Endoplasmic reticulum stress or mutation of an EF-hand Ca(2+)-binding domain directs the FKBP65 rotamase to an ERAD-based proteolysis
about
Structure of human peptidyl-prolylcis-transisomerase FKBP22 containing two EF-hand motifsNovel mutations in FKBP10 and PLOD2 cause rare Bruck syndrome in Chinese patientsFK506-Binding Protein 10, a Potential Novel Drug Target for Idiopathic Pulmonary FibrosisEndoplasmic Reticulum-Targeted Subunit Toxins Provide a New Approach to Rescue Misfolded Mutant Proteins and Revert Cell Models of Genetic Diseases.Absence of FKBP10 in recessive type XI osteogenesis imperfecta leads to diminished collagen cross-linking and reduced collagen deposition in extracellular matrix.Absence of the ER Cation Channel TMEM38B/TRIC-B Disrupts Intracellular Calcium Homeostasis and Dysregulates Collagen Synthesis in Recessive Osteogenesis Imperfecta.Heat shock protein 47 and 65 KDa FK506 binding protein weakly but synergistically interact during collagen folding in the endoplasmic reticulum.Pharmacological and biological therapeutic strategies for osteogenesis imperfecta.FKBP10 depletion enhances glucocerebrosidase proteostasis in Gaucher disease fibroblasts.Novel mutations in FKBP10 in Chinese patients with osteogenesis imperfecta and their treatment with zoledronic acid.
P2860
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P2860
Endoplasmic reticulum stress or mutation of an EF-hand Ca(2+)-binding domain directs the FKBP65 rotamase to an ERAD-based proteolysis
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Endoplasmic reticulum stress o ...... e to an ERAD-based proteolysis
@ast
Endoplasmic reticulum stress o ...... e to an ERAD-based proteolysis
@en
type
label
Endoplasmic reticulum stress o ...... e to an ERAD-based proteolysis
@ast
Endoplasmic reticulum stress o ...... e to an ERAD-based proteolysis
@en
prefLabel
Endoplasmic reticulum stress o ...... e to an ERAD-based proteolysis
@ast
Endoplasmic reticulum stress o ...... e to an ERAD-based proteolysis
@en
P2093
P2860
P1476
Endoplasmic reticulum stress o ...... e to an ERAD-based proteolysis
@en
P2093
Alexander M Herman
Emily A Ramirez
Jay L Brewster
Lindsey A Murphy
Valen C Anderson
Van T Trinh
P2860
P2888
P304
P356
10.1007/S12192-011-0270-X
P577
2011-07-15T00:00:00Z