Identification of conserved amino acid residues in rat liver carnitine palmitoyltransferase I critical for malonyl-CoA inhibition. Mutation of methionine 593 abolishes malonyl-CoA inhibition
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Fatty acid metabolism and the basis of brown adipose tissue functionMitochondrial fatty acid oxidation in obesityAn Environment-dependent Structural Switch Underlies the Regulation of Carnitine Palmitoyltransferase 1ADefinition by functional and structural analysis of two malonyl-CoA sites in carnitine palmitoyltransferase 1ARedesign of carnitine acetyltransferase specificity by protein engineeringModulation of the hepatic malonyl-CoA-carnitine palmitoyltransferase 1A partnership creates a metabolic switch allowing oxidation of de novo fatty acidsCPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activityPhosphorylation of rat liver mitochondrial carnitine palmitoyltransferase-I: effect on the kinetic properties of the enzymeProtein co-evolution: how do we combine bioinformatics and experimental approaches?Protein interactions and ligand binding: from protein subfamilies to functional specificity.Alternative exon usage in the single CPT1 gene of Drosophila generates functional diversity in the kinetic properties of the enzyme: differential expression of alternatively spliced variants in Drosophila tissues.JDet: interactive calculation and visualization of function-related conservation patterns in multiple sequence alignments and structures.Increased mitochondrial fatty acid oxidation is sufficient to protect skeletal muscle cells from palmitate-induced apoptosisEnhancing hepatic mitochondrial fatty acid oxidation stimulates eating in food-deprived mice.Long-term increased carnitine palmitoyltransferase 1A expression in ventromedial hypotalamus causes hyperphagia and alters the hypothalamic lipidomic profileTight coevolution of proliferating cell nuclear antigen (PCNA)-partner interaction networks in fungi leads to interspecies network incompatibilityCarnitine Palmitoyltransferase 1 Increases Lipolysis, UCP1 Protein Expression and Mitochondrial Activity in Brown Adipocytes.Malonyl-CoA mediates leptin hypothalamic control of feeding independent of inhibition of CPT-1aHypothalamic malonyl-coenzyme A and the control of energy balance.Carnitine palmitoyltransferase IA polymorphism P479L is common in Greenland Inuit and is associated with elevated plasma apolipoprotein A-IPractical analysis of specificity-determining residues in protein families.Differential pharmacologic properties of the two C75 enantiomers: (+)-C75 is a strong anorectic drug; (-)-C75 has antitumor activity.A Novel Mutation in CPT1A Resulting in Hepatic CPT Deficiency.Genome duplication events have led to a diversification in the CPT I gene family in fish.Important role of ventromedial hypothalamic carnitine palmitoyltransferase-1a in the control of food intake.The Carnitine Palmitoyl Transferase (CPT) System and Possible Relevance for Neuropsychiatric and Neurological Conditions.Functional and structural basis of carnitine palmitoyltransferase 1A deficiency.
P2860
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P2860
Identification of conserved amino acid residues in rat liver carnitine palmitoyltransferase I critical for malonyl-CoA inhibition. Mutation of methionine 593 abolishes malonyl-CoA inhibition
description
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2003
@ast
im März 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/03/14)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/03/14)
@nl
наукова стаття, опублікована в березні 2003
@uk
name
Identification of conserved am ...... olishes malonyl-CoA inhibition
@ast
Identification of conserved am ...... olishes malonyl-CoA inhibition
@en
Identification of conserved am ...... olishes malonyl-CoA inhibition
@nl
type
label
Identification of conserved am ...... olishes malonyl-CoA inhibition
@ast
Identification of conserved am ...... olishes malonyl-CoA inhibition
@en
Identification of conserved am ...... olishes malonyl-CoA inhibition
@nl
prefLabel
Identification of conserved am ...... olishes malonyl-CoA inhibition
@ast
Identification of conserved am ...... olishes malonyl-CoA inhibition
@en
Identification of conserved am ...... olishes malonyl-CoA inhibition
@nl
P2093
P2860
P3181
P356
P1476
Identification of conserved am ...... olishes malonyl-CoA inhibition
@en
P2093
Alfonso Valencia
Assia Bentebibel
Dolors Serra
Eva Sellés
Fausto G. Hegardt
Guillermina Asins
Montserrat Morillas
Nuria Casals
Paulino Gómez-Puertas
P2860
P304
P3181
P356
10.1074/JBC.M209999200
P407
P577
2003-03-14T00:00:00Z