Molecular cloning and functional expression of the rat 175-kDa hyaluronan receptor for endocytosis
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Lipid Raft-Mediated Regulation of Hyaluronan-CD44 Interactions in Inflammation and CancerHyaluronan polymer length, grafting density, and surface poly(ethylene glycol) coating influence in vivo circulation and tumor targeting of hyaluronan-grafted liposomes.N-Glycans on the link domain of human HARE/Stabilin-2 are needed for hyaluronan binding to purified ecto-domain, but not for cellular endocytosis of hyaluronanExpression, processing, and glycosaminoglycan binding activity of the recombinant human 315-kDa hyaluronic acid receptor for endocytosis (HARE).Hyaluronan as an immune regulator in human diseases.Tissue-specific splice variants of HARE/Stabilin-2 are expressed in bone marrow, lymph node, and spleen.Activation of ERK and NF-κB during HARE-Mediated Heparin Uptake Require Only One of the Four Endocytic Motifs.Stabilin-1, a homeostatic scavenger receptor with multiple functions.Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver.The hyaluronan receptor for endocytosis (HARE) activates NF-κB-mediated gene expression in response to 40-400-kDa, but not smaller or larger, hyaluronans.Rat and human HARE/stabilin-2 are clearance receptors for high- and low-molecular-weight heparins.Hyaluronic acid receptor for endocytosis (HARE)-mediated endocytosis of hyaluronan, heparin, dermatan sulfate, and acetylated low density lipoprotein (AcLDL), but not chondroitin sulfate types A, C, D, or E, activates NF-κB-regulated gene expressionCharacterization of the recombinant rat 175-kDa hyaluronan receptor for endocytosis (HARE).Biology and biotechnology of hyaluronan.The hyaluronan receptor for endocytosis mediates hyaluronan-dependent signal transduction via extracellular signal-regulated kinases.Brain extracellular space, hyaluronan, and the prevention of epileptic seizures.Characterization of CD44-mediated cancer cell uptake and intracellular distribution of hyaluronan-grafted liposomes.The human hyaluronan receptor for endocytosis (HARE/Stabilin-2) is a systemic clearance receptor for heparinDistinctive properties of the hyaluronan-binding domain in the lymphatic endothelial receptor Lyve-1 and their implications for receptor function.A54 peptide-mediated functionalized gold nanocages for targeted delivery of DOX as a combinational photothermal-chemotherapy for liver cancer.The cytoplasmic domain of the hyaluronan receptor for endocytosis (HARE) contains multiple endocytic motifs targeting coated pit-mediated internalizationNormal lymphatic development and function in mice deficient for the lymphatic hyaluronan receptor LYVE-1Uptake of enzymatically-digested hyaluronan by liver endothelial cells in vivo and in vitro.Robust oil-core nanocapsules with hyaluronate-based shells as promising nanovehicles for lipophilic compounds.Receptor-Mediated Uptake of Phosphorothioate Antisense Oligonucleotides in Different Cell Types of the Liver.Genetic manipulation of sinusoidal endothelial cells.
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P2860
Molecular cloning and functional expression of the rat 175-kDa hyaluronan receptor for endocytosis
description
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
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im August 2002 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2002/08/01)
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vědecký článek publikovaný v roce 2002
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wetenschappelijk artikel (gepubliceerd op 2002/08/01)
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наукова стаття, опублікована в серпні 2002
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مقالة علمية (نشرت في أغسطس 2002)
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name
Molecular cloning and function ...... ronan receptor for endocytosis
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Molecular cloning and function ...... ronan receptor for endocytosis
@en
Molecular cloning and function ...... ronan receptor for endocytosis
@nl
type
label
Molecular cloning and function ...... ronan receptor for endocytosis
@ast
Molecular cloning and function ...... ronan receptor for endocytosis
@en
Molecular cloning and function ...... ronan receptor for endocytosis
@nl
prefLabel
Molecular cloning and function ...... ronan receptor for endocytosis
@ast
Molecular cloning and function ...... ronan receptor for endocytosis
@en
Molecular cloning and function ...... ronan receptor for endocytosis
@nl
P2093
P2860
P3181
P356
P1476
Molecular cloning and function ...... ronan receptor for endocytosis
@en
P2093
Amit Saxena
Janet A. Weigel
Paul H. Weigel
P2860
P304
P3181
P356
10.1091/MBC.02-03-0048
P577
2002-08-01T00:00:00Z