Direct interaction of focal adhesion kinase (FAK) with Met is required for FAK to promote hepatocyte growth factor-induced cell invasion. - Wikidata - awgldk - TriplyDB

Direct interaction of focal adhesion kinase (FAK) with Met is required for FAK to promote hepatocyte growth factor-induced cell invasion.

Direct interaction of focal adhesion kinase (FAK) with Met is required for FAK to promote hepatocyte growth factor-induced cell invasion.

http://www.wikidata.org/entity/Q30445760

about

MicroRNA-34a modulates c-Myc transcriptional complexes to suppress malignancy in human prostate cancer cells Phosphorylation of focal adhesion kinase on tyrosine 194 by Met leads to its activation through relief of autoinhibition Focal adhesion kinase: switching between GAPs and GEFs in the regulation of cell motility Structural basis for the autoinhibition of focal adhesion kinase FAK acts as a suppressor of RTK-MAP kinase signalling in Drosophila melanogaster epithelia and human cancer cells FAK dimerization controls its kinase-dependent functions at focal adhesions Phosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changes Mechanism of Focal Adhesion Kinase Mechanosensing Ligand-independent activation of c-Met by fibronectin and α(5)β(1)-integrin regulates ovarian cancer invasion and metastasis.Helicobacter pylori CagA induces AGS cell elongation through a cell retraction defect that is independent of Cdc42, Rac1, and Arp2/3.FAK phosphorylation at Tyr-925 regulates cross-talk between focal adhesion turnover and cell protrusion.Roles of focal adhesion kinase (FAK) in megakaryopoiesis and platelet function: studies using a megakaryocyte lineage specific FAK knockout.Inhibiting the interaction of cMET and IGF-1R with FAK effectively reduces growth of pancreatic cancer cells in vitro and in vivo Focal adhesion kinase: a prominent determinant in breast cancer initiation, progression and metastasis Mechanisms of the epithelial-mesenchymal transition by TGF-beta Tetraspan TM4SF5-dependent direct activation of FAK and metastatic potential of hepatocarcinoma cells HGF/c-met/Stat3 signaling during skin tumor cell invasion: indications for a positive feedback loop.C1GALT1 promotes invasive phenotypes of hepatocellular carcinoma cells by modulating integrin β1 glycosylation and activity Key roles for GRB2-associated-binding protein 1, phosphatidylinositol-3-kinase, cyclooxygenase 2, prostaglandin E2 and transforming growth factor alpha in linoleic acid-induced upregulation of lung and breast cancer cell growth.Mda-9/syntenin is expressed in uveal melanoma and correlates with metastatic progression Essential role for focal adhesion kinase in regulating stress hematopoiesis.Activation of endogenous FAK via expression of its amino terminal domain in Xenopus embryos FAK is required for c-Met/β-catenin-driven hepatocarcinogenesis.A PAK-activated linker for EGFR and FAK Allosteric regulation of focal adhesion kinase by PIP₂ and ATP.Inhibition of FAK and VEGFR-3 binding decreases tumorigenicity in neuroblastoma.New insights into FAK phosphorylation based on a FAT domain-defective mutation FAK is required for the assembly of podosome rosettes How focal adhesion kinase achieves regulation by linking ligand binding, localization and action Reorganization of the integrin alpha2 subunit controls cell adhesion and cancer cell invasion in prostate cancer Thyroid hormone-mediated regulation of lipocalin 2 through the Met/FAK pathway in liver cancer.Phospholipid binding to the FAK catalytic domain impacts function.A small-molecule inhibitor, 5'-O-tritylthymidine, targets FAK and Mdm-2 interaction, and blocks breast and colon tumorigenesis in vivo.Genome-wide analysis of Musashi-2 targets reveals novel functions in governing epithelial cell migration Disrupting the scaffold to improve focal adhesion kinase-targeted cancer therapeutics ERK1/2 activation in heart is controlled by melusin, focal adhesion kinase and the scaffold protein IQGAP1 Focal adhesion kinase versus p53: apoptosis or survival?FERM control of FAK function: implications for cancer therapy.Interplay between FAK, PKCδ, and p190RhoGAP in the regulation of endothelial barrier function.Focal adhesion kinase regulation of mechanotransduction and its impact on endothelial cell functions.

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P2860

Direct interaction of focal adhesion kinase (FAK) with Met is required for FAK to promote hepatocyte growth factor-induced cell invasion.

http://www.wikidata.org/entity/Q30445760

description

2006 nî lūn-bûn

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2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2006 թվականի հուլիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Direct interaction of focal ad ...... factor-induced cell invasion.

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Direct interaction of focal ad ...... factor-induced cell invasion.

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type

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Direct interaction of focal ad ...... factor-induced cell invasion.

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Direct interaction of focal ad ...... factor-induced cell invasion.

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Direct interaction of focal ad ...... factor-induced cell invasion.

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Direct interaction of focal ad ...... factor-induced cell invasion.

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Molecular and Cellular Biology

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Direct interaction of focal ad ...... factor-induced cell invasion.

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Hong-Chen Chen

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Shu-Yi Chen

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P2860

Regulation of the PH-domain-containing tyrosine kinase Etk by focal adhesion kinase through the FERM domain

Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product

Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain

Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions.

Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains.

Essential role of Gab1 for signaling by the c-Met receptor in vivo

Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain

Structure of the active N-terminal domain of Ezrin. Conformational and mobility changes identify keystone interactions

Three-dimensional structure of the complex between acyl-coenzyme A binding protein and palmitoyl-coenzyme A

The motogenic and mitogenic responses to HGF are amplified by the Shc adaptor protein

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5155-5167

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scholarly article

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10.1128/MCB.02186-05

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13

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26

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2006-07-01T00:00:00Z

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16782899

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1489146

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