pancreatic beta-cell function. - Wikidata - awgldk - TriplyDB

Acute cytokine-mediated downregulation of the zinc transporter ZnT8 alters pancreatic beta-cell function.

Acute cytokine-mediated downregulation of the zinc transporter ZnT8 alters pancreatic beta-cell function.

http://www.wikidata.org/entity/Q30500111

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Current and Future Clinical Applications of Zinc Transporter-8 in Type 1 Diabetes Mellitus Zinc and zinc transporter regulation in pancreatic islets and the potential role of zinc in islet transplantation Accumulation of cadmium in insulin-producing β cells IL-1β at the crossroad between rheumatoid arthritis and type 2 diabetes: may we kill two birds with one stone?Zinc transporters and their role in the pancreatic β-cell.Exploring the Association Between Demographics, SLC30A8 Genotype, and Human Islet Content of Zinc, Cadmium, Copper, Iron, Manganese and Nickel Hypoxia lowers SLC30A8/ZnT8 expression and free cytosolic Zn2+ in pancreatic beta cells Islet autoantigens: structure, function, localization, and regulation.Imaging trace element distributions in single organelles and subcellular features The genetics of type 2 diabetes: what have we learned from GWAS?Zinc and insulin in pancreatic beta-cells.Macrophages and islet inflammation in type 2 diabetes.The plasma membrane metal-ion transporter ZIP14 contributes to nontransferrin-bound iron uptake by human β-cells.Inhibitory effect of zinc on glucose-stimulated zinc/insulin secretion in an insulin-secreting β-cell line.Rising intracellular zinc by membrane depolarization and glucose in insulin-secreting clonal HIT-T15 beta cells.Tumor necrosis factor α-induced protein-3 protects zinc transporter 8 against proinflammatory cytokine-induced downregulation.Reduction in Tcf7l2 expression decreases diabetic susceptibility in mice.Coupling of Insulin Secretion and Display of a Granule-resident Zinc Transporter ZnT8 on the Surface of Pancreatic Beta Cells.Implications of impaired zinc homeostasis in diabetic cardiomyopathy and nephropathy.Zinc transporter 8 autoantibody (ZnT8A) could help differentiate latent autoimmune diabetes in adults (LADA) from phenotypic type 2 diabetes mellitus.

P2860

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P2860

Acute cytokine-mediated downregulation of the zinc transporter ZnT8 alters pancreatic beta-cell function.

http://www.wikidata.org/entity/Q30500111

description

2010 nî lūn-bûn

@nan

2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Acute cytokine-mediated downre ...... pancreatic beta-cell function.

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Acute cytokine-mediated downre ...... pancreatic beta-cell function.

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type

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Acute cytokine-mediated downre ...... pancreatic beta-cell function.

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Acute cytokine-mediated downre ...... pancreatic beta-cell function.

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prefLabel

Acute cytokine-mediated downre ...... pancreatic beta-cell function.

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Acute cytokine-mediated downre ...... pancreatic beta-cell function.

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Journal of Endocrinology

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Acute cytokine-mediated downre ...... pancreatic beta-cell function.

@en

P2093

Dixon B Kaufman

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Liana K Billings

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Malek El Muayed

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Marsha V Newman

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Meera R Raja

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Paul J Park

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Thomas V O'Halloran

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William L Lowe

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Xiaomin Zhang

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P2860

In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

ZnT-8, a pancreatic beta-cell-specific zinc transporter

A genome-wide association study identifies novel risk loci for type 2 diabetes

Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion

The acrodermatitis enteropathica gene ZIP4 encodes a tissue-specific, zinc-regulated zinc transporter in mice

Down-regulation of ZnT8 expression in INS-1 rat pancreatic beta cells reduces insulin content and glucose-inducible insulin secretion

Zinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis?

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159-169

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scholarly article

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10.1677/JOE-09-0420

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2

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206

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2010-05-27T00:00:00Z

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20508080

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