25-Hydroxycholesterol-3-sulfate regulates macrophage lipid metabolism via the LXR/SREBP-1 signaling pathway.
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Sterol metabolism controls T(H)17 differentiation by generating endogenous RORγ agonistsIdentification of novel regulatory cholesterol metabolite, 5-cholesten, 3β,25-diol, disulfateIbrolipim increases ABCA1/G1 expression by the LXRα signaling pathway in THP-1 macrophage-derived foam cells.The cholesterol metabolite 25-hydroxycholesterol activates estrogen receptor α-mediated signaling in cancer cells and in cardiomyocytes25-Hydroxycholesterol acts as an amplifier of inflammatory signaling.StAR overexpression decreases serum and tissue lipids in apolipoprotein E-deficient mice.Sulfation of 25-hydroxycholesterol by SULT2B1b decreases cellular lipids via the LXR/SREBP-1c signaling pathway in human aortic endothelial cellsA novel hypothesis for atherosclerosis as a cholesterol sulfate deficiency syndrome.25-Hydroxycholesterol-3-sulfate attenuates inflammatory response via PPARγ signaling in human THP-1 macrophages.Nanoparticles containing a liver X receptor agonist inhibit inflammation and atherosclerosisOxysterol sulfation by cytosolic sulfotransferase suppresses liver X receptor/sterol regulatory element binding protein-1c signaling pathway and reduces serum and hepatic lipids in mouse models of nonalcoholic fatty liver disease.Deciphering the roles of the constitutive androstane receptor in energy metabolism.Cytosolic sulfotransferase 2B1b promotes hepatocyte proliferation gene expression in vivo and in vitro.Cholesterol metabolite, 5-cholesten-3β-25-diol-3-sulfate, promotes hepatic proliferation in mice.5-cholesten-3β,25-diol 3-sulfate decreases lipid accumulation in diet-induced nonalcoholic fatty liver disease mouse modelBile acids as regulatory molecules.Sulfation of 25-hydroxycholesterol regulates lipid metabolism, inflammatory responses, and cell proliferation.Role of the constitutive androstane receptor in obesity and type 2 diabetes: a case study of the endobiotic function of a xenobiotic receptor.The challenges and promise of targeting the Liver X Receptors for treatment of inflammatory disease.Metabolism in Immune Cell Differentiation and Function.A novel transgenic mouse model of lysosomal storage disorderSemi-interpenetrating network (sIPN) co-electrospun gelatin/insulin fiber formulation for transbuccal insulin delivery.Polyphenol-rich apple extract inhibits dexamethasone-induced sebaceous lipids production by regulating SREBP1 expression.Transgenic Overexpression of Steroid Sulfatase Alleviates Cholestasis
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25-Hydroxycholesterol-3-sulfate regulates macrophage lipid metabolism via the LXR/SREBP-1 signaling pathway.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 14 October 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
25-Hydroxycholesterol-3-sulfat ...... LXR/SREBP-1 signaling pathway.
@en
25-Hydroxycholesterol-3-sulfat ...... LXR/SREBP-1 signaling pathway.
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type
label
25-Hydroxycholesterol-3-sulfat ...... LXR/SREBP-1 signaling pathway.
@en
25-Hydroxycholesterol-3-sulfat ...... LXR/SREBP-1 signaling pathway.
@nl
prefLabel
25-Hydroxycholesterol-3-sulfat ...... LXR/SREBP-1 signaling pathway.
@en
25-Hydroxycholesterol-3-sulfat ...... LXR/SREBP-1 signaling pathway.
@nl
P2093
P2860
P1476
25-Hydroxycholesterol-3-sulfat ...... LXR/SREBP-1 signaling pathway
@en
P2093
Daniel Rodriguez-Agudo
Douglas M Heuman
Phillip B Hylemon
Shunlin Ren
William M Pandak
Yongjie Ma
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P304
P356
10.1152/AJPENDO.90555.2008
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P577
2008-10-14T00:00:00Z