Suppression of the invasive capacity of rat ascites hepatoma cells by knockdown of Slingshot or LIM kinase
about
Slingshot isoform-specific regulation of cofilin-mediated vascular smooth muscle cell migration and neointima formationNon-overlapping activities of ADF and cofilin-1 during the migration of metastatic breast tumor cellsDamnacanthal, an effective inhibitor of LIM-kinase, inhibits cell migration and invasion.LIM kinase regulation of cytoskeletal dynamics is required for salivary gland branching morphogenesis.LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells.Genetic and epigenetic changes in chromosomally stable and unstable progeny of irradiated cellsMovers and shakers: cell cytoskeleton in cancer metastasis.Bis-aryl urea derivatives as potent and selective LIM kinase (Limk) inhibitors.LIM kinase 1 (LIMK1) interacts with tropomyosin-related kinase B (TrkB) and Mediates brain-derived neurotrophic factor (BDNF)-induced axonal elongation.Diallyl disulfide suppresses epithelial-mesenchymal transition, invasion and proliferation by downregulation of LIMK1 in gastric cancer.Silence of ezrin modifies migration and actin cytoskeleton rearrangements and enhances chemosensitivity of lung cancer cells in vitro.LIM domain kinases as potential therapeutic targets for neurofibromatosis type 2.The activated transforming growth factor-beta signaling pathway in peritoneal metastases is a potential therapeutic target in ovarian cancer.Ca2+/calmodulin-dependent protein kinase IV-mediated LIM kinase activation is critical for calcium signal-induced neurite outgrowth.Identification of para-Substituted Benzoic Acid Derivatives as Potent Inhibitors of the Protein Phosphatase Slingshot.A common cofilin activity cycle in invasive tumor cells and inflammatory cells.Molecular pathways: targeting the kinase effectors of RHO-family GTPases.Slingshot-1L, a cofilin phosphatase, induces primary breast cancer metastasis.SSH1 expression is associated with gastric cancer progression and predicts a poor prognosis.CaMKIIβ-mediated LIM-kinase activation plays a crucial role in BDNF-induced neuritogenesis.The impact of phosphatases on proliferative and survival signaling in cancer.LIM kinase inhibition reduces breast cancer growth and invasiveness but systemic inhibition does not reduce metastasis in mice.
P2860
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P2860
Suppression of the invasive capacity of rat ascites hepatoma cells by knockdown of Slingshot or LIM kinase
description
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2008
@ast
im März 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/03/07)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/03/07)
@nl
наукова стаття, опублікована в березні 2008
@uk
name
Suppression of the invasive ca ...... own of Slingshot or LIM kinase
@ast
Suppression of the invasive ca ...... own of Slingshot or LIM kinase
@en
Suppression of the invasive ca ...... own of Slingshot or LIM kinase
@nl
type
label
Suppression of the invasive ca ...... own of Slingshot or LIM kinase
@ast
Suppression of the invasive ca ...... own of Slingshot or LIM kinase
@en
Suppression of the invasive ca ...... own of Slingshot or LIM kinase
@nl
prefLabel
Suppression of the invasive ca ...... own of Slingshot or LIM kinase
@ast
Suppression of the invasive ca ...... own of Slingshot or LIM kinase
@en
Suppression of the invasive ca ...... own of Slingshot or LIM kinase
@nl
P2093
P2860
P356
P1476
Suppression of the invasive ca ...... own of Slingshot or LIM kinase
@en
P2093
Kazumasa Ohashi
Kensaku Mizuno
Masahiro Inoue
Mutsuko Mukai
Yuji Horita
P2860
P304
P356
10.1074/JBC.M706538200
P407
P577
2008-03-07T00:00:00Z