Modulation of adrenal catecholamine secretion by in vivo gene transfer and manipulation of G protein-coupled receptor kinase-2 activity
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Adrenal G protein-coupled receptor kinase-2 in regulation of sympathetic nervous system activity in heart failureMolecular Mechanism for Inhibition of G Protein-Coupled Receptor Kinase 2 by a Selective RNA AptamerAn adrenal beta-arrestin 1-mediated signaling pathway underlies angiotensin II-induced aldosterone production in vitro and in vivoThe expanding GRK interactome: Implications in cardiovascular disease and potential for therapeutic development.Reduction of sympathetic activity via adrenal-targeted GRK2 gene deletion attenuates heart failure progression and improves cardiac function after myocardial infarctionImpaired desensitization of a human polymorphic α2B-adrenergic receptor variant enhances its sympatho-inhibitory activity in chromaffin cells.Adrenal gland infection by serotype 5 adenovirus requires coagulation factors.Adrenal beta-arrestin 1 inhibition in vivo attenuates post-myocardial infarction progression to heart failure and adverse remodeling via reduction of circulating aldosterone levels.Regulation of calcium channels and exocytosis in mouse adrenal chromaffin cells by prostaglandin EP3 receptorsG protein coupled receptor kinases as therapeutic targets in cardiovascular disease.GRK2 and β-arrestins in cardiovascular disease: Something old, something new.The evolving impact of g protein-coupled receptor kinases in cardiac health and diseaseMyocardial β(2) -adrenoceptor gene delivery promotes coordinated cardiac adaptive remodelling and angiogenesis in heart failure.Blockade of β-adrenoceptors restores the GRK2-mediated adrenal α(2) -adrenoceptor-catecholamine production axis in heart failureMyocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases.Structure-activity relationship study of angiotensin II analogs in terms of β-arrestin-dependent signaling to aldosterone production.Impact of diabetes on cardiac sympathetic innervation in patients with heart failure: a 123I meta-iodobenzylguanidine (123I MIBG) scintigraphic studyAdrenergic nervous system in heart failure: pathophysiology and therapy.Neuro-hormonal effects of physical activity in the elderly.Negative impact of β-arrestin-1 on post-myocardial infarction heart failure via cardiac and adrenal-dependent neurohormonal mechanisms.GRK2 as a novel gene therapy target in heart failure.G protein-coupled receptor kinases in normal and failing myocardium.Are the pharmacology and physiology of α₂ adrenoceptors determined by α₂-heteroreceptors and autoreceptors respectively?Targeting GRK2 by gene therapy for heart failure: benefits above β-blockade.Molecular aspects of the cardioprotective effect of exercise in the elderly.Physiology and pharmacology of the cardiovascular adrenergic system.Adrenal adrenoceptors in heart failure.Tailoring therapy for heart failure: the pharmacogenomics of adrenergic receptor signaling.Targeting GPCR-Gβγ-GRK2 signaling as a novel strategy for treating cardiorenal pathologies.Angiotensin receptor blocker drugs and inhibition of adrenal beta-arrestin-1-dependent aldosterone production: Implications for heart failure therapy.Alpha2-adrenoceptors in adrenomedullary chromaffin cells: functional role and pathophysiological implications.Adrenal GRK2 lowering is an underlying mechanism for the beneficial sympathetic effects of exercise training in heart failure.GRK2 as a therapeutic target for heart failure.β Adrenergic Receptor Kinase C-Terminal Peptide Gene-Therapy Improves β2-Adrenergic Receptor-Dependent Neoangiogenesis after Hindlimb Ischemia.Activation of lymphocyte autophagy/apoptosis reflects haemodynamic inefficiency and functional aerobic impairment in patients with heart failure.Suppressed G-protein-coupled receptor kinase 2 activity protects female diabetic-mouse aorta against endothelial dysfunction.
