Mapping the protein phosphatase-2B anchoring site on AKAP79. Binding and inhibition of phosphatase activity are mediated by residues 315-360.
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Direct association of the unique C-terminal tail of transmembrane AMPA receptor regulatory protein γ-8 with calcineurinProtein kinase A regulates AKAP250 (gravin) scaffold binding to the beta2-adrenergic receptorTherapeutic strategies for anchored kinases and phosphatases: exploiting short linear motifs and intrinsic disorderSyndecan-4 is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin-NFAT pathwayBalanced interactions of calcineurin with AKAP79 regulate Ca2+–calcineurin–NFAT signalingSsh4, Rcr2 and Rcr1 affect plasma membrane transporter activity in Saccharomyces cerevisiae.Regulation of the phosphatase PP2B by protein-protein interactionsNetworking with AKAPs: context-dependent regulation of anchored enzymesPhosphodiesterase 10A Is Tethered to a Synaptic Signaling Complex in StriatumAnchored phosphatases modulate glucose homeostasisSingle Turnover Autophosphorylation Cycle of the PKA RIIβ HoloenzymeAKAP79/150 anchoring of calcineurin controls neuronal L-type Ca2+ channel activity and nuclear signalingAssociation of an A-kinase-anchoring protein signaling scaffold with cadherin adhesion molecules in neurons and epithelial cellsRegulation of postsynaptic structure and function by an A-kinase anchoring protein-membrane-associated guanylate kinase scaffolding complexA critical role for PSD-95/AKAP interactions in endocytosis of synaptic AMPA receptorsCa2+/calmodulin-dependent protein kinase II binds to and phosphorylates a specific SAP97 splice variant to disrupt association with AKAP79/150 and modulate alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate receptor (AMPAR) actiDecreased expression of A-kinase anchoring protein 150 in GT1 neurons decreases neuron excitability and frequency of intrinsic gonadotropin-releasing hormone pulses.The flagellar motility of Chlamydomonas pf25 mutant lacking an AKAP-binding protein is overtly sensitive to medium conditions.Mutations in AKAP5 disrupt dendritic signaling complexes and lead to electrophysiological and behavioral phenotypes in mice.AKAP79 interacts with multiple adenylyl cyclase (AC) isoforms and scaffolds AC5 and -6 to alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) receptors.A calcineurin/AKAP complex is required for NMDA receptor-dependent long-term depression.The linker region joining the catalytic and the regulatory domains of CnA is essential for binding to NFAT.Mapping the binding site of TRPV1 on AKAP79: implications for inflammatory hyperalgesia.Striatal-enriched protein tyrosine phosphatase regulates the PTPα/Fyn signaling pathwayAKAP79/150 impacts intrinsic excitability of hippocampal neurons through phospho-regulation of A-type K+ channel trafficking.PP2B/calcineurin-mediated desensitization of TRPV1 does not require AKAP150.Ca2+/calmodulin-dependent protein kinase II inhibitors disrupt AKAP79-dependent PKC signaling to GluA1 AMPA receptors.Slm1 and slm2 are novel substrates of the calcineurin phosphatase required for heat stress-induced endocytosis of the yeast uracil permease.Architecture and dynamics of an A-kinase anchoring protein 79 (AKAP79) signaling complexCarvedilol reverses cardiac insufficiency in AKAP5 knockout mice by normalizing the activities of calcineurin and CaMKII.Identification of AKAP79 as a protein phosphatase 1 catalytic binding proteinA kinase anchor protein 150 (AKAP150)-associated protein kinase A limits dendritic spine density.The role of serine/threonine protein phosphatases in exocytosisAKAPs (A-kinase anchoring proteins) and molecules that compose their G-protein-coupled receptor signalling complexes.Inhibition of the NFAT pathway alleviates amyloid β neurotoxicity in a mouse model of Alzheimer's disease.Protein Kinase C (PKC)ζ Pseudosubstrate Inhibitor Peptide Promiscuously Binds PKC Family Isoforms and Disrupts Conventional PKC Targeting and Translocation.Organization of beta-adrenoceptor signaling compartments by sympathetic innervation of cardiac myocytes.Imaging kinase--AKAP79--phosphatase scaffold complexes at the plasma membrane in living cells using FRET microscopy.Coordination of Protein Phosphorylation and Dephosphorylation in Synaptic Plasticity"Shaping" of cell signaling via AKAP-tethered PDE4D: Probing with AKAR2-AKAP5 biosensor.
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P2860
Mapping the protein phosphatase-2B anchoring site on AKAP79. Binding and inhibition of phosphatase activity are mediated by residues 315-360.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 26 September 2002
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Mapping the protein phosphatas ...... mediated by residues 315-360.
@en
Mapping the protein phosphatas ...... mediated by residues 315-360.
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type
label
Mapping the protein phosphatas ...... mediated by residues 315-360.
@en
Mapping the protein phosphatas ...... mediated by residues 315-360.
@nl
prefLabel
Mapping the protein phosphatas ...... mediated by residues 315-360.
@en
Mapping the protein phosphatas ...... mediated by residues 315-360.
@nl
P2093
P2860
P356
P1476
Mapping the protein phosphatas ...... e mediated by residues 315-360
@en
P2093
John D Scott
Kimberly L Dodge
Steven J Tavalin
P2860
P304
48796-48802
P356
10.1074/JBC.M207833200
P407
P577
2002-09-26T00:00:00Z