Competition between thyroid hormone receptor-associated protein (TRAP) 220 and transcriptional intermediary factor (TIF) 2 for binding to nuclear receptors. Implications for the recruitment of TRAP and p160 coactivator complexes
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CIA, a novel estrogen receptor coactivator with a bifunctional nuclear receptor interacting determinantA coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expressionThe DRIP complex and SRC-1/p160 coactivators share similar nuclear receptor binding determinants but constitute functionally distinct complexesThe orphan nuclear receptor SHP utilizes conserved LXXLL-related motifs for interactions with ligand-activated estrogen receptorsCloning and characterization of RAP250, a novel nuclear receptor coactivatorA model for aryl hydrocarbon receptor-activated gene expression shows potency and efficacy changes and predicts squelching due to competition for transcription co-activatorsInactivation of the nuclear receptor coactivator RAP250 in mice results in placental vascular dysfunction.Structural and functional organization of TRAP220, the TRAP/mediator subunit that is targeted by nuclear receptorsThe focal adhesion protein vinexin alpha regulates the phosphorylation and activity of estrogen receptor alpha.Liver X receptor ligands suppress ubiquitination and degradation of LXRalpha by displacing BARD1/BRCA1.MED14 tethers mediator to the N-terminal domain of peroxisome proliferator-activated receptor gamma and is required for full transcriptional activity and adipogenesis.Aryl hydrocarbon receptor-mediated transcription: ligand-dependent recruitment of estrogen receptor alpha to 2,3,7,8-tetrachlorodibenzo-p-dioxin-responsive promoters.Specific structural motifs determine TRAP220 interactions with nuclear hormone receptors.Use of suppressor mutants to probe the function of estrogen receptor-p160 coactivator interactions.Understanding large multiprotein complexes: applying a multiple allosteric networks model to explain the function of the Mediator transcription complex.Estrogen receptors: orchestrators of pleiotropic cellular responses.Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification.MED1 mediates androgen receptor splice variant induced gene expression in the absence of ligandMediator subunit MED1 is a T3-dependent and T3-independent coactivator on the thyrotropin β gene promoter.Dynamic interactions and cooperative functions of PGC-1alpha and MED1 in TRalpha-mediated activation of the brown-fat-specific UCP-1 geneCoactivation of estrogen receptor alpha (ER alpha)/Sp1 by vitamin D receptor interacting protein 150 (DRIP150).Alternative mechanisms by which mediator subunit MED1/TRAP220 regulates peroxisome proliferator-activated receptor gamma-stimulated adipogenesis and target gene expression.Estrogen signaling multiple pathways to impact gene transcription.Vitamin D-interacting protein 205 (DRIP205) coactivation of estrogen receptor alpha (ERalpha) involves multiple domains of both proteins.Discrete roles for peroxisome proliferator-activated receptor gamma and retinoid X receptor in recruiting nuclear receptor coactivators.p300 requires its histone acetyltransferase activity and SRC-1 interaction domain to facilitate thyroid hormone receptor activation in chromatin.Triiodothyronine increases brain natriuretic peptide (BNP) gene transcription and amplifies endothelin-dependent BNP gene transcription and hypertrophy in neonatal rat ventricular myocytes.
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Competition between thyroid hormone receptor-associated protein (TRAP) 220 and transcriptional intermediary factor (TIF) 2 for binding to nuclear receptors. Implications for the recruitment of TRAP and p160 coactivator complexes
description
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1999
@ast
im März 1999 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1999/03/05)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/03/05)
@nl
наукова стаття, опублікована в березні 1999
@uk
name
Competition between thyroid ho ...... and p160 coactivator complexes
@ast
Competition between thyroid ho ...... and p160 coactivator complexes
@en
Competition between thyroid ho ...... and p160 coactivator complexes
@nl
type
label
Competition between thyroid ho ...... and p160 coactivator complexes
@ast
Competition between thyroid ho ...... and p160 coactivator complexes
@en
Competition between thyroid ho ...... and p160 coactivator complexes
@nl
prefLabel
Competition between thyroid ho ...... and p160 coactivator complexes
@ast
Competition between thyroid ho ...... and p160 coactivator complexes
@en
Competition between thyroid ho ...... and p160 coactivator complexes
@nl
P2093
P2860
P356
P1476
Competition between thyroid ho ...... and p160 coactivator complexes
@en
P2093
A. P. Wright
A. Wärnmark
E. Treuter
J. A. Gustafsson
J. S. Thomsen
L. Johansson
M. Pelto-Huikko
M. Sjöberg
P2860
P304
P356
10.1074/JBC.274.10.6667
P407
P577
1999-03-05T00:00:00Z