Distinct structural and functional properties of the ATPase sites in an asymmetric ABC transporter
about
Structure, function, and evolution of bacterial ATP-binding cassette systemsStructures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutantSnapshots of the maltose transporter during ATP hydrolysisCrystal structure of a heterodimeric ABC transporter in its inward-facing conformationStructure of AMP-PNP-bound vitamin B12 transporter BtuCD-FViral inhibition of the transporter associated with antigen processing (TAP): a striking example of functional convergent evolutionThe ATP-binding cassette proteins of the deep-branching protozoan parasite Trichomonas vaginalisCatalytic and transport cycles of ABC exporters.Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter.Asymmetric switching in a homodimeric ABC transporter: a simulation studyConformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter.A highly conserved sequence of the viral TAP inhibitor ICP47 is required for freezing of the peptide transport cycleAsymmetric ATP hydrolysis cycle of the heterodimeric multidrug ABC transport complex TmrAB from Thermus thermophilus.Stable ATP binding mediated by a partial NBD dimer of the CFTR chloride channelDivergent signature motifs of nucleotide binding domains of ABC multidrug transporter, CaCdr1p of pathogenic Candida albicans, are functionally asymmetric and noninterchangeableThe hydroxyl group of S685 in Walker A motif and the carboxyl group of D792 in Walker B motif of NBD1 play a crucial role for multidrug resistance protein folding and function.Optimization of the degenerated interfacial ATP binding site improves the function of disease-related mutant cystic fibrosis transmembrane conductance regulator (CFTR) channels.Functional hot spots in human ATP-binding cassette transporter nucleotide binding domains.Protein contacts and ligand binding in the inward-facing model of human P-glycoprotein.An asymmetric post-hydrolysis state of the ABC transporter ATPase dimer.Glutamine residues in Q-loops of multidrug resistance protein MRP1 contribute to ATP binding via interaction with metal cofactorMutant cycles at CFTR's non-canonical ATP-binding site support little interface separation during gatingInhibition of multidrug resistance-linked P-glycoprotein (ABCB1) function by 5'-fluorosulfonylbenzoyl 5'-adenosine: evidence for an ATP analogue that interacts with both drug-substrate-and nucleotide-binding sitesIn vitro reassembly of the ribose ATP-binding cassette transporter reveals a distinct set of transport complexes.Reaction chemistry ABC-style.Cysteine accessibility probes timing and extent of NBD separation along the dimer interface in gating CFTR channels.Interaction between the bound Mg.ATP and the Walker A serine residue in NBD2 of multidrug resistance-associated protein MRP1 plays a crucial role for the ATP-dependent leukotriene C4 transportThe Heterodimeric ABC Transporter EfrCD Mediates Multidrug Efflux in Enterococcus faecalis.Molecular modelling and molecular dynamics of CFTR.Use of Functional Polymorphisms To Elucidate the Peptide Binding Site of TAP Complexes.D-helix influences dimerization of the ATP-binding cassette (ABC) transporter associated with antigen processing 1 (TAP1) nucleotide-binding domainA mutation of the H-loop selectively affects rhodamine transport by the yeast multidrug ABC transporter Pdr5.The multidrug transporter Pdr5 on the 25th anniversary of its discovery: an important model for the study of asymmetric ABC transportersOn the origin of large flexibility of P-glycoprotein in the inward-facing stateMutations in the Arabidopsis peroxisomal ABC transporter COMATOSE allow differentiation between multiple functions in planta: insights from an allelic series.CLC-0 and CFTR: chloride channels evolved from transporters.Toward Determining ATPase Mechanism in ABC Transporters: Development of the Reaction Path-Force Matching QM/MM Method.MHC class I assembly: out and about.Asymmetric conformational flexibility in the ATP-binding cassette transporter HI1470/1.Review. ATP hydrolysis-driven gating in cystic fibrosis transmembrane conductance regulator.
P2860
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P2860
Distinct structural and functional properties of the ATPase sites in an asymmetric ABC transporter
description
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im Oktober 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/10/06)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/10/06)
@nl
наукова стаття, опублікована в жовтні 2006
@uk
مقالة علمية (نشرت في 6-10-2006)
@ar
name
Distinct structural and functi ...... an asymmetric ABC transporter
@ast
Distinct structural and functi ...... an asymmetric ABC transporter
@en
Distinct structural and functi ...... an asymmetric ABC transporter
@nl
type
label
Distinct structural and functi ...... an asymmetric ABC transporter
@ast
Distinct structural and functi ...... an asymmetric ABC transporter
@en
Distinct structural and functi ...... an asymmetric ABC transporter
@nl
prefLabel
Distinct structural and functi ...... an asymmetric ABC transporter
@ast
Distinct structural and functi ...... an asymmetric ABC transporter
@en
Distinct structural and functi ...... an asymmetric ABC transporter
@nl
P50
P3181
P1433
P1476
Distinct structural and functi ...... an asymmetric ABC transporter
@en
P2093
Sze-Ling Ng
P3181
P356
10.1016/J.MOLCEL.2006.07.034
P577
2006-10-06T00:00:00Z