Overexpression of cholesterol transporter StAR increases in vivo rates of bile acid synthesis in the rat and mouse
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Bile acids are nutrient signaling hormonesIdentification of novel regulatory cholesterol metabolite, 5-cholesten, 3β,25-diol, disulfateStAR overexpression decreases serum and tissue lipids in apolipoprotein E-deficient mice.Sulfation of 25-hydroxycholesterol by SULT2B1b decreases cellular lipids via the LXR/SREBP-1c signaling pathway in human aortic endothelial cells25-Hydroxycholesterol-3-sulfate attenuates inflammatory response via PPARγ signaling in human THP-1 macrophages.Oxysterol sulfation by cytosolic sulfotransferase suppresses liver X receptor/sterol regulatory element binding protein-1c signaling pathway and reduces serum and hepatic lipids in mouse models of nonalcoholic fatty liver disease.Macrophage-specific transgenic expression of cholesteryl ester hydrolase significantly reduces atherosclerosis and lesion necrosis in Ldlr mice.Cholesterol metabolite, 5-cholesten-3β-25-diol-3-sulfate, promotes hepatic proliferation in mice.25-Hydroxycholesterol-3-sulfate regulates macrophage lipid metabolism via the LXR/SREBP-1 signaling pathway.Hepatic bile acid metabolism in the neonatal hamster: expansion of the bile acid pool parallels increased Cyp7a1 expression levelsBile acids as regulatory molecules.Significance and mechanism of CYP7a1 gene regulation during the acute phase of liver regeneration.Sulfated oxysterol, 25HC3S, is a potent regulator of lipid metabolism in human hepatocytes.Sulfation of 25-hydroxycholesterol regulates lipid metabolism, inflammatory responses, and cell proliferation.Liver-specific transgenic expression of cholesteryl ester hydrolase reduces atherosclerosis in Ldlr-/- mice.Biliary cholesterol secretion: more than a simple ABC.Overexpression of the cholesterol-binding protein MLN64 induces liver damage in the mouse.Intracellular cholesterol transport proteins enhance hydrolysis of HDL-CEs and facilitate elimination of cholesterol into bileIdentification of a novel sulfonated oxysterol, 5-cholesten-3beta,25-diol 3-sulfonate, in hepatocyte nuclei and mitochondria.Enzyme activity assay for cholesterol 27-hydroxylase in mitochondria.Biosynthesis of the regulatory oxysterol, 5-cholesten-3beta,25-diol 3-sulfate, in hepatocytes.
P2860
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P2860
Overexpression of cholesterol transporter StAR increases in vivo rates of bile acid synthesis in the rat and mouse
description
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Oktober 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/10/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/10/01)
@nl
наукова стаття, опублікована в жовтні 2004
@uk
مقالة علمية (نشرت في أكتوبر 2004)
@ar
name
Overexpression of cholesterol ...... synthesis in the rat and mouse
@ast
Overexpression of cholesterol ...... synthesis in the rat and mouse
@en
Overexpression of cholesterol ...... synthesis in the rat and mouse
@nl
type
label
Overexpression of cholesterol ...... synthesis in the rat and mouse
@ast
Overexpression of cholesterol ...... synthesis in the rat and mouse
@en
Overexpression of cholesterol ...... synthesis in the rat and mouse
@nl
prefLabel
Overexpression of cholesterol ...... synthesis in the rat and mouse
@ast
Overexpression of cholesterol ...... synthesis in the rat and mouse
@en
Overexpression of cholesterol ...... synthesis in the rat and mouse
@nl
P2093
P356
P1433
P1476
Overexpression of cholesterol ...... synthesis in the rat and mouse
@en
P2093
Dalila Marques
Elizabeth Hall
Emily Gurley
Gregorio Gil
Kaye Redford
Patricia Bodhan
Phillip B. Hylemon
Shunlin Ren
William M. Pandak
P304
P356
10.1002/HEP.20382
P407
P577
2004-10-01T00:00:00Z