Trafficking and surface expression of hyperpolarization-activated cyclic nucleotide-gated channels in hippocampal neurons
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Searching for new targets for treatment of pediatric epilepsyThe acid-sensitive, anesthetic-activated potassium leak channel, KCNK3, is regulated by 14-3-3β-dependent, protein kinase C (PKC)-mediated endocytic trafficking.Distinct regional and subcellular localization of the actin-binding protein filamin A in the mature rat brainNeuron-restrictive silencer factor-mediated hyperpolarization-activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsyElectrophysiological changes precede morphological changes to frontal cortical pyramidal neurons in the rTg4510 mouse model of progressive tauopathyDistinct perinatal features of the hyperpolarization-activated non-selective cation current I(h) in the rat cortical plate.Abnormal dendritic maturation of developing cortical neurons exposed to corticotropin releasing hormone (CRH): Insights into effects of prenatal adversity?NRSF-dependent epigenetic mechanisms contribute to programming of stress-sensitive neurons by neonatal experience, promoting resilienceRegulation of axonal HCN1 trafficking in perforant path involves expression of specific TRIP8b isoforms.Reelin signaling specifies the molecular identity of the pyramidal neuron distal dendritic compartment.HCN1 and HCN2 in Rat DRG neurons: levels in nociceptors and non-nociceptors, NT3-dependence and influence of CFA-induced skin inflammation on HCN2 and NT3 expressionHCN Channel Targets for Novel Antidepressant Treatment.A di-arginine ER retention signal regulates trafficking of HCN1 channels from the early secretory pathway to the plasma membrane.Trafficking and gating of hyperpolarization-activated cyclic nucleotide-gated channels are regulated by interaction with tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b) and cyclic AMP at distinct sites.Rapid loss of dendritic HCN channel expression in hippocampal pyramidal neurons following status epilepticusDecreased hyperpolarization-activated currents in layer 5 pyramidal neurons enhances excitability in focal cortical dysplasia.Tonic 5nM DA stabilizes neuronal output by enabling bidirectional activity-dependent regulation of the hyperpolarization activated current via PKA and calcineurin.Impairment of synaptic plasticity by the stress mediator CRH involves selective destruction of thin dendritic spines via RhoA signalingActivation of high and low affinity dopamine receptors generates a closed loop that maintains a conductance ratio and its activity correlate.Dopamine D4 receptor excitation of lateral habenula neurons via multiple cellular mechanisms.NMDA receptor activation and calpain contribute to disruption of dendritic spines by the stress neuropeptide CRH.Filamin A promotes dynamin-dependent internalization of hyperpolarization-activated cyclic nucleotide-gated type 1 (HCN1) channels and restricts Ih in hippocampal neurons.Towards an integrated view of HCN channel role in epilepsy.The intersection of amyloid β and tau in glutamatergic synaptic dysfunction and collapse in Alzheimer's disease.Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channels in EpilepsyEssential roles of AMPA receptor GluA1 phosphorylation and presynaptic HCN channels in fast-acting antidepressant responses of ketamine.Differential regulation of HCN channel isoform expression in thalamic neurons of epileptic and non-epileptic rat strains.Homeostatic regulation of h-conductance controls intrinsic excitability and stabilizes the threshold for synaptic modification in CA1 neurons.SUMOylation of the Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 2 Increases Surface Expression and the Maximal Conductance of the Hyperpolarization-Activated Current.Tonic nanomolar dopamine enables an activity-dependent phase recovery mechanism that persistently alters the maximal conductance of the hyperpolarization-activated current in a rhythmically active neuron.Not RESTing on Its Laurels: Timing and Mechanisms of HCN Channel Dysfunction in Epilepsy.HCN1 subunits contribute to the kinetics of I(h) in neonatal cortical plate neurons.Calcium permeable AMPA receptor-dependent long lasting plasticity of intrinsic excitability in fast spiking interneurons of the dentate gyrus decreases inhibition in the granule cell layer.HCN1 channels: a new therapeutic target for depressive disorders?Distal Dendritic Enrichment of HCN1 Channels in Hippocampal CA1 Is Promoted by Estrogen, but Does Not Require Reelin
P2860
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P2860
Trafficking and surface expression of hyperpolarization-activated cyclic nucleotide-gated channels in hippocampal neurons
description
2010 nî lūn-bûn
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2010 թուականի Մարտին հրատարակուած գիտական յօդուած
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2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Trafficking and surface expres ...... hannels in hippocampal neurons
@ast
Trafficking and surface expres ...... hannels in hippocampal neurons
@en
Trafficking and surface expres ...... hannels in hippocampal neurons
@nl
type
label
Trafficking and surface expres ...... hannels in hippocampal neurons
@ast
Trafficking and surface expres ...... hannels in hippocampal neurons
@en
Trafficking and surface expres ...... hannels in hippocampal neurons
@nl
prefLabel
Trafficking and surface expres ...... hannels in hippocampal neurons
@ast
Trafficking and surface expres ...... hannels in hippocampal neurons
@en
Trafficking and surface expres ...... hannels in hippocampal neurons
@nl
P2093
P2860
P356
P1476
Trafficking and surface expres ...... hannels in hippocampal neurons
@en
P2093
Dane M Chetkovich
Qinqin Zha
Rui-Lin Wu
Tallie Z Baram
Wytse J Wadman
P2860
P304
14724-14736
P356
10.1074/JBC.M109.070391
P407
P577
2010-03-09T00:00:00Z