Regulation of carbohydrate metabolism by the farnesoid X receptor
about
Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta.Role of bile acids in the regulation of the metabolic pathwaysOrphan nuclear receptors and the regulation of nutrient metabolism: understanding obesityBile acid metabolism and signalingBile acid sequestration reduces plasma glucose levels in db/db mice by increasing its metabolic clearance rateThe antiparasitic drug ivermectin is a novel FXR ligand that regulates metabolismNuclear Receptors as Therapeutic Targets in Liver Disease: Are We There Yet?Bile Acid Nuclear Receptor Farnesoid X Receptor: Therapeutic Target for Nonalcoholic Fatty Liver DiseaseBile acid nuclear receptor FXR and digestive system diseasesDiacylglycerol kinase θ couples farnesoid X receptor-dependent bile acid signalling to Akt activation and glucose homoeostasis in hepatocytesThe nuclear receptor FXR is expressed in pancreatic beta-cells and protects human islets from lipotoxicityBile acid signaling in metabolic disease and drug therapyTranscriptional regulation of steroidogenic genes: STARD1, CYP11A1 and HSD3BFarnesoid X receptor: a master regulator of hepatic triglyceride and glucose homeostasisNutritional lipidomics: molecular metabolism, analytics, and diagnosticsFarnesoid X receptor agonist reduces serum asymmetric dimethylarginine levels through hepatic dimethylarginine dimethylaminohydrolase-1 gene regulationThe farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in miceFarnesoid X receptor is essential for normal glucose homeostasisStructural overview of the nuclear receptor superfamily: insights into physiology and therapeutics.Exposure to the synthetic FXR agonist GW4064 causes alterations in gene expression and sublethal hepatotoxicity in eleutheroembryo medaka (Oryzias latipes)Systemic gut microbial modulation of bile acid metabolism in host tissue compartments.Metabolomics approaches for characterizing metabolic interactions between host and its commensal microbes.The farnesoid X receptor modulates renal lipid metabolism and diet-induced renal inflammation, fibrosis, and proteinuria.Minireview: Nuclear receptor-controlled steroid hormone synthesis and metabolismCoordinated Actions of FXR and LXR in Metabolism: From Pathogenesis to Pharmacological Targets for Type 2 DiabetesBile acid receptor agonist GW4064 regulates PPARγ coactivator-1α expression through estrogen receptor-related receptor αActivation of Sirt1/FXR Signaling Pathway Attenuates Triptolide-Induced Hepatotoxicity in Rats.Bile acids regulate hepatic gluconeogenic genes and farnesoid X receptor via G(alpha)i-protein-coupled receptors and the AKT pathway.Retinoic acid represses CYP7A1 expression in human hepatocytes and HepG2 cells by FXR/RXR-dependent and independent mechanisms.Bile acid metabolites in serum: intraindividual variation and associations with coronary heart disease, metabolic syndrome and diabetes mellitusActivation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice.A comparative study of genome-wide transcriptional profiles of primary hepatocytes in collagen sandwich and monolayer cultures.FXR agonist GW4064 alleviates endotoxin-induced hepatic inflammation by repressing macrophage activation.Effect of chenodeoxycholic acid on fibrosis, inflammation and oxidative stress in kidney in high-fructose-fed Wistar rats.Endocrine functions of bile acids.Deciphering the nuclear bile acid receptor FXR paradigm.Role of bile acid sequestrants in the treatment of type 2 diabetesInsulin regulation of cholesterol 7alpha-hydroxylase expression in human hepatocytes: roles of forkhead box O1 and sterol regulatory element-binding protein 1c.Farnesoid X receptor deficiency improves glucose homeostasis in mouse models of obesity.Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure.
P2860
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P2860
Regulation of carbohydrate metabolism by the farnesoid X receptor
description
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im März 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/03/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/03/01)
@nl
наукова стаття, опублікована в березні 2005
@uk
مقالة علمية (نشرت في مارس 2005)
@ar
name
Regulation of carbohydrate metabolism by the farnesoid X receptor
@ast
Regulation of carbohydrate metabolism by the farnesoid X receptor
@en
Regulation of carbohydrate metabolism by the farnesoid X receptor
@nl
type
label
Regulation of carbohydrate metabolism by the farnesoid X receptor
@ast
Regulation of carbohydrate metabolism by the farnesoid X receptor
@en
Regulation of carbohydrate metabolism by the farnesoid X receptor
@nl
prefLabel
Regulation of carbohydrate metabolism by the farnesoid X receptor
@ast
Regulation of carbohydrate metabolism by the farnesoid X receptor
@en
Regulation of carbohydrate metabolism by the farnesoid X receptor
@nl
P2093
P3181
P356
P1433
P1476
Regulation of carbohydrate metabolism by the farnesoid X receptor
@en
P2093
James Ficorilli
Keith R Stayrook
Kelli S Bramlett
Laura F Michael
Michael E Christe
Rajesh S Savkur
P304
P3181
P356
10.1210/EN.2004-0965
P407
P50
P577
2004-11-24T00:00:00Z