Myc suppresses induction of the growth arrest genes gadd34, gadd45, and gadd153 by DNA-damaging agents
about
GADD45 proteins: central players in tumorigenesisAdenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1Gadd45 proteins as critical signal transducers linking NF-kappaB to MAPK cascadesHes-1 SUMOylation by protein inhibitor of activated STAT1 enhances the suppressing effect of Hes-1 on GADD45α expression to increase cell survivalTFIIH operates through an expanded proximal promoter to fine-tune c-myc expression.Myc induces the nucleolin and BN51 genes: possible implications in ribosome biogenesisMyc-mediated transformation: the repression connection.Myc interacts with Max and Miz1 to repress C/EBPdelta promoter activity and gene expression.Myc is an essential negative regulator of platelet-derived growth factor beta receptor expression.BRCA1 and cell signaling.ATF3 induction following DNA damage is regulated by distinct signaling pathways and over-expression of ATF3 protein suppresses cells growth.Gadd45 proteins: relevance to aging, longevity and age-related pathologies.MYC-regulated genes involved in liver cell dysplasia identified in a transgenic model of liver cancer.Genomic instability, centrosome amplification, cell cycle checkpoints and Gadd45a.Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3.Defective double-strand DNA break repair and chromosomal translocations by MYC overexpression.Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts.The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cellsSIRT1 activation enhances HDAC inhibition-mediated upregulation of GADD45G by repressing the binding of NF-κB/STAT3 complex to its promoter in malignant lymphoid cells.Apoptotic signaling by c-MYC.Posttranscriptional regulation of gene expression-adding another layer of complexity to the DNA damage response.Implications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part I: targeting p53, Mdm2, GADD153/CHOP, GRP78/BiP and heat shock proteins.Cross-talk between the circadian clock and the cell cycle in cancer.Elucidation of a novel phenformin derivative on glucose-deprived stress responses in HT-29 cells.The involvement of WT1 in the regulation of GADD45a in response to genotoxic stress.The novel function of OCT4B isoform-265 in genotoxic stress.Treatment of cholangiocarcinoma with oncolytic herpes simplex virus combined with external beam radiation therapy.Identification of Myc-mediated death response pathways by microarray analysis.c-Myc and Sp1 contribute to proviral latency by recruiting histone deacetylase 1 to the human immunodeficiency virus type 1 promoter.Oncogenomics of c-Myc transgenic mice reveal novel regulators of extracellular signaling, angiogenesis and invasion with clinical significance for human lung adenocarcinoma.Transforming ability of Gag-Myc fusion proteins correlates with Gag-Myc protein stability and transcriptional repression.
P2860
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P2860
Myc suppresses induction of the growth arrest genes gadd34, gadd45, and gadd153 by DNA-damaging agents
description
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
@ast
im Oktober 1998 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 1998/10/29)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/10/29)
@nl
наукова стаття, опублікована в жовтні 1998
@uk
مقالة علمية (نشرت في 29-10-1998)
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name
Myc suppresses induction of th ...... gadd153 by DNA-damaging agents
@ast
Myc suppresses induction of th ...... gadd153 by DNA-damaging agents
@en
Myc suppresses induction of th ...... gadd153 by DNA-damaging agents
@nl
type
label
Myc suppresses induction of th ...... gadd153 by DNA-damaging agents
@ast
Myc suppresses induction of th ...... gadd153 by DNA-damaging agents
@en
Myc suppresses induction of th ...... gadd153 by DNA-damaging agents
@nl
prefLabel
Myc suppresses induction of th ...... gadd153 by DNA-damaging agents
@ast
Myc suppresses induction of th ...... gadd153 by DNA-damaging agents
@en
Myc suppresses induction of th ...... gadd153 by DNA-damaging agents
@nl
P356
P1433
P1476
Myc suppresses induction of th ...... gadd153 by DNA-damaging agents
@en
P2093
P2888
P304
P356
10.1038/SJ.ONC.1202136
P407
P577
1998-10-01T00:00:00Z
P5875
P6179
1030868528