CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity
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Mutation in CPT1C Associated With Pure Autosomal Dominant Spastic ParaplegiaFatty acid metabolism and the basis of brown adipose tissue functionFatty acid oxidation and carnitine palmitoyltransferase I: emerging therapeutic targets in cancerAcylcarnitines: reflecting or inflicting insulin resistance?Hypothalamic malonyl-CoA and the control of food intakeStructural characterization of the regulatory domain of brain carnitine palmitoyltransferase 1Increasing fatty acid oxidation remodels the hypothalamic neurometabolome to mitigate stress and inflammationThe cellular and molecular bases of leptin and ghrelin resistance in obesity.Alternative exon usage in the single CPT1 gene of Drosophila generates functional diversity in the kinetic properties of the enzyme: differential expression of alternatively spliced variants in Drosophila tissues.AMPA-receptor specific biogenesis complexes control synaptic transmission and intellectual ability.The CPT1C 5'UTR contains a repressing upstream open reading frame that is regulated by cellular energy availability and AMPKTargeting of mitochondria-endoplasmic reticulum by fluorescent macrocyclic compounds.Metabolomic profiling reveals a role for CPT1c in neuronal oxidative metabolismCarnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress.Important roles of brain-specific carnitine palmitoyltransferase and ceramide metabolism in leptin hypothalamic control of feedingEnteric neuropathy can be induced by high fat diet in vivo and palmitic acid exposure in vitro.Long-term increased carnitine palmitoyltransferase 1A expression in ventromedial hypotalamus causes hyperphagia and alters the hypothalamic lipidomic profileDifferentially expressed genes in adipocytokine signaling pathway of adipose tissue in pregnancy.The Origin and Diversity of Cpt1 Genes in Vertebrate Species.Ceramide levels regulated by carnitine palmitoyltransferase 1C control dendritic spine maturation and cognition.Role of Hypothalamic Creb-Binding Protein in Obesity and Molecular Reprogramming of Metabolic SubstratesPLXNC1 and RDH13 associated with bilateral convergent strabismus with exophthalmus in German Brown cattleDepletion of the novel p53-target gene carnitine palmitoyltransferase 1C delays tumor growth in the neurofibromatosis type I tumor modelCarnitine palmitoyltransferase 1A functions to repress FoxO transcription factors to allow cell cycle progression in ovarian cancer.Hypothalamic ceramide levels regulated by CPT1C mediate the orexigenic effect of ghrelin.Palmitoylation of amyloid precursor protein regulates amyloidogenic processing in lipid raftsCancer metabolism: fatty acid oxidation in the limelight.Carnitine palmitoyl transferase-1A (CPT1A): a new tumor specific target in human breast cancer.Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity.Interaction proteomics of the AMPA receptor: towards identification of receptor sub-complexes.Targeting lipid sensing in the central nervous system: new therapy against the development of obesity and type 2 diabetes.The role of hypothalamic H1 receptor antagonism in antipsychotic-induced weight gain.PPARα regulates tumor cell proliferation and senescence via a novel target gene carnitine palmitoyltransferase 1C.Elevated expression of fatty acid synthase and nuclear localization of carnitine palmitoyltransferase 1C are common among human gliomas.Glucose regulates hypothalamic long-chain fatty acid metabolism via AMP-activated kinase (AMPK) in neurons and astrocytesPalmitoylation regulates the intracellular trafficking and stability of c-Met.Hhat is a palmitoylacyltransferase with specificity for N-palmitoylation of Sonic Hedgehog.Novel Regulation of the Synthesis of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Subunit GluA1 by Carnitine Palmitoyltransferase 1C (CPT1C) in the Hippocampus.AMPAR interacting protein CPT1C enhances surface expression of GluA1-containing receptors.Carnitine palmitoyltransferase-1c gain-of-function in the brain results in postnatal microencephaly.
P2860
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P2860
CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity
description
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2008
@ast
im März 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/03/14)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/03/14)
@nl
наукова стаття, опублікована в березні 2008
@uk
name
CPT1c is localized in endoplas ...... palmitoyltransferase activity
@ast
CPT1c is localized in endoplas ...... palmitoyltransferase activity
@en
CPT1c is localized in endoplas ...... palmitoyltransferase activity
@nl
type
label
CPT1c is localized in endoplas ...... palmitoyltransferase activity
@ast
CPT1c is localized in endoplas ...... palmitoyltransferase activity
@en
CPT1c is localized in endoplas ...... palmitoyltransferase activity
@nl
prefLabel
CPT1c is localized in endoplas ...... palmitoyltransferase activity
@ast
CPT1c is localized in endoplas ...... palmitoyltransferase activity
@en
CPT1c is localized in endoplas ...... palmitoyltransferase activity
@nl
P2093
P2860
P3181
P356
P1476
CPT1c is localized in endoplas ...... palmitoyltransferase activity
@en
P2093
Adriana Y Sierra
Esther Gratacós
Fausto G Hegardt
Guillermina Asins
Jesús Ureña
Josep Clotet
Patricia Carrasco
P2860
P304
P3181
P356
10.1074/JBC.M707965200
P407
P577
2008-01-11T00:00:00Z