Autophosphorylation modulates the kinase activity and oncogenic potential of the Met receptor tyrosine kinase
about
Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transductionRegulation of the Met receptor-tyrosine kinase by the protein-tyrosine phosphatase 1B and T-cell phosphataseGrb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesisThe Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinaseThe MET axis as a therapeutic target.An overview of the c-MET signaling pathwayBiomarker development in MET-targeted therapyTargeting the epithelial to mesenchymal transition in glioblastoma: the emerging role of MET signalingActivation of the JNK pathway is essential for transformation by the Met oncogeneDirect interaction of focal adhesion kinase (FAK) with Met is required for FAK to promote hepatocyte growth factor-induced cell invasion.Analysis of progress and challenges for various patterns of c-MET-targeted molecular imaging: a systematic review.Valproic acid, targets papillary thyroid cancer through inhibition of c-Met signalling pathwayEnhanced transformation by a plasma membrane-associated met oncoprotein: activation of a phosphoinositide 3'-kinase-dependent autocrine loop involving hyaluronic acid and CD44.Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy.Involvement of an SHP-2-Rho small G protein pathway in hepatocyte growth factor/scatter factor-induced cell scattering.The role of the c-Met pathway in lung cancer and the potential for targeted therapy.Artificial human Met agonists based on macrocycle scaffoldsCD44 plays a functional role in Helicobacter pylori-induced epithelial cell proliferation.Expression of c-Met and heparan-sulfate proteoglycan forms of CD44 in colorectal cancerTargeting the HGF/c-MET pathway in hepatocellular carcinoma.Degradation of the Met tyrosine kinase receptor by the ubiquitin-proteasome pathwayActivating mutations for the met tyrosine kinase receptor in human cancer.MET as a possible target for non-small-cell lung cancer.Deleting the TGF-β receptor in proximal tubules impairs HGF signalingCurrent understanding of the molecular mechanisms of kidney cancer: a primer for urologists.MET as a target for treatment of chest tumorsBiochemical basis for the functional switch that regulates hepatocyte growth factor receptor tyrosine kinase activationMET pathway as a therapeutic target.Targeting MET kinase with the small-molecule inhibitor amuvatinib induces cytotoxicity in primary myeloma cells and cell lines.c-Met expression and activity in urogenital cancers - novel aspects of signal transduction and medical implications.Hepatocyte growth factor in lung repair and pulmonary fibrosis.Promise and challenges on the horizon of MET-targeted cancer therapeuticsSignaling by METMET Receptor ActivationBiological roles of hepatocyte growth factor-Met signaling from genetically modified animals.MET dimers autophosphorylateCellular signaling and gene expression profiles evoked by a bivalent macrocyclic peptide that serves as an artificial MET receptor agonist
P2860
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P2860
Autophosphorylation modulates the kinase activity and oncogenic potential of the Met receptor tyrosine kinase
description
1994 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1994
@ast
im Juli 1994 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1994/07/01)
@sk
vědecký článek publikovaný v roce 1994
@cs
wetenschappelijk artikel (gepubliceerd op 1994/07/01)
@nl
наукова стаття, опублікована в липні 1994
@uk
مقالة علمية (نشرت في يوليو 1994)
@ar
name
Autophosphorylation modulates ...... e Met receptor tyrosine kinase
@ast
Autophosphorylation modulates ...... e Met receptor tyrosine kinase
@en
Autophosphorylation modulates ...... e Met receptor tyrosine kinase
@nl
type
label
Autophosphorylation modulates ...... e Met receptor tyrosine kinase
@ast
Autophosphorylation modulates ...... e Met receptor tyrosine kinase
@en
Autophosphorylation modulates ...... e Met receptor tyrosine kinase
@nl
prefLabel
Autophosphorylation modulates ...... e Met receptor tyrosine kinase
@ast
Autophosphorylation modulates ...... e Met receptor tyrosine kinase
@en
Autophosphorylation modulates ...... e Met receptor tyrosine kinase
@nl
P3181
P1433
P1476
Autophosphorylation modulates ...... e Met receptor tyrosine kinase
@en
P2093
P304
P3181
P407
P577
1994-07-01T00:00:00Z