Synaptojanin 2, a novel synaptojanin isoform with a distinct targeting domain and expression pattern
about
Identification and characterization of a novel inositol polyphosphate 5-phosphataseThe human phosphatidylinositol phosphatase SAC1 interacts with the coatomer I complexSynaptojanin 1: localization on coated endocytic intermediates in nerve terminals and interaction of its 170 kDa isoform with Eps15Expression and protein-binding studies of the EEN gene family, new interacting partners for dynamin, synaptojanin and huntingtin proteinsRecruitment of an alternatively spliced form of synaptojanin 2 to mitochondria by the interaction with the PDZ domain of a mitochondrial outer membrane protein.The BAR domain proteins: molding membranes in fission, fusion, and phagyInteraction between PAK and nck: a template for Nck targets and role of PAK autophosphorylationEpsin 1 undergoes nucleocytosolic shuttling and its eps15 interactor NH(2)-terminal homology (ENTH) domain, structurally similar to Armadillo and HEAT repeats, interacts with the transcription factor promyelocytic leukemia Zn(2)+ finger protein (PLZPhosphoinositides: tiny lipids with giant impact on cell regulationSac2/INPP5F is an inositol 4-phosphatase that functions in the endocytic pathway.The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminalsThe SH3 domains of endophilin and amphiphysin bind to the proline-rich region of synaptojanin 1 at distinct sites that display an unconventional binding specificityIdentification and characterization of a synaptojanin 2 splice isoform predominantly expressed in nerve terminalsFunctional characterization of a mammalian Sac1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activityrSac3, a novel Sac domain phosphoinositide phosphatase, promotes neurite outgrowth in PC12 cellsNovel inositol polyphosphate 5-phosphatase localizes at membrane rufflesEndocytosis of epidermal growth factor receptor regulated by Grb2-mediated recruitment of the Rab5 GTPase-activating protein RN-tre.Deletion of a proline-rich region and a transmembrane domain in fatty acid amide hydrolase.A mutation in synaptojanin 2 causes progressive hearing loss in the ENU-mutagenised mouse strain Mozart.Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice.Kinetic analysis of receptor-activated phosphoinositide turnoverSynaptojanin 2 is recognized by HLA class II-restricted hairy cell leukemia-specific T cells.The role of phosphatases in inositol signaling reactions.Phosphoinositide phosphatases in cell biology and disease.Mutations in Serac1 or Synj2 cause proximal t haplotype-mediated male mouse sterility but not transmission ratio distortion.Longevity candidate genes and their association with personality traits in the elderly.Regulation of synaptojanin 2 5'-phosphatase activity by SrcMitogenesis and endocytosis: What's at the INTERSECTIoN?Role of the guanine nucleotide exchange factor Ost in negative regulation of receptor endocytosis by the small GTPase Rac1.Differential role for synaptojanin 1 in rod and cone photoreceptors.Role of phosphatidylinositol 4,5-bisphosphate in regulating EHD2 plasma membrane localizationThe structure of phosphoinositide phosphatases: Insights into substrate specificity and catalysis.Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancer.Evolutionary conserved longevity genes and human cognitive abilities in elderly cohorts.Eps15 homology domain 1-associated tubules contain phosphatidylinositol-4-phosphate and phosphatidylinositol-(4,5)-bisphosphate and are required for efficient recycling.The Sac1 domain of SYNJ1 identified mutated in a family with early-onset progressive Parkinsonism with generalized seizuresInositol lipid phosphatases in membrane trafficking and human disease.Phosphatidylinositolphosphate phosphatase activities and cancer.Molecular aspects of the endocytic pathway.Analysis of an intronic promoter within Synj2.
P2860
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P2860
Synaptojanin 2, a novel synaptojanin isoform with a distinct targeting domain and expression pattern
description
1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1997
@ast
im Dezember 1997 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1997/12/05)
@sk
vědecký článek publikovaný v roce 1997
@cs
wetenschappelijk artikel (gepubliceerd op 1997/12/05)
@nl
наукова стаття, опублікована в грудні 1997
@uk
name
Synaptojanin 2, a novel synapt ...... domain and expression pattern
@ast
Synaptojanin 2, a novel synapt ...... domain and expression pattern
@en
Synaptojanin 2, a novel synapt ...... domain and expression pattern
@nl
type
label
Synaptojanin 2, a novel synapt ...... domain and expression pattern
@ast
Synaptojanin 2, a novel synapt ...... domain and expression pattern
@en
Synaptojanin 2, a novel synapt ...... domain and expression pattern
@nl
prefLabel
Synaptojanin 2, a novel synapt ...... domain and expression pattern
@ast
Synaptojanin 2, a novel synapt ...... domain and expression pattern
@en
Synaptojanin 2, a novel synapt ...... domain and expression pattern
@nl
P2093
P356
P1476
Synaptojanin 2, a novel synapt ...... domain and expression pattern
@en
P2093
C. Haffner
M. Arribas
P. DeCamilli
P304
30817–30821
P356
10.1074/JBC.272.49.30817
P407
P577
1997-12-05T00:00:00Z