Regulation of the epithelial sodium channel by N4WBP5A, a novel Nedd4/Nedd4-2-interacting protein
about
Cloning and characterization of N4WBP5A, an inducible, cyclosporine-sensitive, Nedd4-binding protein in human T lymphocytesThe ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channelsRespiratory distress and perinatal lethality in Nedd4-2-deficient miceIdentification of human gene products containing Pro-Pro-x-Tyr (PY) motifs that enhance glutathione and endocytotic marker uptake in yeastControl of the activity of WW-HECT domain E3 ubiquitin ligases by NDFIP proteinsNedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functionsSCAMP3 negatively regulates epidermal growth factor receptor degradation and promotes receptor recycling.MiR-23a/-24-induced gene silencing results in mesothelial cell integration of pancreatic cancerSpecificity and Autoregulation of Notch Binding by Tandem WW Domains in Suppressor of DeltexEar1p and Ssh4p are new adaptors of the ubiquitin ligase Rsp5p for cargo ubiquitylation and sorting at multivesicular bodiesRegulation of amino acid transporter ATA2 by ubiquitin ligase Nedd4-2Stimulation of the epithelial sodium channel (ENaC) by cAMP involves putative ERK phosphorylation sites in the C termini of the channel's beta- and gamma-subunitPOSH stimulates the ubiquitination and the clathrin-independent endocytosis of ROMK1 channels.Herpes simplex virus type 2 tegument protein UL56 relocalizes ubiquitin ligase Nedd4 and has a role in transport and/or release of virions.Pharmacogenomics of diuretic drugs: data on rare monogenic disorders and on polymorphisms and requirements for further research.Nedd4-2 functionally interacts with ClC-5: involvement in constitutive albumin endocytosis in proximal tubule cells.Protein kinase C-dependent ubiquitination and clathrin-mediated endocytosis of the cationic amino acid transporter CAT-1.Drosophila Ndfip is a novel regulator of Notch signaling.Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1.Unexpected diversity in Shisa-like proteins suggests the importance of their roles as transmembrane adaptors.Feedback inhibition of ENaC: acute and chronic mechanismsParticipation of the ubiquitin-conjugating enzyme UBE2E3 in Nedd4-2-dependent regulation of the epithelial Na+ channel.Ndfip2 is a potential regulator of the iron transporter DMT1 in the liverNdfip-mediated degradation of Jak1 tunes cytokine signalling to limit expansion of CD4+ effector T cellsUbiquitylation of Fe65 adaptor protein by neuronal precursor cell expressed developmentally down regulated 4-2 (Nedd4-2) via the WW domain interaction with Fe65.The Nedd4-2/Ndfip1 axis is a negative regulator of IgE-mediated mast cell activation.The delta-subunit of the epithelial sodium channel (ENaC) enhances channel activity and alters proteolytic ENaC activation.Deletion of Nedd4-2 results in progressive kidney disease in mice.Ubiquitination and the Regulation of Membrane Proteins.Ubiquitin-specific Protease 36 (USP36) Controls Neuronal Precursor Cell-expressed Developmentally Down-regulated 4-2 (Nedd4-2) Actions over the Neurotrophin Receptor TrkA and Potassium Voltage-gated Channels 7.2/3 (Kv7.2/3).NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology.Down-regulation of active ACK1 is mediated by association with the E3 ubiquitin ligase Nedd4-2.Protein kinase C (PKC)-promoted endocytosis of glutamate transporter GLT-1 requires ubiquitin ligase Nedd4-2-dependent ubiquitination but not phosphorylation.NDFIP allows NEDD4/NEDD4L-induced AQP2 ubiquitination and degradation.A mutation of the epithelial sodium channel associated with atypical cystic fibrosis increases channel open probability and reduces Na+ self inhibition.The gamma-subunit of ENaC is more important for channel surface expression than the beta-subunit.Cleavage in the {gamma}-subunit of the epithelial sodium channel (ENaC) plays an important role in the proteolytic activation of near-silent channels.Open probability of the epithelial sodium channel is regulated by intracellular sodium.