P2860
Q26785936-86993694-4E12-45B2-A39E-D9124639E2B3Q27681349-E9B8747C-2CF9-4EEF-B062-1786285856DFQ28578913-EC25FAA2-D032-484B-AAF1-9C52F2414EFBQ30250314-50E014D2-37C2-4F29-A658-D06281F80146Q33855337-2A30A7C4-7B8F-4F03-8178-1898E7EB863BQ34586312-FCE0412C-1DAE-4ACB-9964-CFB3BB211EAAQ34701038-4255FF49-0D9C-441D-8E14-8CC61F0B4582Q34925428-7EB1499B-817E-4C62-9C51-883B0AA456F5Q35008898-819DC985-2320-47E6-8DF5-BD20D20D420CQ35135090-4E367BC2-F182-4B9C-B913-F43DFE9FF4B5Q35660111-90E8E3CA-F028-4732-B186-E2A5E46C2407Q36000382-2AC2B9C9-2BE7-4E7A-8ED7-6CF0549A0F19Q36252791-AF897AA8-3E4F-4F83-A04C-C0725181178DQ36252811-805DC7AE-8851-4C52-BDFA-CFA4192BCAA3Q36651023-BB6B3706-21AB-4CD1-A01F-E5C3DF1C20D8Q36719641-AC8402DF-F09F-428F-A759-1D0A7870350BQ37022630-96889D28-A186-43F2-BC63-A122FB7F7727Q37349756-29BCF4C7-CA6F-45FC-B119-2908330D7B8EQ37404953-41262BC2-6E1C-4524-8F9A-908FE654DA7DQ37470858-162546FE-10E1-4299-A289-3A288A29FA9CQ37783642-78987641-3139-4542-9A72-79A21FF1AAE9Q37881660-4324A289-407C-4DE0-97AF-28E0653E94A9Q37887038-0AA70585-0D54-4D5E-AA65-2151DB69F127Q37984182-BFB80C4B-97A1-4263-BBB3-CDD6815D3966Q38129354-426F7E17-FFDF-4BC4-BD77-BBB0FD7161CBQ38136643-A91ADA24-3C57-4632-9775-26BA144A9BA1Q38234911-7B593E3A-4A6E-4864-81F1-F474034F8DACQ38256143-5E8481DE-89DE-4B79-83BF-2DF7D1FC483EQ39107039-817BB876-E6C7-4534-A80A-28354A500446Q42371966-DC9D1BB3-8881-41E5-9109-D79A43714848Q43061548-3BD3A746-A291-4EAF-974B-B193543DD951Q43122865-B2F4D2B7-4D95-4377-95DC-A5A4FB320773Q45874891-BCD0CD0E-0DA9-4D9B-A775-86C0BE52EEF5Q45880995-5B917E73-F453-4EF1-A1D3-4E65AE02449BQ48074906-FA2C19BC-446A-4F61-93CF-9C56C341E87EQ51315493-4193199A-8A24-4143-BF07-5B58FFFD8EA2
P2860
Modulation of adrenal catecholamine secretion by in vivo gene transfer and manipulation of G protein-coupled receptor kinase-2 activity
description
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
scientific journal article
@en
vedecký článok (publikovaný 2008/02/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/02/01)
@nl
наукова стаття, опублікована в лютому 2008
@uk
مقالة علمية (نشرت في فبراير 2008)
@ar
name
Modulation of adrenal catechol ...... led receptor kinase-2 activity
@ast
Modulation of adrenal catechol ...... led receptor kinase-2 activity
@en
Modulation of adrenal catechol ...... led receptor kinase-2 activity
@nl
type
label
Modulation of adrenal catechol ...... led receptor kinase-2 activity
@ast
Modulation of adrenal catechol ...... led receptor kinase-2 activity
@en
Modulation of adrenal catechol ...... led receptor kinase-2 activity
@nl
prefLabel
Modulation of adrenal catechol ...... led receptor kinase-2 activity
@ast
Modulation of adrenal catechol ...... led receptor kinase-2 activity
@en
Modulation of adrenal catechol ...... led receptor kinase-2 activity
@nl
P50
P356
P1433
P1476
Modulation of adrenal catechol ...... led receptor kinase-2 activity
@en
P2093
Stephen Soltys
Walter J. Koch
P304
P356
10.1038/SJ.MT.6300371
P577
2008-02-01T00:00:00Z