Intestinal tumor progression is associated with altered function of KLF5 - Wikidata - awgldk - TriplyDB

Intestinal tumor progression is associated with altered function of KLF5

Intestinal tumor progression is associated with altered function of KLF5

http://www.wikidata.org/entity/Q28579165

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Proteasomal degradation of the KLF5 transcription factor through a ubiquitin-independent pathway Krüppel-like factors 4 and 5: the yin and yang regulators of cellular proliferation Mammalian Krüppel-like factors in health and diseases The diverse functions of Krüppel-like factors 4 and 5 in epithelial biology and pathobiology Dietary exposure to soy or whey proteins alters colonic global gene expression profiles during rat colon tumorigenesis.Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.Potential prognostic, diagnostic and therapeutic markers for human gastric cancer The double life of KLF5: Opposing roles in regulation of gene-expression, cellular function, and transformation Human Kruppel-like factor 5 is a target of the E3 ubiquitin ligase WWP1 for proteolysis in epithelial cells Protein kinase C alpha signaling inhibits cyclin D1 translation in intestinal epithelial cells Synthetic retinoid Am80 inhibits interaction of KLF5 with RAR alpha through inducing KLF5 dephosphorylation mediated by the PI3K/Akt signaling in vascular smooth muscle cells Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium Protein inhibitor of activated STAT1 interacts with and up-regulates activities of the pro-proliferative transcription factor Krüppel-like factor 5.Dynamic transcription programs during ES cell differentiation towards mesoderm in serum versus serum-freeBMP4 culture.The induction of KLF5 transcription factor by progesterone contributes to progesterone-induced breast cancer cell proliferation and dedifferentiation.The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs.Differential regulation of cyclin D1 expression by protein kinase C α and ϵ signaling in intestinal epithelial cells.Kruppel-like factor 5 is not required for K-RasG12D lung tumorigenesis, but represses ABCG2 expression and is associated with better disease-specific survival.Krüppel-like factor 5 protects against murine colitis and activates JAK-STAT signaling in vivo.Interruption of KLF5 acetylation converts its function from tumor suppressor to tumor promoter in prostate cancer cells.Krüppel-like factor 5 protects against dextran sulfate sodium-induced colonic injury in mice by promoting epithelial repair Klf5 deletion promotes Pten deletion-initiated luminal-type mouse prostate tumors through multiple oncogenic signaling pathways Helicobacter pylori promotes the expression of Krüppel-like factor 5, a mediator of carcinogenesis, in vitro and in vivo.Krüppel-like factor 5 mediates cellular transformation during oncogenic KRAS-induced intestinal tumorigenesis Krüpple-like factor 5 is required for proper maintenance of adult intestinal crypt cellular proliferation.All-trans retinoic acid inhibits proliferation of intestinal epithelial cells by inhibiting expression of the gene encoding Kruppel-like factor 5 Krüppel-like factor 5 promotes mitosis by activating the cyclin B1/Cdc2 complex during oncogenic Ras-mediated transformation.Loss of transcription factor KLF5 in the context of p53 ablation drives invasive progression of human squamous cell cancer Esophageal squamous cell dysplasia and delayed differentiation with deletion of krüppel-like factor 4 in murine esophagus Mutational landscape of mucinous ovarian carcinoma and its neoplastic precursors.Stage matters: choosing relevant model systems to address hypotheses in diet and cancer chemoprevention research.The Pathobiology of Krüppel-like Factors in Colorectal Cancer.Restoring KLF5 in esophageal squamous cell cancer cells activates the JNK pathway leading to apoptosis and reduced cell survival.Molecular networks in microarray analysis.Oestrogen causes degradation of KLF5 by inducing the E3 ubiquitin ligase EFP in ER-positive breast cancer cells.Kruppel-like factor 5 transcription factor promotes microsomal prostaglandin E2 synthase 1 gene transcription in breast cancer Acetylation of KLF5 alters the assembly of p15 transcription factors in transforming growth factor-beta-mediated induction in epithelial cells.PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1 The role of Krüppel-like factors in the reprogramming of somatic cells to induced pluripotent stem cells.Estrogen-induced interaction between KLF5 and estrogen receptor (ER) suppresses the function of ER in ER-positive breast cancer cells

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P2860

Intestinal tumor progression is associated with altered function of KLF5

http://www.wikidata.org/entity/Q28579165

description

2004 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի մարտին հրատարակված գիտական հոդված

@hy

article publié dans la revue scientifique Journal of Biological Chemistry

@fr

artículu científicu espublizáu en 2004

@ast

im März 2004 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2004/03/26)

@sk

vědecký článek publikovaný v roce 2004

@cs

wetenschappelijk artikel (gepubliceerd op 2004/03/26)

@nl

наукова стаття, опублікована в березні 2004

@uk

name

Intestinal tumor progression is associated with altered function of KLF5

@ast

Intestinal tumor progression is associated with altered function of KLF5

@en

Intestinal tumor progression is associated with altered function of KLF5

@nl

type

label

Intestinal tumor progression is associated with altered function of KLF5

@ast

Intestinal tumor progression is associated with altered function of KLF5

@en

Intestinal tumor progression is associated with altered function of KLF5

@nl

prefLabel

Intestinal tumor progression is associated with altered function of KLF5

@ast

Intestinal tumor progression is associated with altered function of KLF5

@en

Intestinal tumor progression is associated with altered function of KLF5

@nl

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P1433

Journal of Biological Chemistry

P1476

Intestinal tumor progression is associated with altered function of KLF5

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P2093

Adrian R. Black

http://www.w3.org/2001/XMLSchema#string

Dongfeng Tan

http://www.w3.org/2001/XMLSchema#string

Jennifer D. Black

http://www.w3.org/2001/XMLSchema#string

Nicholas W. Bateman

http://www.w3.org/2001/XMLSchema#string

Richard G. Pestell

http://www.w3.org/2001/XMLSchema#string

P2860

Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest

Opposing effects of Krüppel-like factor 4 (gut-enriched Krüppel-like factor) and Krüppel-like factor 5 (intestinal-enriched Krüppel-like factor) on the promoter of the Krüppel-like factor 4 gene.

A gene encoding an intestinal-enriched member of the Krüppel-like factor family expressed in intestinal epithelial cells

Isolation and characterization of a gene encoding human Kruppel-like factor 5 (IKLF): binding to the CAAT/GT box of the mouse lactoferrin gene promoter

Intestinal-enriched Krüppel-like factor (Krüppel-like factor 5) is a positive regulator of cellular proliferation

Phosphorylation of Kruppel-like factor 5 (KLF5/IKLF) at the CBP interaction region enhances its transactivation function

Sp1- and Krüppel-like transcription factors

CDK inhibitors: positive and negative regulators of G1-phase progression

Regulated expression of the BTEB2 transcription factor in vascular smooth muscle cells: analysis of developmental and pathological expression profiles shows implications as a predictive factor for restenosis

KLF5 is frequently deleted and down-regulated but rarely mutated in prostate cancer

P304

12093–12101

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scholarly article

P356

10.1074/JBC.M311532200

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P407

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13

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P478

279

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2004-03-26T00:00:00Z

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P698

14726538

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