Reconstitution of B cell antigen receptor-induced signaling events in a nonlymphoid cell line by expressing the Syk protein-tyrosine kinase
about
The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathwaysDifferential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinasesThe src homology domain 2-containing inositol phosphatase SHIP forms a ternary complex with Shc and Grb2 in antigen receptor-stimulated B lymphocytesShc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytesA critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophagesFunctional independence and interdependence of the Src homology domains of phospholipase C-gamma1 in B-cell receptor signal transduction.Critical Role for an acidic amino acid region in platelet signaling by the HemITAM (hemi-immunoreceptor tyrosine-based activation motif) containing receptor CLEC-2 (C-type lectin receptor-2).Hematopoietic cell-specific adapter proteins, SLP-76 and BLNK, effectively activate NF-AT as well as NF-kappaB by Syk and Tec PTKs in non-lymphoid cell lines.The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in macrophages and neutrophilsThe Gab1 docking protein links the b cell antigen receptor to the phosphatidylinositol 3-kinase/Akt signaling pathway and to the SHP2 tyrosine phosphatase.Regulation of phospholipase C-gamma2 and phosphoinositide 3-kinase pathways by adaptor proteins in B lymphocytes.Regulation of B-cell signal transduction by adaptor proteins.Selection of B lymphocytes in the periphery is determined by the functional capacity of the B cell antigen receptorFcgamma receptor-mediated phagocytosis in macrophages lacking the Src family tyrosine kinases Hck, Fgr, and Lyn.Enhancement of lymphocyte responsiveness by a gain-of-function mutation of ZAP-70.Regulation of T-cell antigen receptor signalling by Syk tyrosine protein kinaseThe molecular mechanism of B cell activation by toll-like receptor protein RP-105Role of Syk in B-cell development and antigen-receptor signalingGeneration of a novel system for studying spleen tyrosine kinase function in macrophages and B cells.Antibody cross-linking of the glycosylphosphatidylinositol-linked protein CD59 on hematopoietic cells induces signaling pathways resembling activation by complement.Volume expansion stimulates p72(syk) and p56(lyn) in skate erythrocytes.
P2860
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P248
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P2860
Reconstitution of B cell antigen receptor-induced signaling events in a nonlymphoid cell line by expressing the Syk protein-tyrosine kinase
description
1996 nî lūn-bûn
@nan
1996 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի մարտին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
name
Reconstitution of B cell antig ...... he Syk protein-tyrosine kinase
@ast
Reconstitution of B cell antig ...... he Syk protein-tyrosine kinase
@en
Reconstitution of B cell antig ...... he Syk protein-tyrosine kinase
@nl
type
label
Reconstitution of B cell antig ...... he Syk protein-tyrosine kinase
@ast
Reconstitution of B cell antig ...... he Syk protein-tyrosine kinase
@en
Reconstitution of B cell antig ...... he Syk protein-tyrosine kinase
@nl
prefLabel
Reconstitution of B cell antig ...... he Syk protein-tyrosine kinase
@ast
Reconstitution of B cell antig ...... he Syk protein-tyrosine kinase
@en
Reconstitution of B cell antig ...... he Syk protein-tyrosine kinase
@nl
P2093
P2860
P921
P356
P1476
Reconstitution of B cell antig ...... he Syk protein-tyrosine kinase
@en
P2093
A L DeFranco
J D Richards
L Matsuuchi
S L Hourihane
P2860
P304
P356
10.1074/JBC.271.11.6458
P407
P577
1996-03-01T00:00:00Z