Endoplasmic reticulum stress and trophic factor withdrawal activate distinct signaling cascades that induce glycogen synthase kinase-3 beta and a caspase-9-dependent apoptosis in cerebellar granule neurons
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GSK-3 Inhibitors: Preclinical and Clinical Focus on CNSXenobiotic perturbation of ER stress and the unfolded protein responseGSK3beta in ethanol neurotoxicityThe role of GSK3beta in the development of the central nervous systemValproate attenuates accelerated atherosclerosis in hyperglycemic apoE-deficient mice: evidence in support of a role for endoplasmic reticulum stress and glycogen synthase kinase-3 in lesion development and hepatic steatosis.Involvement of 4E-BP1 in the protection induced by HDLs on pancreatic beta-cells.Identification of agents that promote endoplasmic reticulum stress using an assay that monitors luciferase secretion.Autophagy, and BiP level decrease are early key events in retrograde degeneration of motoneuronsEndoplasmic reticulum stress or mutation of an EF-hand Ca(2+)-binding domain directs the FKBP65 rotamase to an ERAD-based proteolysisTransgenic mouse and cell culture models demonstrate a lack of mechanistic connection between endoplasmic reticulum stress and tau dysfunction.HSP105 interacts with GRP78 and GSK3 and promotes ER stress-induced caspase-3 activationA Christianson syndrome-linked deletion mutation (∆(287)ES(288)) in SLC9A6 disrupts recycling endosomal function and elicits neurodegeneration and cell deathThe endoplasmic reticulum in apoptosis and autophagy: role of the BCL-2 protein family.Linking Alzheimer's disease to insulin resistance: the FoxO response to oxidative stress.Signaling pathways involved in endoplasmic reticulum stress-induced neuronal apoptosis.Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cells via stress-mediated pathways.Insulin-like growth factor 1 rescues R28 retinal neurons from apoptotic death through ERK-mediated BimEL phosphorylation independent of Akt.Endoplasmic reticulum stress inhibition protects steatotic and non-steatotic livers in partial hepatectomy under ischemia-reperfusion.Glycogen synthase kinase-3 regulates endoplasmic reticulum (ER) stress-induced CHOP expression in neuronal cells.Liraglutide restores chronic ER stress, autophagy impairments and apoptotic signalling in SH-SY5Y cells.SOX7 interferes with β-catenin activity to promote neuronal apoptosis.Endoplasmic reticulum stress-induced apoptosis in the penumbra aggravates secondary damage in rats with traumatic brain injury.Unfolded protein response is activated in the ipsilateral thalamus following focal cerebral infarction in hypertensive rats.Insights on the involvement of (-)-epigallocatechin gallate in ER stress-mediated apoptosis in age-related macular degeneration.
P2860
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P2860
Endoplasmic reticulum stress and trophic factor withdrawal activate distinct signaling cascades that induce glycogen synthase kinase-3 beta and a caspase-9-dependent apoptosis in cerebellar granule neurons
description
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im Juli 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/07/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/07/01)
@nl
наукова стаття, опублікована в липні 2006
@uk
مقالة علمية (نشرت في يوليو 2006)
@ar
name
Endoplasmic reticulum stress a ...... in cerebellar granule neurons
@ast
Endoplasmic reticulum stress a ...... in cerebellar granule neurons
@en
Endoplasmic reticulum stress a ...... in cerebellar granule neurons
@nl
type
label
Endoplasmic reticulum stress a ...... in cerebellar granule neurons
@ast
Endoplasmic reticulum stress a ...... in cerebellar granule neurons
@en
Endoplasmic reticulum stress a ...... in cerebellar granule neurons
@nl
prefLabel
Endoplasmic reticulum stress a ...... in cerebellar granule neurons
@ast
Endoplasmic reticulum stress a ...... in cerebellar granule neurons
@en
Endoplasmic reticulum stress a ...... in cerebellar granule neurons
@nl
P2093
P921
P3181
P1476
Endoplasmic reticulum stress a ...... in cerebellar granule neurons
@en
P2093
D. A. Linseman
E. A. Esch
F. A. Loucks
J. L. Brewster
K. A. Heidenreich
R. J. Bouchard
T. A. Precht
P304
P3181
P356
10.1016/J.MCN.2006.04.006
P577
2006-07-01T00:00:00Z