P2860
Q24304246-1CF6C4BA-BB84-4CC5-B21D-F27368A06889Q24328849-07F9FDB9-C225-4B25-A8F3-E9769B3DE84EQ24629880-8B8C0A10-E59E-4FC3-9B0C-CF15B78BA82DQ24632870-CD79DE35-AEC1-449D-B6CD-223273772323Q24645749-F6469D99-923E-44AE-A19A-2B7225ADC091Q24651528-DE041860-0926-4F72-8687-6D5BDB3A3E58Q24657896-6DB06701-3A01-4F4A-ACA9-E6710FC66F4CQ27332271-C5904A06-7241-4DC5-A05F-60F838AA927FQ27646888-55F739CC-52C0-4C7D-87BB-BDBECAC355A9Q27934201-024D8DE9-1F3E-48FE-8870-DAAADD3271A3Q28511126-920E6740-C340-420F-BF2E-C020E1C56B46Q28577168-A50EC823-4943-4795-B1F6-55AB10AE8866Q30157156-0D360F39-8FA4-4F03-92C6-DA586D5F7D1AQ30491300-EE6C989A-6EFE-46BB-9F6C-4947CA9D8178Q30883430-417028FB-32F9-4B53-91F8-C798EF5C14F3Q34359643-274351E0-FA90-40CC-A31F-016D3F3AA6BFQ34624572-93AA83FB-3974-4517-B6FB-86EC6F174FD1Q35092747-E62B2325-6C58-4CD2-AA2E-346F040415FDQ35623029-9999129F-D2FF-452C-AA2C-0ABACC47E90BQ35808585-C3A61743-B1D3-410C-8428-4870624CF831Q36125106-74C87E86-29D0-47E9-90AF-306A3C64959CQ36571577-ECC904DC-18A3-4DF9-9ABB-E3E242DF0563Q36769074-D12AA32A-921B-4E0D-BE9D-707268C8B337Q36815065-3B52F3B5-2F80-4949-ACB5-288C685780EFQ37337899-970F64FE-06DF-4138-B354-01DDBFA4957EQ37393354-134E07B9-BF32-4C84-874E-9CBDD2499AFDQ37431223-6292F1D6-6614-47A4-8164-011090073171Q38598033-ED9AF299-63EA-4E80-99FB-A166ABDB3254Q39033646-718E46F9-504D-4B7D-9894-B3CA0EAB0DF8Q41002813-25AA2F29-3129-4017-BC1A-3F04DE37180DQ41353750-1EBEBFD2-C774-4D68-AE63-ED64B1EF2763Q42100274-DAFB8FA3-2C3C-4EF3-AEE4-71B8A3EBA1A4Q42183018-54B325DC-4576-4211-8353-97722E7657CBQ42361463-DFBAB784-84A0-4B7B-970F-648C6B6703DFQ42651187-5EF8FF5E-6CB1-4395-AAD2-0C2EF7F2C2C9Q44279076-04E0E9E1-A32D-462C-B1FC-DCCEE2670DF7Q46453472-66BF0E0B-88F5-4DCF-AE94-AAA1F8E793CCQ50649426-D21382DB-0EAE-4B3D-AA82-E7F3CEDCE665
P2860
Regulation of the epithelial sodium channel by N4WBP5A, a novel Nedd4/Nedd4-2-interacting protein
description
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2002
@ast
im August 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/08/16)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/08/16)
@nl
наукова стаття, опублікована в серпні 2002
@uk
name
Regulation of the epithelial s ...... d4/Nedd4-2-interacting protein
@ast
Regulation of the epithelial s ...... d4/Nedd4-2-interacting protein
@en
Regulation of the epithelial s ...... d4/Nedd4-2-interacting protein
@nl
type
label
Regulation of the epithelial s ...... d4/Nedd4-2-interacting protein
@ast
Regulation of the epithelial s ...... d4/Nedd4-2-interacting protein
@en
Regulation of the epithelial s ...... d4/Nedd4-2-interacting protein
@nl
prefLabel
Regulation of the epithelial s ...... d4/Nedd4-2-interacting protein
@ast
Regulation of the epithelial s ...... d4/Nedd4-2-interacting protein
@en
Regulation of the epithelial s ...... d4/Nedd4-2-interacting protein
@nl
P2093
P2860
P3181
P356
P1476
Regulation of the epithelial s ...... d4/Nedd4-2-interacting protein
@en
P2093
Andrew B. Fotia
Angelos-Aristeidis Konstas
Christoph Korbmacher
Daniela Riccardi
David I. Cook
Linda M. Shearwin-Whyatt
P2860
P304
29406–29416
P3181
P356
10.1074/JBC.M203018200
P407
P577
2002-08-16T00:00:00Z