AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes
about
Myomegalin is a novel A-kinase anchoring protein involved in the phosphorylation of cardiac myosin binding protein CSphingosine kinase interacting protein is an A-kinase anchoring protein specific for type I cAMP-dependent protein kinaseα-Synemin localizes to the M-band of the sarcomere through interaction with the M10 region of titinBioinformatic design of A-kinase anchoring protein-in silico: a potent and selective peptide antagonist of type II protein kinase A anchoringAmino acid variant in the kinase binding domain of dual-specific A kinase-anchoring protein 2: a disease susceptibility polymorphismCompartmentalization role of A-kinase anchoring proteins (AKAPs) in mediating protein kinase A (PKA) signaling and cardiomyocyte hypertrophyNetworking with AKAPs: context-dependent regulation of anchored enzymesDelocalization of Endogenous A-kinase Antagonizes Rap1-Rho-α2C-Adrenoceptor Signaling in Human Microvascular Smooth Muscle CellsAn adenylyl cyclase-mAKAPbeta signaling complex regulates cAMP levels in cardiac myocytesAKAP-Lbc mobilizes a cardiac hypertrophy signaling pathwaySmall molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytesTargeting of protein kinase A by muscle A kinase-anchoring protein (mAKAP) regulates phosphorylation and function of the skeletal muscle ryanodine receptorPKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to β-adrenergic signalingDisruption of protein kinase A localization using a trans-activator of transcription (TAT)-conjugated A-kinase-anchoring peptide reduces cardiac function.Elevated Ca2+ sparklet activity during acute hyperglycemia and diabetes in cerebral arterial smooth muscle cells.Cardiac troponin T, a sarcomeric AKAP, tethers protein kinase A at the myofilaments.Compartmentalized PKA signaling events are required for synaptic tagging and capture during hippocampal late-phase long-term potentiationGenetic disruption of protein kinase A anchoring reveals a role for compartmentalized kinase signaling in theta-burst long-term potentiation and spatial memory.Chromodomain helicase binding protein 8 (Chd8) is a novel A-kinase anchoring protein expressed during rat cardiac development.Identification of the interface between cGMP-dependent protein kinase Ibeta and its interaction partners TFII-I and IRAG reveals a common interaction motif.Enhanced cardiac function in Gravin mutant mice involves alterations in the β-adrenergic receptor signaling cascadeSystems analysis of PKA-mediated phosphorylation gradients in live cardiac myocytesAKAPs: the architectural underpinnings of local cAMP signaling.A full range of mouse sinoatrial node AP firing rates requires protein kinase A-dependent calcium signaling.A kinase-anchoring proteins and adenylyl cyclase in cardiovascular physiology and pathology.A-kinase anchoring proteins: scaffolding proteins in the heart.Glycogen autophagy.Anchoring proteins as regulators of signaling pathways.Molecular evolution of A-kinase anchoring protein (AKAP)-7: implications in comparative PKA compartmentalization.Creating order from chaos: cellular regulation by kinase anchoring.Phosphorylation state-dependent interaction between AKAP7δ/γ and phospholamban increases phospholamban phosphorylation.Spatial control of the βAR system in heart failure: the transverse tubule and beyond.Motif-specific sampling of phosphoproteomes.Protein kinase A and phosphodiesterase-4D3 binding to coding polymorphisms of cardiac muscle anchoring protein (mAKAP).Designing heart performance by gene transfer.Ethanol Extract of Lepidium apetalum Seed Elicits Contractile Response and Attenuates Atrial Natriuretic Peptide Secretion in Beating Rabbit Atria.Beta-adrenergic stimulation and myocardial function in the failing heart.AKAP-scaffolding proteins and regulation of cardiac physiology.Mapping the protein phosphatase-2B anchoring site on AKAP79. Binding and inhibition of phosphatase activity are mediated by residues 315-360.A-kinase anchoring proteins: getting to the heart of the matter.
P2860
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P2860
AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes
description
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im Februar 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/02/16)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/02/16)
@nl
наукова стаття, опублікована в лютому 2001
@uk
مقالة علمية (نشرت في 16-2-2001)
@ar
name
AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes
@ast
AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes
@en
AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes
@nl
type
label
AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes
@ast
AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes
@en
AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes
@nl
prefLabel
AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes
@ast
AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes
@en
AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes
@nl
P2093
P356
P1433
P1476
AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes
@en
P2093
C Apperson-Hansen
D S Damron
J A Mackey
R W Desnoyer
P304
P356
10.1161/01.RES.88.3.291
P50
P577
2001-02-01T00:00:00Z