Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
about
Running out of time: the decline of channel activity and nucleotide activation in adenosine triphosphate-sensitive K-channelsCancer drug resistance: redox resetting renders a wayThe Nucleotide-Binding Sites of SUR1: A Mechanistic ModelInverted topologies in membrane proteins: a mini-reviewMammalian P4-ATPases and ABC transporters and their role in phospholipid transportStructures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound statesStructures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domainStructural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog.Structural Basis for Heavy Metal Detoxification by an Atm1-Type ABC ExporterStructural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter.Plausible Drug Targets in the Streptococcus mutans Quorum Sensing Pathways to Combat Dental Biofilms and Associated RisksViral inhibition of the transporter associated with antigen processing (TAP): a striking example of functional convergent evolutionJump into a New Fold-A Homology Based Model for the ABCG2/BCRP Multidrug TransporterDevelopment of CFTR StructureMissense mutations in the ABCB6 transporter cause dominant familial pseudohyperkalemia.Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporterStructural basis of inhibition of lipid-linked oligosaccharide flippase PglK by a conformational nanobody.Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter.Structural Symmetry in Membrane Proteins.Structural diversity of ABC transporters.Modeling the conformational changes underlying channel opening in CFTRStructural characterization of two metastable ATP-bound states of P-glycoprotein.In vitro reassembly of the ribose ATP-binding cassette transporter reveals a distinct set of transport complexes.Localizing a gate in CFTR.Distinct conformational spectrum of homologous multidrug ABC transporters.Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein.Cysteine accessibility probes timing and extent of NBD separation along the dimer interface in gating CFTR channels.Full-open and closed CFTR channels, with lateral tunnels from the cytoplasm and an alternative position of the F508 region, as revealed by molecular dynamics.Stubborn contaminants: influence of detergents on the purity of the multidrug ABC transporter BmrA.Efficient and stable reconstitution of the ABC transporter BmrA for solid-state NMR studiesATP Binding and Hydrolysis Properties of ABCB10 and Their Regulation by Glutathione.The Heterodimeric ABC Transporter EfrCD Mediates Multidrug Efflux in Enterococcus faecalis.Molecular modelling and molecular dynamics of CFTR.Use of Functional Polymorphisms To Elucidate the Peptide Binding Site of TAP Complexes.D-helix influences dimerization of the ATP-binding cassette (ABC) transporter associated with antigen processing 1 (TAP1) nucleotide-binding domainTransmembrane helical interactions in the CFTR channel pore.The ATPases of cohesin interface with regulators to modulate cohesin-mediated DNA tethering.Cysteine scanning of CFTR's first transmembrane segment reveals its plausible roles in gating and permeationPositioning of extracellular loop 1 affects pore gating of the cystic fibrosis transmembrane conductance regulatorThe multidrug transporter Pdr5 on the 25th anniversary of its discovery: an important model for the study of asymmetric ABC transporters
P2860
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P2860
Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
@ast
Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
@en
Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
@nl
type
label
Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
@ast
Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
@en
Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
@nl
prefLabel
Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
@ast
Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
@en
Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
@nl
P2093
P2860
P3181
P356
P1476
Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
@en
P2093
Christophe Briand
Markus A Seeger
Markus G Grütter
P2860
P2888
P304
P3181
P356
10.1038/NSMB.2267
P50
P577
2012-03-25T00:00:00Z
P6179
1011202545