The tumor suppressor gene LKB1 is associated with prognosis in human breast carcinoma
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SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasisHonokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesisUncoupling of the LKB1-AMPKalpha energy sensor pathway by growth factors and oncogenic BRAFAMPK activators suppress cervical cancer cell growth through inhibition of DVL3 mediated Wnt/β-catenin signaling activityThe induction of autophagy by mechanical stress.Integrin-binding protein nischarin interacts with tumor suppressor liver kinase B1 (LKB1) to regulate cell migration of breast epithelial cells.Downregulation of LKB1 promotes tumor progression and predicts unfavorable prognosis in patients with glioma.The transcriptional responsiveness of LKB1 to STAT-mediated signaling is differentially modulated by prolactin in human breast cancer cells.Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1.AMPK reverses the mesenchymal phenotype of cancer cells by targeting the Akt-MDM2-Foxo3a signaling axis.LKB1 is required for adiponectin-mediated modulation of AMPK-S6K axis and inhibition of migration and invasion of breast cancer cellsGermline variation in TP53 regulatory network genes associates with breast cancer survival and treatment outcome.Metastasis suppression by adiponectin: LKB1 rises up to the challenge.LKB1 is a central regulator of tumor initiation and pro-growth metabolism in ErbB2-mediated breast cancer.LKB1, the multitasking tumour suppressor kinaseLKB1 inhibits breast cancer partially through repressing the Hedgehog signaling pathway.Liver kinase B1 (LKB1) in the pathogenesis of epithelial cancersSmall molecule adenosine 5'-monophosphate activated protein kinase (AMPK) modulators and human diseasesTargeting energy metabolic and oncogenic signaling pathways in triple-negative breast cancer by a novel adenosine monophosphate-activated protein kinase (AMPK) activatorLoss of LKB1 disrupts breast epithelial cell polarity and promotes breast cancer metastasis and invasion.Metformin: multi-faceted protection against cancer.Tumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrityThe Prognostic Value of Decreased LKB1 in Solid Tumors: A Meta-AnalysisRegulation of triple-negative breast cancer cell metastasis by the tumor-suppressor liver kinase B1.AMPK Inhibits the Stimulatory Effects of TGF-β on Smad2/3 Activity, Cell Migration, and Epithelial-to-Mesenchymal Transition.Honokiol activates LKB1-miR-34a axis and antagonizes the oncogenic actions of leptin in breast cancer.Peutz-Jeghers Syndrome with multiple genital tract tumors and breast cancer: a case report with a review of literaturesClinical Relevance of Liver Kinase B1(LKB1) Protein and Gene Expression in Breast CancerLKB1/AMPK inhibits TGF-β1 production and the TGF-β signaling pathway in breast cancer cells.Cucurbitane Triterpenoid from Momordica charantia Induces Apoptosis and Autophagy in Breast Cancer Cells, in Part, through Peroxisome Proliferator-Activated Receptor γ Activation.Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ERalpha negative MDA-MB-435 breast cancer modelCell cycle arrest in Metformin treated breast cancer cells involves activation of AMPK, downregulation of cyclin D1, and requires p27Kip1 or p21Cip1.Roles of the WWOX in pathogenesis and endocrine therapy of breast cancer.Breaking the epithelial polarity barrier in cancer: the strange case of LKB1/PAR-4LKB1 catalytic activity contributes to estrogen receptor alpha signalingBenzyl Isothiocyanate potentiates p53 signaling and antitumor effects against breast cancer through activation of p53-LKB1 and p73-LKB1 axes.Polarity protein alterations in carcinoma: a focus on emerging roles for polarity regulators.The LKB1 complex-AMPK pathway: the tree that hides the forestCalcium-Oxidant Signaling Network Regulates AMP-activated Protein Kinase (AMPK) Activation upon Matrix Deprivation.LKB1 suppresses proliferation and invasion of prostate cancer through hedgehog signaling pathway.
P2860
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P2860
The tumor suppressor gene LKB1 is associated with prognosis in human breast carcinoma
description
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im Juli 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/07/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/07/01)
@nl
наукова стаття, опублікована в липні 2002
@uk
مقالة علمية (نشرت في يوليو 2002)
@ar
name
The tumor suppressor gene LKB1 is associated with prognosis in human breast carcinoma
@ast
The tumor suppressor gene LKB1 is associated with prognosis in human breast carcinoma
@en
The tumor suppressor gene LKB1 is associated with prognosis in human breast carcinoma
@nl
type
label
The tumor suppressor gene LKB1 is associated with prognosis in human breast carcinoma
@ast
The tumor suppressor gene LKB1 is associated with prognosis in human breast carcinoma
@en
The tumor suppressor gene LKB1 is associated with prognosis in human breast carcinoma
@nl
prefLabel
The tumor suppressor gene LKB1 is associated with prognosis in human breast carcinoma
@ast
The tumor suppressor gene LKB1 is associated with prognosis in human breast carcinoma
@en
The tumor suppressor gene LKB1 is associated with prognosis in human breast carcinoma
@nl
P2093
P3181
P1476
The tumor suppressor gene LKB1 is associated with prognosis in human breast carcinoma
@en
P2093
Xian-Feng Wen
Zhen-Zhou Shen
Zhi-Ming Shao
P304
P3181
P407
P577
2002-07-01T00:00:00Z