Promotion of non-rapid eye movement sleep and activation of reticular thalamic neurons by a novel MT2 melatonin receptor ligand
about
MT1 and MT2 Melatonin Receptors: A Therapeutic PerspectiveSustaining sleep spindles through enhanced SK2-channel activity consolidates sleep and elevates arousal threshold.Understanding melatonin receptor pharmacology: latest insights from mouse models, and their relevance to human disease.Piromelatine exerts antinociceptive effect via melatonin, opioid, and 5HT1A receptors and hypnotic effect via melatonin receptors in a mouse model of neuropathic pain.Melatonergic drugs in development.Therapeutic uses of melatonin and melatonin derivatives: a patent review (2012 - 2014).The MT2 receptor stimulates axonogenesis and enhances synaptic transmission by activating Akt signaling.Melatonin in aging and disease -multiple consequences of reduced secretion, options and limits of treatment.N-acetylserotonin: neuroprotection, neurogenesis, and the sleepy brainGenetic deletion of the MT1 or MT2 melatonin receptors abrogates methamphetamine-induced reward in C3H/HeN mice.Therapeutic applications of melatonin.The melatonergic system in mood and anxiety disorders and the role of agomelatine: implications for clinical practice.Unveiling the role of melatonin MT2 receptors in sleep, anxiety and other neuropsychiatric diseases: a novel target in psychopharmacology.Homology models of melatonin receptors: challenges and recent advances.Sites of action of sleep and wake drugs: insights from model organisms.The thalamic reticular nucleus: a functional hub for thalamocortical network dysfunction in schizophrenia and a target for drug discovery.Brain injury results in lower levels of melatonin receptors subtypes MT1 and MT2.Update on melatonin receptors: IUPHAR Review 20.A review of sleep disorders and melatonin.Melatonin receptors: distribution in mammalian brain and their respective putative functions.Melatonin receptor deficiency decreases and temporally shifts ecto-5'-nucleotidase mRNA levels in mouse prosencephalon.Anatomical and cellular localization of melatonin MT1 and MT2 receptors in the adult rat brain.Elevated Neurosteroids in the Lateral Thalamus Relieve Neuropathic Pain in Rats with Spared Nerve Injury.MT1-selective melatonin receptor ligands: synthesis, pharmacological evaluation, and molecular dynamics investigation of N-{[(3-O-substituted)anilino]alkyl}amides.Melatonin signaling controls circadian swimming behavior in marine zooplankton.Food-Induced Reinforcement is Abrogated by the Genetic Deletion of the MT1 or MT2 Melatonin Receptor in C3H/HeN Mice.Epigenetic regulation of melatonin receptors in neuropsychiatric disorders.Pharmacological characterization of M-II, the major human metabolite of ramelteon.Specific melatonin receptor promotes a deeper sleep.Melatonin transport into mitochondria.Challenges of the pharmacological management of benzodiazepine withdrawal, dependence, and discontinuation.
P2860
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P2860
Promotion of non-rapid eye movement sleep and activation of reticular thalamic neurons by a novel MT2 melatonin receptor ligand
description
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
@ast
im Dezember 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/12/14)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/12/14)
@nl
наукова стаття, опублікована в грудні 2011
@uk
مقالة علمية (نشرت في 14-12-2011)
@ar
name
Promotion of non-rapid eye mov ...... MT2 melatonin receptor ligand
@ast
Promotion of non-rapid eye mov ...... MT2 melatonin receptor ligand
@en
Promotion of non-rapid eye mov ...... MT2 melatonin receptor ligand
@nl
type
label
Promotion of non-rapid eye mov ...... MT2 melatonin receptor ligand
@ast
Promotion of non-rapid eye mov ...... MT2 melatonin receptor ligand
@en
Promotion of non-rapid eye mov ...... MT2 melatonin receptor ligand
@nl
prefLabel
Promotion of non-rapid eye mov ...... MT2 melatonin receptor ligand
@ast
Promotion of non-rapid eye mov ...... MT2 melatonin receptor ligand
@en
Promotion of non-rapid eye mov ...... MT2 melatonin receptor ligand
@nl
P2093
P50
P1476
Promotion of non-rapid eye mov ...... MT2 melatonin receptor ligand
@en
P2093
Debora Angeloni
Francis Rodriguez Bambico
Franco Fraschini
Giorgio Tarzia
Laurent Descarries
Rafael Ochoa-Sanchez
P304
18439-18452
P356
10.1523/JNEUROSCI.2676-11.2011
P407
P50
P577
2011-12-01T00:00:00Z